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SkinMedica HA5 Hydra Collagen Replenish + Restore Hydrator
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SkinMedica HA5 Hydra Collagen Replenish + Restore Hydrator

2.0 fl oz
4.6 View 243 reviews
| HSA|FSA Eligible LMN Required
$192.00

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Highlights
  • Deeply moisturizing
  • Provides immediate and long-term hydration
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Product Overview

SkinMedica HA5 Hydra Collagen Replenish + Restore Hydrator restores hyaluronic acid production deep in skin for a plump, dewy complexion.

Featuring five forms of hyaluronic acid, plus a Hydra Collagen Complex for immediate hydration, this lightweight cream to water serum restores endogenous hyaluronic acid production deep within the skin's layer to provide immediate results that last 48 hours. Potent and powerful, this serum improves hydration, reinforces the skin barrier and boosts skin's water-holding capacity.

Clinical Results:

  • Patients reported their skin looked approximately 3 years younger by week 12
  • 93% reported it made their skin appear more healthy and dewy in 2 weeks
  • 85% experienced visibly pumper skin in 12 weeks
  • 97% agreed this product improved skin quality at 12 weeks
  • 100% experienced confidence in their skin by week 12

Key Features:

  • HA5®, featuring five proprietary forms of hyaluronic acid, releases different molecular weights and types of hyaluronic acid (2x the previous HA5 formula) to instantly smooth the appearance of fine lines and wrinkles on the skin's surface
  • A Hydra Collagen Complex, derived from vegan collagen, provides optimal immediate hydration
  • Proprietary Advanced VITISENSCE® Technology provides long-term hydration and targets existing collagens within the skin to boost hydration naturally

Highlights

  • Deeply moisturizing
  • Provides immediate and long-term hydration
  • Boosts hyaluronic acid production

Ingredients

Directions

Shipping & Returns

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Return Policy: This product is non-returnable

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Special Shipping Requirements: ORM-D Class
ORM-D classified products such as aerosol sprays, nail polish, perfume and products with high alcohol content may only be shipped using a ground method within the Continental US.

Availability: In stock & ready to ship! .

Questions & Answers (7)

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Product Specifications

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About the Brand

Customer Reviews (243)

Overall Rating

4.6
Based on 243 reviews

Review Summary

5 Stars
204 reviews
4 Stars
22 reviews
3 Stars
4 reviews
2 Stars
4 reviews
1 Star
9 reviews

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243 Reviews

Profile picture of CandiceMichelle.

CandiceMichelle

from Texas

Age Group: 30-39

Straight Hair

Verified Purchase

February 04, 2026

Forever staple

It jus makes your skin look and feel amazing like silk!

0 people found this helpful

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LovelySkin Customer

from Nebraska

Verified Purchase

February 03, 2026

Perfect for my face and neck

I use this every morning and night.Even on days I’m in a hurry I use this without makeup and my skin looks fresh. Moisturizes without being greasy or heavy. Love it!

0 people found this helpful

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LovelySkin Customer

from Indiana

Age Group: 40-49

Curly, Color treated hair

Combination Skin

Verified Purchase

February 03, 2026

Love this!

This has changed my skin so much. It was dry and flaky with an oily t zone. After just one use I noticed a difference. My skin healed and hasn’t broke out.

0 people found this helpful

Profile picture of Bow.

Bow

from Kansas

Age Group: 60-69

Straight Hair

Mature Skin

Verified Purchase

January 30, 2026

SkinMedica HA5 Hydra Collagen Replenish + Restore Hydrator

Have been using this for several months now, from what I understand this has replaced the HA5. The product is silky on your skin, it seems to make the skin smoother with the Collagen, am happy with it. As far as what the long term results will be, will have to wait.

0 people found this helpful

Profile picture of Ammie09.

Ammie09

from Texas

Verified Purchase

January 28, 2026

A Pleasant Surprise

I have to admit I was originally not pleased that the original HA5 had been replaced because I loved the original. Now I have to say I am THRILLED with this new version. It is wonderfully moisturizing and I can cover all of my face and neck with two small pumps instead of the three I had to use with the former version. If I had to choose only one skin care product to own, it would absolutely be this one.

0 people found this helpful

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LovelySkin Customer

from Georgia

Verified Purchase

January 27, 2026

Soothing and Effective

I have used HA5 for several years now and rely on it morning and night. My skin is sensitive and this product has never caused an adverse reaction of any kind. A definite essential in my arsenal against aging, it combines well with other products.

0 people found this helpful

Profile picture of Bobby.

Bobby

Verified Purchase

January 21, 2026

Face moisturizer

This is a great face moisturizer that I have used for years. Plastic surgeon recommended this

0 people found this helpful

Profile picture of ROMANHOLIDAY.

ROMANHOLIDAY

Age Group: 70-79

Mature Skin

Verified Purchase

January 20, 2026

Wonderful Hydration

The new formula and packaging are winners all around. Don't believe the social media comments about Korean products and their ability to provide hydration. This is the real deal. Yes, it is a bit pricey but it works -- like all SkinMedica products. And you no longer have to wet your skin prior to applying.

1 person found this helpful

Profile picture of Kmz7.

Kmz7

from Illinois

Verified Purchase

January 16, 2026

Old formula was better

This new formula is average at best - does nothing that I can tell. The old formula gave VISIBLE results immediately. Not sure why they changed it. I’m sending this one back.

4 people found this helpful

Profile picture of Kappy.

Kappy

from California

Verified Purchase

January 13, 2026

Fabulous moisture retention.

I use HA5 every morning and my skin retains moisture all throughout the day. I would recommend it highly.

0 people found this helpful

Profile picture of Rommie.

Rommie

Age Group: 60-69

Curly, Dry Hair

Mature Skin

Verified Purchase

January 12, 2026

SkinMedica HA5 Hydra Collagen Replenish Restore

I love this product. It makes my skin feel very hydrated and silky.

0 people found this helpful

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LovelySkin Customer

from Nevada

Age Group: 50-59

Wavy Hair

Normal Skin

Verified Purchase

January 12, 2026

Great serum moisturizer

I love this product. I’ve been using it since it came out. I put it on before my moisturizer and other serums, including retinol. Helps keep my skin moisturized.

0 people found this helpful

Profile picture of Janhockeyface.

Janhockeyface

from Vermont

Age Group: 60-69

Straight Hair

Mature Skin

Verified Purchase

January 12, 2026

HA5 Hydra collagen replenish

I am 66 years old and use this religiously , daily, along with my other skinmedica products. It goes on easy and gives my face a nice glow under makeup.

1 person found this helpful

Profile picture of tleeworley.

tleeworley

Age Group: 60-69

Straight, Color treated hair

Mature Skin

Verified Purchase

January 10, 2026

Love HA5 Hydra Collagen Replenish and Restore Hydrator

I first used this product when I received it as a gift. Most of the products I use are introduced to me through the gift program you have. The product is awesome. I love the way it makes your face feel. I just bought the full size product to see the results I received after using it for 4-6 weeks. Five stars on this product and brand. Thanks for introducing it to me.

0 people found this helpful

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LovelySkin Customer

from Texas

Age Group: 70-79

Straight, Color treated hair

Normal Skin

Verified Purchase

January 07, 2026

Supple Skin

I absolutely love SkinMedica HA5 Hydra Collagen Replenish + Restore Hydrator. I put it on following Skinceuticals CE Feurlic and follow it with sunscreen. My skin looks radiant and feels so supple. I think it has helped with fine lines and skin texture. I’m 71 so I appreciate anything that gives me a more youthful appearance and thus does.

1 person found this helpful

Profile picture of bpldstayyoung.

bpldstayyoung

from Mississippi

Verified Purchase

January 03, 2026

Great Product

At 78, I give this product credit for the compliments I continue to get on my skin and it’s anti-aging effects.

0 people found this helpful

Profile picture of Domi.

Domi

Age Group: 50-59

Mature Skin

Verified Purchase

January 03, 2026

Amazing!

This is my first time trying this product and I love it. Absorbs nicely and my face feels well hydrated.

1 person found this helpful

Profile picture of TXCPA.

TXCPA

from Texas

Age Group: 70-79

Straight, Dry Hair

Combination Skin

Verified Purchase

December 31, 2025

The Best!

I have been using Skin Medica for years. Next to TMS, this is the best product. I refuse to do without it! Even have my husband using it.

0 people found this helpful

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LovelySkin Customer

from California

Verified Purchase

December 31, 2025

Absolutely love this product!

I have used this product for years. It is lightweight but deeply hydrating. My skin feels smoother, more balanced, and never oily.

0 people found this helpful

Profile picture of TexasBarb.

TexasBarb

Verified Purchase

December 24, 2025

Very hydrating

Skinmedica HA5 is a very hydrating serum. I've been using it every night for several years, and my skin always looks very healthy in the morning. I would recommend this product to anyone especially seniors who want to keep their skin looking useful.

0 people found this helpful

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