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SkinMedica’s cutting-edge formulations help you rejuvenate and maintain healthy skin.

A bottle of SkinMedica TNS Advanced+ Serum laying flat

Shop SkinMedica products

SkinMedica’s cutting-edge formulations help you rejuvenate and maintain healthy skin.

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SkinMedica TNS Advanced+ Serum with new dual-pump design

This award-winning formula now features smarter, more stylish packaging with a dual-pump system that ensures consistent, precise delivery for beautiful results every time.

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20% off SkinMedica & 20% off Replenishment

For a limited time, enjoy special savings on fan-favorite formulas designed to help rejuvenate skin with every drop.

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Featured SkinMedica Reviews

4.6 of 5 stars
Based on 1932 reviews
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Most Recent Review

10
Mar 19, 2026

Holy Grail of Holy Grails

as someone who already has all the skincare essentials, including daily tretinoin, vitamin c, and spf, i didn't think there was much room for improvement. i was wrong. the tns advanced+ serum is the …

Product Review Summary

Most Recent Review

10
Mar 20, 2026

Great product

Keeps skin moist but not greasy. I use every morning and night. Wrinkles have softened too! Yea!

Product Review Summary

4.8 of 5 stars
Based on 699 reviews
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Most Recent Review

10
Mar 18, 2026

My new favorite!

I've been looking for an exfoliating cleanser since Obagi and Kinetin discontinued theirs, and this SkinMedica is perfect! I'm so glad I tried it, and will continue to buy it again.

Product Review Summary


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