SkinMedica HA5 Hydra Collagen Replenish + Restore Hydrator

1.7 fl oz

4.6 View 297 reviews

| HSA/FSA Eligible LMN Required

$153.60

~~$192.00~~ 20% Off

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Highlights

Provides immediate and long-term hydration
Boosts hyaluronic acid production

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$192.00 $153.60

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Product Overview

SkinMedica HA5 Hydra Collagen Replenish + Restore Hydrator restores hyaluronic acid production deep in skin for a plump, dewy complexion.

Featuring five forms of hyaluronic acid, plus a Hydra Collagen Complex for immediate hydration, this lightweight cream to water serum restores endogenous hyaluronic acid production deep within the skin's layer to provide immediate results that last 48 hours. Potent and powerful, this serum improves hydration, reinforces the skin barrier and boosts skin's water-holding capacity.

Clinical Results:

Patients reported their skin looked approximately 3 years younger by week 12
93% reported it made their skin appear more healthy and dewy in 2 weeks
85% experienced visibly pumper skin in 12 weeks
97% agreed this product improved skin quality at 12 weeks
100% experienced confidence in their skin by week 12

Key Features:

HA5®, featuring five proprietary forms of hyaluronic acid, releases different molecular weights and types of hyaluronic acid (2x the previous HA5 formula) to instantly smooth the appearance of fine lines and wrinkles on the skin's surface
A Hydra Collagen Complex, derived from vegan collagen, provides optimal immediate hydration
Proprietary Advanced VITISENSCE® Technology provides long-term hydration and targets existing collagens within the skin to boost hydration naturally
Contains 100% vegan collagen complex; not a certified animal-derived collagen product

Highlights

Provides immediate and long-term hydration
Boosts hyaluronic acid production
Made with Vegan Collagen

Ingredients

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Questions & Answers (7)

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Product Specifications

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About the Brand

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Customer Reviews (297)

Overall Rating

4.6

Based on 297 reviews

Review Summary

5 Stars

246

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297 Reviews

Andijxn

from Texas

Age Group: 50-59

Wavy, Dry Hair

Combination Skin

Verified Purchase

June 18, 2026

Love this product!

Moisturising and has a pleasant scent when applied. I’m new to this product, but so far I’m impressed with it

0 people found this helpful

AuntieKO

from California

Age Group: 60-69

Dry Skin

Verified Purchase

June 07, 2026

Too early to tell

I just started using this product so I’m not sure how I feel about it yet. No immediate visible results. My skin doesn’t feel as soft and moisturized as with other products I have tried with similar ingredients so I’m not sure if I will buy again. It’s expensive and others seem to work as well for less money?

0 people found this helpful

LovelySkin Customer

from Washington

Age Group: 60-69

Mature Skin

Verified Purchase

June 01, 2026

Love this product

I’ve been using this for years now and it’s my go to for a hyaluronic acid product. Quite hydrating and leaves my skin very soft and smooth.

1 person found this helpful

LovelySkin Customer

from New Jersey

Age Group: 60-69

Combination Skin

Verified Purchase

June 01, 2026

Love SkinMedica products!

I love the Skin Medica products. HA5 gives a fresh, hydrated look, and I notice the change in my skin if I run out of product. I highly recommend.

1 person found this helpful

LovelySkin Customer

from Texas

Age Group: 70-79

Oily Skin

Verified Purchase

May 31, 2026

Many Years User of SkinMedica HA5

For many years I have happily used SkinMedica HA5. This new formula does work and adds somewhat of a glow. However the new formula stings my eyes if I perspire even a little. I can apply the new formula ONLY UNDER my eyes and carefully away from the edge. At night my oily skin allows the application to ooze into my eyes, so I now only use HA5 with Collagen only during the day. So sorry that the formula changed! I continue to use it but with very careful application under the eyes only.

1 person found this helpful

LindaW

from New York

Age Group: 50-59

Mature Skin

Verified Purchase

May 29, 2026

Less product more money

I am a huge fan of this product but now they are charging more money for less of it. Not liking that at all!!

1 person found this helpful

JennaBooth

from Tennessee

Age Group: 40-49

Straight Hair

Normal Skin

Verified Purchase

May 26, 2026

Love the new packaging

I’ve been using skin medica products for years. Love the way it hydrates my skin. Adore the new packaging.

0 people found this helpful

LovelySkin Customer

from Minnesota

Age Group: 70-79

Mature Skin

Verified Purchase

May 22, 2026

Makes skin so hydrated!

This made my skin so hydrated and youthful! Although it's expensive, I can't see being without it!

1 person found this helpful

BruceC

from California

Verified Purchase

May 18, 2026

A staple in my skincare routine

I’ve tried a lot of skincare products over the years, but SkinMedica HA5 Hydra Collagen Replenish + Restore Hydrator is truly one of the best I’ve ever used. My skin looks smoother, healthier, deeply hydrated, and noticeably more radiant. It gives my face that fresh, glowing look without feeling heavy or greasy. What I love most is how quickly it absorbs and how soft and plump my skin feels afterward. Fine lines appear softened, and my skin tone just looks more vibrant and alive. I’ve also noticed my skin stays hydrated throughout the entire day. This has absolutely become a staple in my skincare routine. Expensive, yes… but for me, completely worth it.

1 person found this helpful

Mops

from California

Age Group: 80+

Straight, Color treated hair

Combination Skin

Verified Purchase

May 16, 2026

SkinMedica HA5 Hydra

I’ve been using SkinMedica HA5 for some time now. It has helped my skin stay moisturized more than other brands I have tried. The price is a bit higher than other HA5 but worth the extra $$ as it has a more moisturizing effect on my skin.

2 people found this helpful

Plg

from North Carolina

Age Group: 70-79

Combination Skin

Verified Purchase

May 12, 2026

Very smoothing

This is a wonderful hydrator. Makes my skin super smooth and soft…. I use it after the TNS Advanced routinely and like very much. I do recommend.!

2 people found this helpful

Abeachgirl

Age Group: 40-49

Curly Hair

Combination Skin

Verified Purchase

May 05, 2026

The BEST hydrator

The absolute best face and neck hydrator. Skin feels smooth and soft. Looks plump and healthy. I receive so many compliments after applying. It is the best!

2 people found this helpful

LovelySkin Customer

from Missouri

Age Group: 50-59

Verified Purchase

May 04, 2026

Great Product

Keeps my skin feeling fresh & hydrated. I highly recommend this brand & product!

1 person found this helpful

LovelySkin Customer

Age Group: 70-79

Verified Purchase

May 01, 2026

Love it

Leaves my face smooth without a heavy residue. Pricey but worth it.

1 person found this helpful

LovelySkin Customer

from Minnesota

Age Group: 40-49

Verified Purchase

April 27, 2026

Amazing

I wasn’t sure about this hydrator but thought I would give it a shot and wow! It really delivers all it says it does. I won’t be without it as I’ve already placed it on my auto ship line up.

3 people found this helpful

LovelySkin Customer

from Iowa

Age Group: 40-49

Verified Purchase

April 24, 2026

Bring back the old!

This new formula is not it. I had the previous version on subscription for years. Worked beautifully!! This is thin and my face does not feel hydrated. Makes it difficult to apply my foundation. The worst part is the smell, it smells like it went bad! I’m about to throw it out and move on to another brand. Please bring back the old version Skinmedica!

5 people found this helpful

LovelySkin Customer

Verified Purchase

April 23, 2026

Super hydrating!

This product hydrates my normally dry skin It absorbs quickly over the SkinMedica TNS Serum Highly Recommend

2 people found this helpful

KKaren

from Nebraska

Age Group: 70-79

Mature Skin

Verified Purchase

April 22, 2026

SkinMedica HA5

This is one of my favorite products that I continue to get for over 5 years. I have it on repeat order so I don’t run out. It has kept my skin hydrated and love the way it goes on. Also it does not have a strong smell. Love it!

2 people found this helpful

GMG

from Illinois

Verified Purchase

April 21, 2026

SkinMedica HA5 Hydra Collagen + Restore Hydrator

Wonder product!! Keeps my skin feeling fresh & hydrated. I highly recommend this brand & product. I keep several in reserve so I don’t run out.

2 people found this helpful

FlygirlD

from Arkansas

Normal Skin

Verified Purchase

April 10, 2026

Nice moisturizer

Love the moisturizer effect of this product. I put it on top of day and nighttime serums or treatments. Have been using product for 3 week. Seem to “ soften” fine lines. The moisture seems to last all day on me, but not heavy or oily. Might consider keeping this one in my skincare routine. No break outs or irritation.

4 people found this helpful

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SkinMedica HA5 Hydra Collagen Replenish + Restore Hydrator

Product Overview

SkinMedica HA5 Hydra Collagen Replenish + Restore Hydrator restores hyaluronic acid production deep in skin for a plump, dewy complexion.

Highlights

Ingredients

Directions

Shipping & Returns

Questions & Answers (7)

Product Specifications

Special Offers

About the Brand

Featured In

Customer Reviews (297)

Overall Rating

Review Summary

Write a Review

Love this product!

Too early to tell

Love this product

Love SkinMedica products!

Many Years User of SkinMedica HA5

Less product more money

Love the new packaging

Makes skin so hydrated!

A staple in my skincare routine

SkinMedica HA5 Hydra

Very smoothing

The BEST hydrator

Great Product

Love it

Amazing

Bring back the old!

Super hydrating!

SkinMedica HA5

SkinMedica HA5 Hydra Collagen + Restore Hydrator

Nice moisturizer

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