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SkinCeuticals P-TIOX Wrinkle Modulating Peptide Serum

Reviews For SkinCeuticals P-TIOX Wrinkle Modulating Peptide Serum

$150.00
249 Reviews
November 28, 2025

SkinCeuticals P-TIOX Wrinkle Modulating Peptide Serum

Thank you Lovely Skin for introducing this product! SkinCeuticals hit it out of the park with P-TIOX. It is quickly becoming one of the staples in their line. It already is a staple in my skin care. I love how smooth and glasslike this product makes my mature skin. It plays well with all other products! I use it under moisturizer and tinted sunscreen/foundation. I've also been able to stack this serum with hyaluronic acid, moisturizer, finishing with tinted sunscreen/foundation. I feel good about treating my skin with this peptide serum.

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LovelySkin Customer

from Texas

Verified Purchase

1 person found this helpful

November 28, 2025

Wow

I started getting botox injections when I was 36. I cannot say that this serum can replace my botox t/x, but i can say my results last longer. My skin also has tightened and shown quite a difference in my marionette lines (I hate those). Yes this serum is expensive, but 3 drops and you're good. I typically use it once daily due to the cost. 2 nights a week I will apply it under my retinol. In the morning I apply it after my vitamin C serum. It's just a really good product.

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LovelySkin Customer

from Pennsylvania

Age Group: 40-49

Straight, Color treated hair

Oily Skin

4 people found this helpful

November 24, 2025

Smooth and soft

I’ve used this before and recently added back into my routine. Glad I did. My face feels so smooth and soft. Winner! I recommend trying!

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BethAnn

from Wisconsin

Age Group: 50-59

Verified Purchase

5 people found this helpful

November 21, 2025

Wrinkle Remover

Great product! Works well on skin around eyes an mouth

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SYM

from South Carolina

Age Group: 60-69

Wavy, Dry Hair

Combination Skin

Verified Purchase

2 people found this helpful

November 20, 2025

A Secret sauce

I was skeptical of this product, but I really do feel like there is an improvement in my skin, It helps give a little bit of that glass skin look and seems to be working, in conjunction with neurotoxin injectable treatments, to give my skin a smoother look.

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momincharge

from Connecticut

Age Group: 60-69

Combination Skin

Verified Purchase

3 people found this helpful

November 19, 2025

Jury is still out

I was going to return this but figured I would finish the bottle to decide if I like it. Honestly I am still undecided . My skin looks good but I definitely do not see any reduction in fine lines .. maybe I am too old for this 59.

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Hdhd

from Connecticut

Age Group: 50-59

Verified Purchase

4 people found this helpful

November 17, 2025

Excellent product value for your money

This is my second purchase of TIOX skin, Celsius , I really like this product. It’s a very good serum. I noticed an improvement on my skin right away after just one or two uses.it goes on smooth and a small amount goes a long way , and lasts. I think this product is good value for the money, I have used a lot of other expensive serums that have cost a lot more and not being as effective. I would definitely recommend this product.

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MMMDB

from Washington

Verified Purchase

1 person found this helpful

November 12, 2025

Overpriced and overhyped

This sounded good, but it did absolutely nothing for my mature skin. Maybe it works best on younger skin? I wish people who write the reviews would include their age. Actually, that should be a requirement! That way you can get a good idea of who benefits the most from this product. Also, make sure to read the fine print below the images (I didn't) before making your decision. The disclosure beneath the 4 photos says the protocol was "a 12-week single center clinical study" that was "conducted on 82 females with Fitzpatrick type I-VI ages 34-65 and and mild to moderate wrinkles." BUT a different disclosure under the heading "Proven Results" says the study was conducted on 75 women ages 25-55. Which is it? In any case, it is a very small study -- one single center and less than 100 people. Not robust enough, in my opinion. Also, how long does one bottle last? They don't say. So, you might have to buy at least 2 bottles, possibly more to MAYBE see results? Not a good bet. Needless to say, I will not be buying this again.

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LovelySkin Customer

Age Group: 60-69

Mature Skin

Verified Purchase

19 people found this helpful

October 25, 2025

Wow

Makes your skin look smooth and healthy

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Flowers

from New York

Verified Purchase

2 people found this helpful

October 09, 2025

Game changer!

Use a lot of SkinCeutical products but when I added this one I couldn’t believe the quick results. Fine lines and skin texture improved within a week; and I already have flawless skin. Go buy and couple with their C E Ferulic Acid and multi-glycon intensifying volumizing serum. Magic!!! Use CE Ferulic first then P-Tiox and then Multi-Glycon!!!

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Valerie

from California

Verified Purchase

8 people found this helpful

October 04, 2025

Permanent Part of Daily Routine

I prefer simple and streamlined routines, but as I age, I’ve been adding more and more steps to my daily skincare. I recently added this in the am, after a gentle cleanser. I love how quickly the serum absorbs into my skin. Next, I apply a moisturizer, eye cream, and a sunscreen and I am ready to go. While the price is a bit high, a little goes a long way.

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LynnMF

from Virginia

Age Group: 50-59

Straight hair, Damage & split ends

Combination Skin

Verified Purchase

5 people found this helpful

October 02, 2025

Pleasantly surprised

I was told about this product by my aesthetician but wasn’t sure about adding another serum to my regimen. When I first started using the serum, I felt like it made my skin dry but that had gotten better in time. My skin does look a little better but I’m still not sure it’s worth the cost.

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Koliver

from Nebraska

Age Group: 40-49

Combination Skin

Verified Purchase

10 people found this helpful

September 27, 2025

Makes a significant difference.

My dermatologist suggested this serum as a way to lengthen filler results. Have only been using it a few months so too early to be sure, but it does seem to extend the filler effects. What is more evident is its smoothing effect, I was not exactly sure what ‘glass skin” meant before but now I do. My skin’s surface seems a bit glowing and less porous - but not shiny. Make up goes on easier and even seems to come off easier, with no tightness. I have very sensitive skin so only use it at night. May try to alternate with my go to C&E serum in the morning. This serum seems different than anything else I’ve used and I am very happy with it. Of course wish it were less expensive.

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LovelySkin Customer

from New York

Verified Purchase

8 people found this helpful

September 26, 2025

nice serum so far

This serum sinks in fast, layers cleanly with vitamin C and retinol, and gives an immediate, subtle glow without stickiness. After three to four weeks, my forehead and marionette lines looked a touch softer and pores appeared tighter, especially paired with HA at night. It makes makeup sit better and skin look smoother day to day. I'll probably buy it once more to see what happens after using it for a longer period and then decide whether the results justify the investment to keep it in the permanent rotation.

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LovelySkin Customer

from Pennsylvania

Age Group: 40-49

Combination Skin

Verified Purchase

10 people found this helpful

September 21, 2025

Just okay

I did not really see any difference using this product. In fairness I do not do any injections so I can't speak to how it may work if your are maintaining from doing office procedures. It is a very good brand so could be worth a try for some as everyone's skin is different.

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LovelySkin Customer

from Texas

Age Group: 50-59

Verified Purchase

9 people found this helpful

September 15, 2025

Worth Trying

I’ve finished my first bottle of SkinCeuticals P-TIOX Wrinkle Modulating Peptide Serum. And have ordered another ! I didn’t expect to see major changes on my 74 year old face - but certainly enough to want to continue!

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LovelySkin Customer

from Florida

Age Group: 70-79

Mature Skin

Verified Purchase

15 people found this helpful

September 15, 2025

Needed more

I had hoped more wrinkles would have been helped. Maybe not clear what fine wrinkles are. Mine are deep in my cheeks.

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LovelySkin Customer

from Massachusetts

Age Group: 70-79

Verified Purchase

9 people found this helpful

September 12, 2025

Haven't noticed a difference

I haven't been able to use this consistently due to having microneedling done, but I did for a couple weeks before starting the treatments and didn't see any difference in my skin. Maybe it takes longer to work.

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sandytp1

from Iowa

Age Group: 70-79

Mature Skin

Verified Purchase

7 people found this helpful

September 06, 2025

So far so good!

Been using for a month or so and so far so good! Would buy again

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LovelySkin Customer

Verified Purchase

3 people found this helpful

September 05, 2025

LOVE!

Only been using it for about 3 weeks and can already tell a difference

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Skincarexprt

from New York

Age Group: 40-49

Combination Skin

Verified Purchase

0 people found this helpful


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