Inspired by the effects of neurotoxin injections, this serum is formulated with an Advanced Peptide Complex and a Glass Skin Complex to smooth nine types of contraction and expression lines to rejuvenate skin for a renewed glow. Neurotoxin injections are a popular in-office treatment used to treat expression wrinkles caused by muscle contractions.
When paired together, P-TIOX and neurotoxin injections work synergistically to help reduce the appearance of wrinkles, delivering fast, long-lasting results. Versatile and innovative, this serum is also effective on its own to smooth skin, refine pores and reveal glass skin radiance in one week of use.
Clinical Results:
Key Features:
Free U.S. Shipping. Period. View Our Shipping Policy
Return Policy: View Our Return Policy
Availability: In stock & ready to ship! . Ships within the U.S. only.
Submit your question about this product to our talented team of Customer Care Representatives, and we'll get back to you as soon as possible!
You can receive 50 rewards points by sharing your honest opinion of SkinCeuticals P-TIOX Wrinkle Modulating Peptide Serum.
Filtered by: Clear Filters
249 Reviews
LovelySkin Customer
from Texas
Verified Purchase
Thank you Lovely Skin for introducing this product! SkinCeuticals hit it out of the park with P-TIOX. It is quickly becoming one of the staples in their line. It already is a staple in my skin care. I love how smooth and glasslike this product makes my mature skin. It plays well with all other products! I use it under moisturizer and tinted sunscreen/foundation. I've also been able to stack this serum with hyaluronic acid, moisturizer, finishing with tinted sunscreen/foundation. I feel good about treating my skin with this peptide serum.
1 person found this helpful
LovelySkin Customer
from Pennsylvania
Age Group: 40-49
Straight, Color treated hair
Oily Skin
I started getting botox injections when I was 36. I cannot say that this serum can replace my botox t/x, but i can say my results last longer. My skin also has tightened and shown quite a difference in my marionette lines (I hate those). Yes this serum is expensive, but 3 drops and you're good. I typically use it once daily due to the cost. 2 nights a week I will apply it under my retinol. In the morning I apply it after my vitamin C serum. It's just a really good product.
4 people found this helpful
BethAnn
from Wisconsin
Age Group: 50-59
Verified Purchase
I’ve used this before and recently added back into my routine. Glad I did. My face feels so smooth and soft. Winner! I recommend trying!
5 people found this helpful
SYM
from South Carolina
Age Group: 60-69
Wavy, Dry Hair
Combination Skin
Verified Purchase
Great product! Works well on skin around eyes an mouth
2 people found this helpful
momincharge
from Connecticut
Age Group: 60-69
Combination Skin
Verified Purchase
I was skeptical of this product, but I really do feel like there is an improvement in my skin, It helps give a little bit of that glass skin look and seems to be working, in conjunction with neurotoxin injectable treatments, to give my skin a smoother look.
3 people found this helpful
Hdhd
from Connecticut
Age Group: 50-59
Verified Purchase
I was going to return this but figured I would finish the bottle to decide if I like it. Honestly I am still undecided . My skin looks good but I definitely do not see any reduction in fine lines .. maybe I am too old for this 59.
4 people found this helpful
MMMDB
from Washington
Verified Purchase
This is my second purchase of TIOX skin, Celsius , I really like this product. It’s a very good serum. I noticed an improvement on my skin right away after just one or two uses.it goes on smooth and a small amount goes a long way , and lasts. I think this product is good value for the money, I have used a lot of other expensive serums that have cost a lot more and not being as effective. I would definitely recommend this product.
1 person found this helpful
LovelySkin Customer
Age Group: 60-69
Mature Skin
Verified Purchase
This sounded good, but it did absolutely nothing for my mature skin. Maybe it works best on younger skin? I wish people who write the reviews would include their age. Actually, that should be a requirement! That way you can get a good idea of who benefits the most from this product. Also, make sure to read the fine print below the images (I didn't) before making your decision. The disclosure beneath the 4 photos says the protocol was "a 12-week single center clinical study" that was "conducted on 82 females with Fitzpatrick type I-VI ages 34-65 and and mild to moderate wrinkles." BUT a different disclosure under the heading "Proven Results" says the study was conducted on 75 women ages 25-55. Which is it? In any case, it is a very small study -- one single center and less than 100 people. Not robust enough, in my opinion. Also, how long does one bottle last? They don't say. So, you might have to buy at least 2 bottles, possibly more to MAYBE see results? Not a good bet. Needless to say, I will not be buying this again.
19 people found this helpful
Flowers
from New York
Verified Purchase
Makes your skin look smooth and healthy
2 people found this helpful
Valerie
from California
Verified Purchase
Use a lot of SkinCeutical products but when I added this one I couldn’t believe the quick results. Fine lines and skin texture improved within a week; and I already have flawless skin. Go buy and couple with their C E Ferulic Acid and multi-glycon intensifying volumizing serum. Magic!!! Use CE Ferulic first then P-Tiox and then Multi-Glycon!!!
8 people found this helpful
LynnMF
from Virginia
Age Group: 50-59
Straight hair, Damage & split ends
Combination Skin
Verified Purchase
I prefer simple and streamlined routines, but as I age, I’ve been adding more and more steps to my daily skincare. I recently added this in the am, after a gentle cleanser. I love how quickly the serum absorbs into my skin. Next, I apply a moisturizer, eye cream, and a sunscreen and I am ready to go. While the price is a bit high, a little goes a long way.
5 people found this helpful
Koliver
from Nebraska
Age Group: 40-49
Combination Skin
Verified Purchase
I was told about this product by my aesthetician but wasn’t sure about adding another serum to my regimen. When I first started using the serum, I felt like it made my skin dry but that had gotten better in time. My skin does look a little better but I’m still not sure it’s worth the cost.
10 people found this helpful
LovelySkin Customer
from New York
Verified Purchase
My dermatologist suggested this serum as a way to lengthen filler results. Have only been using it a few months so too early to be sure, but it does seem to extend the filler effects. What is more evident is its smoothing effect, I was not exactly sure what ‘glass skin” meant before but now I do. My skin’s surface seems a bit glowing and less porous - but not shiny. Make up goes on easier and even seems to come off easier, with no tightness. I have very sensitive skin so only use it at night. May try to alternate with my go to C&E serum in the morning. This serum seems different than anything else I’ve used and I am very happy with it. Of course wish it were less expensive.
8 people found this helpful
LovelySkin Customer
from Pennsylvania
Age Group: 40-49
Combination Skin
Verified Purchase
This serum sinks in fast, layers cleanly with vitamin C and retinol, and gives an immediate, subtle glow without stickiness. After three to four weeks, my forehead and marionette lines looked a touch softer and pores appeared tighter, especially paired with HA at night. It makes makeup sit better and skin look smoother day to day. I'll probably buy it once more to see what happens after using it for a longer period and then decide whether the results justify the investment to keep it in the permanent rotation.
10 people found this helpful
LovelySkin Customer
from Texas
Age Group: 50-59
Verified Purchase
I did not really see any difference using this product. In fairness I do not do any injections so I can't speak to how it may work if your are maintaining from doing office procedures. It is a very good brand so could be worth a try for some as everyone's skin is different.
9 people found this helpful
LovelySkin Customer
from Florida
Age Group: 70-79
Mature Skin
Verified Purchase
I’ve finished my first bottle of SkinCeuticals P-TIOX Wrinkle Modulating Peptide Serum. And have ordered another ! I didn’t expect to see major changes on my 74 year old face - but certainly enough to want to continue!
15 people found this helpful
LovelySkin Customer
from Massachusetts
Age Group: 70-79
Verified Purchase
I had hoped more wrinkles would have been helped. Maybe not clear what fine wrinkles are. Mine are deep in my cheeks.
9 people found this helpful
sandytp1
from Iowa
Age Group: 70-79
Mature Skin
Verified Purchase
I haven't been able to use this consistently due to having microneedling done, but I did for a couple weeks before starting the treatments and didn't see any difference in my skin. Maybe it takes longer to work.
7 people found this helpful
LovelySkin Customer
Verified Purchase
Been using for a month or so and so far so good! Would buy again
3 people found this helpful
Skincarexprt
from New York
Age Group: 40-49
Combination Skin
Verified Purchase
Only been using it for about 3 weeks and can already tell a difference
0 people found this helpful
