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Inspired by the effects of neurotoxin injections, this serum is formulated with an Advanced Peptide Complex and a Glass Skin Complex to smooth nine types of contraction and expression lines to rejuvenate skin for a renewed glow. Neurotoxin injections are a popular in-office treatment used to treat expression wrinkles caused by muscle contractions.
When paired together, P-TIOX and neurotoxin injections work synergistically to help reduce the appearance of wrinkles, delivering fast, long-lasting results. Versatile and innovative, this serum is also effective on its own to smooth skin, refine pores and reveal glass skin radiance in one week of use.
Clinical Results:
Key Features:
SkinCeuticals is removing the plastic shrink seal around the neck of SkinCeuticals P-TIOX Wrinkle Modulating Peptide Serum as part of its commitment to sustainability. The tamper-proof outer carton seal remains unchanged, and rigorous testing confirms full bottle and formula integrity.
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313 Reviews
AbbyB19
from Michigan
Verified Purchase
I use the ptiox serum and cream by skinceuticals twice per day. I find an immediate improvement in the appearance of my skin and I feel its condition has improved since using them
1 person found this helpful
LovelySkin Customer
Age Group: 50-59
Verified Purchase
My absolute favorite product right now - it has really improved the bounce and glow to my skin. I was so impressed that I bought the moisturizer.
1 person found this helpful
TexasBarb
from Texas
Age Group: 60-69
Wavy hair, Damage & split ends
Mature Skin
Verified Purchase
I've been using this product for several years, and it's really help maintain my Botox. I put it on my forehead and around my mouth, and I see really great results. I recommend this product.
1 person found this helpful
GabrielaP
from California
Verified Purchase
This serum is phenomenal! I use it in the morning and I use the cream version at night. I immediately leaves my skin feeling moisturised and glowing. I will continue to use.
0 people found this helpful
Painswick
from Arizona
Age Group: 80+
Wavy Hair
Mature Skin
Verified Purchase
The texture of my skin since using is very smooth. I have never had injections but I am doing red light therapy & using serum morning and evening. I am 85 & only have expression lines. I am very pleased with this regimen; I get lots of compliments on my skin.
2 people found this helpful
LovelySkin Customer
from Pennsylvania
Age Group: 20-29
Normal Skin
Verified Purchase
This is an amazing peptide serum, the texture is lovely & it definitely has improved the quality of my skin. I’ve noticed improvement in a fine line & brightening around the eyes. This is a great preventative product and lasts awhile.
0 people found this helpful
LovelySkin Customer
from North Carolina
Age Group: 40-49
Straight hair, Damage & split ends
Normal Skin
Verified Purchase
i ended up buying this after getting a couple samples. it was an instantaneous difference in my skin. it’s a staple in my night time and day time regimen now!
0 people found this helpful
EPyer
from Tennessee
Age Group: 70-79
Straight Hair
Verified Purchase
Have only been using it for a short time but it definitely helps the feel of my skin.
1 person found this helpful
LovelySkin Customer
from Puerto Rico
Age Group: 60-69
Wavy, Color treated hair
Dry Skin
Verified Purchase
I am 66 years old and I have been using PTiox serum for almost 6 months. The skin texture has improved and the appearance of wrinkles have diminished. I am satisfied with the results.
3 people found this helpful
LovelySkin Customer
from Puerto Rico
Age Group: 60-69
Straight Hair
Mature Skin
Verified Purchase
Along with the cream is a game changer! After only 1 week my skin looks better, more radiant. Can't wait for a long term results.
3 people found this helpful
Orangetangerine
from Puerto Rico
Age Group: 30-39
Wavy Hair
Combination Skin
Verified Purchase
I will permanently buy this (until they change the formulation or discontinue) because this is literally a game changer for me. I can see how hydrated and glowy my skin looks after using this. Unfortunately the price is a bit steep for me, hence the 4 stars.
6 people found this helpful
LovelySkin Customer
from Florida
Age Group: 30-39
Verified Purchase
This product has been a great addition to my skin care routine. It’s smooth and soaks right into my face nicely!
2 people found this helpful
Molecule
from Arizona
Mature Skin
Verified Purchase
I love Skinceutical products! This serum goes on easy and paired with the P-Tiox cream, it leaves my skin feeling like smooth silk. I have used Skinceutical products for several years and they all are wonderful! I've tried other brands and always returns to Skinceutical products. I won't be buying anything else from now on. Their products last a long time and you don't have to use a lot for great results.
3 people found this helpful
GoJo
from Illinois
Age Group: 70-79
Mature Skin
Verified Purchase
In just a little over a week I can see this product is making a huge difference!
8 people found this helpful
Dovey
from Pennsylvania
Age Group: 60-69
Straight, Color treated hair
Dry Skin
Verified Purchase
This is the best serum I’ve found for my aging skin. Results for me are usually subtle, but with P-TIOX I saw a very noticeable improvement in lines and wrinkles as well as a more refined texture. I follow it with Skinceuticals A.G.E. Interrupter cream at night.
13 people found this helpful
SM28
from Puerto Rico
Age Group: 30-39
Oily Skin
Verified Purchase
The hype on this product is real!! Too pricey for what is says to achieve. I do use retinol and other products so I can’t really tell or say honestly that this does help with fine lines or wrinkles because I haven’t seen any results from one bottle. I do like the glow I have in the morning from it and it does leave this healthy shine, but that’s not the point to spend this nuch money.
10 people found this helpful
LovelySkin Customer
from Florida
Age Group: 70-79
Curly, Color treated hair
Combination Skin
Verified Purchase
Tried the SkinCeuticals P-TIOX Wrinkle Modulating Peptide Serum but not impressed enough with the results to reorder. You can only layer two or three treatment products on your face and there are more effective serums on the market than this one.
13 people found this helpful
Marsh
from North Carolina
Verified Purchase
I have been using this in complete with the cream and my skin looks good and I can tell a difference
6 people found this helpful
CMN
from Washington
Age Group: 40-49
Normal Skin
Verified Purchase
I’m loving this stuff. It’s making my skin so soft and smooth. Gentle yet so very effective. I highly recommend
8 people found this helpful
LovelySkin Customer
Verified Purchase
I have sensitive, redness prone, normal-to-dry skin with acne rosacea. P-TIOX didn't work as well as expected and caused crepiness and acne.
16 people found this helpful