SkinMedica HA5 Hydra Collagen Replenish + Restore Hydrator

Product Overview

SkinMedica HA5 Hydra Collagen Replenish + Restore Hydrator restores hyaluronic acid production deep in skin for a plump, dewy complexion.

Featuring five forms of hyaluronic acid, plus a Hydra Collagen Complex for immediate hydration, this lightweight cream to water serum restores endogenous hyaluronic acid production deep within the skin's layer to provide immediate results that last 48 hours. Potent and powerful, this serum improves hydration, reinforces the skin barrier and boosts skin's water-holding capacity.

Clinical Results:

Patients reported their skin looked approximately 3 years younger by week 12
93% reported it made their skin appear more healthy and dewy in 2 weeks
85% experienced visibly pumper skin in 12 weeks
97% agreed this product improved skin quality at 12 weeks
100% experienced confidence in their skin by week 12

Key Features:

HA5®, featuring five proprietary forms of hyaluronic acid, releases different molecular weights and types of hyaluronic acid (2x the previous HA5 formula) to instantly smooth the appearance of fine lines and wrinkles on the skin's surface
A Hydra Collagen Complex, derived from vegan collagen, provides optimal immediate hydration
Proprietary Advanced VITISENSCE® Technology provides long-term hydration and targets existing collagens within the skin to boost hydration naturally

Highlights

Deeply moisturizing
Provides immediate and long-term hydration
Boosts hyaluronic acid production

Ingredients

Directions

Shipping & Returns

Free U.S. Shipping. Period. View Our Shipping Policy

Return Policy: View Our Return Policy

Availability: In stock & ready to ship! .

Questions & Answers (7)

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Product Specifications

About the Brand

Featured In

Customer Reviews (218)

Overall Rating

4.6

Based on 218 reviews

Review Summary

5 Stars

181

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218 Reviews

LovelySkin Customer

from Pennsylvania

Age Group: 40-49

Dry Skin

Verified Purchase

December 04, 2025

Amazing moisturizer

Love this product! I have dry skin, especially in the winter months, and this moisturizer has been a game changer for me. My skin feels great all day.

0 people found this helpful

Nurse1974

from Kentucky

Age Group: 50-59

Curly Hair

Combination Skin

Verified Purchase

December 04, 2025

Returned! Please bring back the original!

Nothing like the original HA5! I returned this! I’ve used the original for many years and loved it so much! I never went without it! I received this in its place, and was very disappointed. The original felt so smooth and just melted into my skin. This one, however felt greasy, made me break out, and smells horrible. I’ve been looking for a dupe for the original since they sadly made the decision to discontinue it and replace it with this one. I keep hoping that they will end up bringing the old back! Please bring back the original HA5!!!

0 people found this helpful

Mac

Age Group: 50-59

Combination Skin

Verified Purchase

November 30, 2025

HA + collagen

Absolutely love this product, from the instant I put it on I felt my skin absorb and feel hydrated. A great add on for dewy, supple skin

0 people found this helpful

LovelySkin Customer

Verified Purchase

November 30, 2025

Amazing + Extremely Moisturizing for My Skin

I have been loving how moisturized my skin is now after switching to this product. My esthetician noticed a difference in my skin as well, stating that my skin feels more moisturized and it was definitely this product that made the difference.

0 people found this helpful

Robin58

from Oregon

Age Group: 60-69

Verified Purchase

November 29, 2025

So far I think it’s great

Haven’t been using it long but I like what I feel and see so far.

0 people found this helpful

CherG

from Massachusetts

Verified Purchase

November 27, 2025

Excellent Hydration

I use this product at night before I apply overnight cream. My skin just soaks this in. My skin is so very soft and hydrated after using this product.

0 people found this helpful

Wrenn

from Pennsylvania

Age Group: 50-59

Wavy, Color treated hair

Dry Skin

Verified Purchase

November 26, 2025

SkinMedica HA5 Hydra Collagen Replenish + Restore Hydrator

I use HA5 Hydra Collagen Replenish + Restore after the TNS serum. It goes on smoothly and feels luxurious. My moisturizer goes on afterwards without pilling. My skin looks better than ever since moving towards more SkinMedica products.

0 people found this helpful

SunnySkin123

from South Carolina

Age Group: 40-49

Straight Hair

Normal Skin

Verified Purchase

November 25, 2025

Love this

I love this HA. I know it’s expensive but it is wonderful on my skin. I love how it blends right into my skin. I have given as gifts and everyone always loves.

0 people found this helpful

Carrie4243

from Arizona

Age Group: 50-59

Dry Skin

Verified Purchase

November 22, 2025

A staple in my routine

I loved this product. It keeps me hydrated.and moisturized.I’ve been using it for a few months. You can’t go wrong with this product in your skincare routine

0 people found this helpful

Moel

from Minnesota

Age Group: 40-49

Mature Skin

Verified Purchase

November 21, 2025

Feels great!

I needed something extra on top of my retinol to help keep my face from getting to dry and this has done the trick. Feels so nice on your skin!

0 people found this helpful

LovelySkin Customer

from Missouri

Age Group: 60-69

Wavy, Color treated hair

Mature Skin

Verified Purchase

November 21, 2025

HA5 Hydra Collagen Replenish

I needed to re order the Skin Medica HA 5. And I noticed the one I had been using was discontinued. So I ordered this one. It is also called a hydra collagen replenish and restore hydrator. I think it is thicker and creamier. I love it. I loved the previous product but have really noticed more hydration with this combination. I would advise to let it dry before applying makeup. LovelySkin delivery was quick as usual.

0 people found this helpful

Chappytini

from Connecticut

Age Group: 60-69

Verified Purchase

November 13, 2025

Great for your daily skincare routine

I love SkinMedica products. I use this along with the Vitamin C&E complex. It goes on a little thick, but you get a lot with one pump of the applicator. My face feels smooth and plump. Try it!

0 people found this helpful

SMC

from Colorado

Age Group: 70-79

Mature Skin

Verified Purchase

November 12, 2025

MUCH better than the original HA5!

I tried the old version of HA5 but it just didn't feel like I was getting the moisture retention I was looking for. So I stopped using it. Time passed and then I got an HA5 Hydra Collagen Replenish and Restore sample. I use this version now regularly after some of my serums that are more "watery" and drying. It does not leave my skin greasy. It's just very soft and plumper. I follow it with an SPF in the morning or use it as my final topper at night if I have used a less moisturizing night treatment. Highly recommend.

1 person found this helpful

KSM

from New Jersey

Age Group: 60-69

Straight, Dry Hair

Normal Skin

Verified Purchase

October 25, 2025

Really works!

I really like this product a lot. It's lightweight but really hydrates the skin and diminishes the look of fine lines. Over time, I believe my skin looks plumper and more youthful since I have been using it. It's expensive but worth it. Highly recommend!

2 people found this helpful

LovelySkin Customer

from Georgia

Age Group: 70-79

Wavy, Dry Hair

Mature Skin

Verified Purchase

October 23, 2025

Love this product

I know I am doing the best for my skin with this product. Suffering from very dry skin makes this hydrator a must for me. I don’t have to know all the science to see the difference it makes for me. I highly recommend it and use it interchangeably with TNS advanced serum, also by SkinMedica.

3 people found this helpful

LovelySkin Customer

from California

Verified Purchase

October 20, 2025

Hydrating

Skin looks more hydrated and less fine lines with this product

1 person found this helpful

LovelySkin Customer

from Massachusetts

Age Group: 60-69

Dry Skin

Verified Purchase

October 17, 2025

HA5 hydratir

Love this product! Feels glorious on and won’t be without it

1 person found this helpful

LovelySkin Customer

from Georgia

Verified Purchase

October 11, 2025

Felt nice, not worth the money

I really wanted to love this, but for the price, it's not at all worth it. It feels very nice, but there was not any noticable difference between this and other similar products I used at half the price.

1 person found this helpful

SSW

from Kansas

Age Group: 60-69

Dry Skin

Verified Purchase

October 09, 2025

SkinMedica HA5

I have been using this product for several years now! The reason why I’ve continued to use it? It is the absolute best!

1 person found this helpful

LovelySkin Customer

from Virginia

Age Group: 70-79

Verified Purchase

October 09, 2025

Great Product

I have used this Hydrator for many years and continue to buy it because it works. I recommend it.

0 people found this helpful

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SkinMedica HA5 Hydra Collagen Replenish + Restore Hydrator

Product Overview

SkinMedica HA5 Hydra Collagen Replenish + Restore Hydrator restores hyaluronic acid production deep in skin for a plump, dewy complexion.

Highlights

Ingredients

Directions

Shipping & Returns

Questions & Answers (7)

Product Specifications

About the Brand

Featured In

Customer Reviews (218)

Overall Rating

Review Summary

Write a Review

Amazing moisturizer

Returned! Please bring back the original!

HA + collagen

Amazing + Extremely Moisturizing for My Skin

So far I think it’s great

Excellent Hydration

SkinMedica HA5 Hydra Collagen Replenish + Restore Hydrator

Love this

A staple in my routine

Feels great!

HA5 Hydra Collagen Replenish

Great for your daily skincare routine

MUCH better than the original HA5!

Really works!

Love this product

Hydrating

HA5 hydratir

Felt nice, not worth the money

SkinMedica HA5

Great Product

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