SkinMedica TNS® Advanced+ Serum Duo

Product Overview

SkinMedica TNS® Advanced+ Serum Duo helps soften wrinkles to support smoother, plumper skin in just two weeks.

Formulated with TNS®-MR, the next-generation growth factor blend, this serum duo helps to reveal more youthful-looking skin by visibly lifting sagging skin, improving tone and texture and helping skin to naturally repair itself. Renessensce (RSC) Advanced, a highly active blend of botanicals, peptides and marine extracts, supports skin renewal, while an innovative 2 Tripeptide Complex visibly firms.

Set Includes:

SkinMedica TNS® Advanced+ Serum (2 x 1.0 fl oz)

Key Features:

Spanish marine extract and green microalgae builds collagen and supports skin's repair process
Clinic studies show users felt they looked up to six years younger after twelve weeks
Antioxidants provide environmental defense to help prevent future signs of aging
Probiotics support a healthy skin microbiome
Fragrance-free formula

Highlights

Repairs cells with growth factors
Rebuilds collagen
Has a fragrance-free formula

Ingredients

Directions

Shipping & Returns

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Return Policy: View Our Return Policy

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Product Specifications

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About the Brand

Customer Reviews (1916)

Overall Rating

4.6

Based on 1916 reviews

Review Summary

5 Stars

1526

4 Stars

235

3 Stars

2 Stars

1 Star

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1916 Reviews

from South Carolina

Age Group: 40-49

Wavy, Color treated hair

Mature Skin

Verified Purchase

February 04, 2026

Funky Smell & Bad Pump

I wanted to love this, but the funky smell & malfunctioning pump were enough to override the positives. You can take the top apart and get more even distribution, but you shouldn’t have to. It definitely wastes some product until you get the pump working right. The smell is just plain bad, like something may have gone wrong. I also found that a different product gives my skin a better texture & glow, as a 49 year old dealing with some aging issues to address. It has growth factors as well, without the pump & smell issues.

0 people found this helpful

LovelySkin Customer

from Virginia

Verified Purchase

January 30, 2026

Amazing

The product is amazing I seen results in just a few weeks!

0 people found this helpful

JenniferJW

from Louisiana

Age Group: 50-59

Straight Hair

Mature Skin

Verified Purchase

January 28, 2026

SkinMedica TNS Advanced Serum

I love this product! I use it day and night and take it with me on all of my travels. I use it on the back of my hands too. Truly changes the appearance of your skin. Smoother, visible signs in texture and firmness.

1 person found this helpful

Finn

from California

Verified Purchase

January 25, 2026

a must have serum

I highly recommend this product. my skin never have looked so gorgeous and plump. This is a product i can’t live without!

1 person found this helpful

Awilson4

from Oklahoma

Age Group: 40-49

Straight, Color treated hair

Normal Skin

Verified Purchase

January 24, 2026

Still unsure

I really wanted to add an EGF into my routine and gave this a try. I really like the consistency and the way it lays on my skin but I haven't really noticed any changes or positive improvements to my skin. I think you have to give it every 60 days but based off of the cost I don't think I'm going to purchase this again. I do use other skin medical products I just don't think this one's for me.

2 people found this helpful

HeidiL

Age Group: 30-39

Wavy Hair

Dry Skin

Verified Purchase

January 21, 2026

One of My Favorites

I use this nightly as part of my routine to age gracefully, and it has become a must have for me. My skin feels smoother, firmer, and more refreshed, and I love knowing I am investing in long term skin health.

1 person found this helpful

ROMANHOLIDAY

Age Group: 70-79

Mature Skin

Verified Purchase

January 20, 2026

TNS Advanced Miracle Prodent

I haven't written a review about the new packaging of this supurb product. The new pump system is a vast imporvement over the old bottle. It is much easier to select each pump for distribution and they don't clog the way the old ones used to, The product is always spectacular - I have been using is for years. and although I recently turned 75, people always comment that I look in my 50s!! Try the new packaging and see for yourself!

5 people found this helpful

LovelySkin Customer

from Florida

Age Group: 70-79

Wavy hair, Dry/flaky scalp

Mature Skin

Verified Purchase

January 17, 2026

TNS Advanced Serum

The new packaging is fabulous!!!! It makes way more sense than the other packaging. It solves the problems that were present with the old packaging like uneven amounts being dispersed. the product is great and always has been. I'm 74 and it gives me the confidence that I am doing everything I can for the best-looking skin. I used to use .25 retinol every day. My skin since I've gotten older is so sensitive the retinol is a bit too strong for me. It used to itch on my neck area so bad I had to stop. It was a lot cheaper. I wish I could still do it. Niacidimide seems to also be a good new alternative in a not too strong version. Anyway, I adore my TNS Advanced Serum. I hope the price doesn't go up any time soon. I am stretching to afford it now. Love you guys!!!!!

3 people found this helpful

LovelySkin Customer

from Texas

Age Group: 70-79

Normal Skin

Verified Purchase

January 16, 2026

Skin Medica TNS

Great product. Visibly reduces sagging skin.

2 people found this helpful

Cindylee

from New York

Age Group: 60-69

Straight, Color treated hair

Normal Skin

Verified Purchase

January 14, 2026

Sensational

I’ve been using this for several years and people think I’m 20-15 years younger than I am .

2 people found this helpful

Matty617

from Massachusetts

Age Group: 60-69

Verified Purchase

January 13, 2026

Love

I don’t know is it makes a difference yet but i like using it. So far so good

0 people found this helpful

Bumperw

from Florida

Verified Purchase

January 06, 2026

Expectations not met

I read many reviews for this product, some by consumers and others by dermatologists, that were highly favorable. I expected this product to improve fine lines and firmness as well as to promote overall skin health. I just finished my third container and I see NO difference at all in my skin. I am canceling my autoship and will find a product that delivers. I mean really, a drug store product is probably as effective as this one. It was a dud for me.

3 people found this helpful

LovelySkin Customer

from Florida

Age Group: 50-59

Verified Purchase

January 06, 2026

Excellent

I have been using this off and on for several years and always go back. This gives my skin a softness and a radiance that no other product has provided. It has a very slight scent that I really like. I also think it has improved my under eye area. Overall, great results.

1 person found this helpful

Zydeco71

from Alabama

Age Group: 50-59

Straight, Dry Hair

Normal Skin

Verified Purchase

January 03, 2026

Holy grail… not sure

I have been using this for several years and like it because it has several products combined in one but I honestly do not think it is any better than drugstore products.

4 people found this helpful

LovelySkin Customer

from Nevada

Verified Purchase

January 02, 2026

What can I say

Did I want this to not work? Yes of course, for the price I was hoping it would be horrible and I could sigh in relief as I return it. However that was not the case, and I’m currently on my third restock. What can I say.. it’s worth it!

2 people found this helpful

LovelySkin Customer

from South Carolina

Verified Purchase

January 02, 2026

So far, so good

I’ve not used this long enough to see true benefit but I have used it long enough to see that it doesn’t clog my pores or irritate my combination, sensitive skin. Currently using on my face and neck.

1 person found this helpful

LouiseIP

Verified Purchase

December 31, 2025

Love it!

I look at myself in a mirror and see a woman 15 years younger only a few days after I started to use this cream

1 person found this helpful

Melissamann

from Nebraska

Verified Purchase

December 30, 2025

Love love love

I am in love with this product. Feels great on my skin. Been using about a month and am already seeing a huge difference!!!!

1 person found this helpful

LovelySkin Customer

from California

Verified Purchase

December 30, 2025

This improved my skin OVERNIGHT!

I have good skin for my age (60+), but it's sensitive, dry & very reactive. I have a simple skincare regimen & only use quality products I buy from Lovelyskin. Based on TNS's amazing customer reviews, I bought a bottle and, I swear, I woke up with better looking skin. I've used it for months now & I love it. This product really works!

2 people found this helpful

LovelySkin Customer

from Florida

Age Group: 50-59

Straight Hair

Verified Purchase

December 29, 2025

Fine lines

This product works very well on fine lines. You have to definitely apply as directed and keep using otherwise lines come back.

2 people found this helpful

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SkinMedica TNS® Advanced+ Serum Duo

Product Overview

SkinMedica TNS® Advanced+ Serum Duo helps soften wrinkles to support smoother, plumper skin in just two weeks.

Highlights

Ingredients

Directions

Shipping & Returns

Questions & Answers

Product Specifications

Special Offers

About the Brand

Customer Reviews (1916)

Overall Rating

Review Summary

Write a Review

Funky Smell & Bad Pump

Amazing

SkinMedica TNS Advanced Serum

a must have serum

Still unsure

One of My Favorites

TNS Advanced Miracle Prodent

TNS Advanced Serum

Skin Medica TNS

Sensational

Love

Expectations not met

Excellent

Holy grail… not sure

What can I say

So far, so good

Love it!

Love love love

This improved my skin OVERNIGHT!

Fine lines

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