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Peels and Exfoliators
La Roche-Posay Substiane [+] Serum
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La Roche-Posay Substiane Serum 30 ml / 1.0 fl oz

(formerly known as La Roche-Posay Substiane [+] Serum)

We're sorry, this product has been discontinued.

We recommend the following product instead:


  • Best suited for mature skin
  • Restores lost volume
  • Provides a boost of moisture

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Product Overview

Restore a youthful complexion with this skin firming serum.

Visible results on skin firmness in 4 hours. Visibly restores density and bounce. A concentrate with advanced technology: 6 clinical studies. 17 patents.

.With 2% LR 2412 to visibly restores volume on skin's surface

.A rich, fast absorbing and moisturizing texture with instant smoothing effect

.Use as a daily treatment for the loss of firmness and sagging skin Substiane [+] Serum is a highly concentrated daily treatment for mature skin formulated with:

.LR 2412 2%.Visibly restores volume on skin's surface

.PRO-XYLANE™ 3%: replenishes volume and helps protect skin's support structure

.LINACTYL 4%: helps replenish to visibly restore density and bounce

Shipping & Returns

Free U.S. Shipping. Period. View Our Shipping Policy

Return Policy: This product is non-returnable

Return Policy: View Our Return Policy

Special Shipping Requirements: ORM-D Class
ORM-D classified products such as aerosol sprays, nail polish, perfume and products with high alcohol content may only be shipped by UPS Ground within the Continental US.

Availability: This product has been discontinued

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Sat 9 - 3 p.m. CT
Sun / Holidays Closed
Labor Day (9/4) Closed