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iS CLINICAL Youth Intensive Creme

1.7 oz / 50 ml
| HSA|FSA Eligible LMN Required
$246.00
Highlights
  • Contains antioxidants
  • Paraben-free
  • Provides intense hydration
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Product Overview

iS CLINICAL Youth Intensive Creme helps you achieve a younger-looking complexion.

This extraordinarily rich and luxurious anti-aging formula helps to reduce the appearance of fine lines and wrinkles as it provides powerful hydration. This transformative crème scientifically combines the purest and most effective botanically-derived moisturizers, antioxidants, resurfacing acids, and copper peptide growth factors to help you achieve your youngest-appearing skin yet.

Clinical Results based on 4-week clinical study conducted by BioScreen Clinical Service:

  • 43% increase in skin tone in four weeks
  • 100% increase in skin hydration in one day
  • 77% increase in skin firmness in four weeks

Key Features: 

  • Rapidly smooths skin, revealing a firmer and more radiant complexion
  • Copper tripeptide-1 visibly reduces wrinkles over time
  • Superoxide dismutase, an antioxidant-rich enzyme, protects against visual effects of photodamage 
  • Vitamin C provides antioxidant protection while brightening skin 

Highlights

  • Contains antioxidants
  • Paraben-free
  • Provides intense hydration

Ingredients

Directions

Shipping & Returns

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Special Shipping Requirements: ORM-D Class
ORM-D classified products such as aerosol sprays, nail polish, perfume and products with high alcohol content may only be shipped using a ground method within the Continental US.

Availability: In stock & ready to ship! . Ships within the U.S. only.

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Product Specifications

About the Brand

Customer Reviews (48)

Overall Rating

4.6
Based on 48 reviews

Review Summary

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48 Reviews

Profile picture of KBCohen.

KBCohen

Verified Purchase

June 19, 2025

Smooth and Creamy

LOVE this cream for nightime use. You only need a small amount to get Amazing results!!

0 people found this helpful

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LovelySkin Customer

Verified Purchase

May 17, 2025

Effective but has a very strong scent

This product is effective in keeping my skin moisturized. However, the scent is very strong. If you can tolerate strong scents, then I do highly recommend this product for evening use. It is not greasy but very thick for those who have very dry skin.

0 people found this helpful

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Betterthanbotox

Verified Purchase

April 01, 2025

Amazing

I love this face cream. This is such a clean feeling not greasy at all. I like to use it in the morning under my makeup and in the evening before bed. Speedy but worth every penny.

2 people found this helpful

Profile picture of MinnMNman.

MinnMNman

Verified Purchase

October 05, 2024

Turn back the clock!

Smaller pores, firmer smoother skin and mouthwatering hydration is what this cream provides. I've used everything on the market and this is the one! All of this and a fragrance that is just short of addictive. The price is high, but I only have one face.

4 people found this helpful

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LovelySkin Customer

Verified Purchase

June 29, 2024

Nice cream

I really like this cream, It is light weight and moisturizing. I just think it has gotten too expensive. Other less expensive products deliver the same results.

3 people found this helpful

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PB317

Verified Purchase

June 24, 2024

Absolutely amazing

This cream is pricey but worth it! We live in Colorado and I could immediately see a difference in the hydration of my skin. It deeply moisturizes and leaves my skin incredibly soft.

0 people found this helpful

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LovelySkin Customer

Verified Purchase

January 24, 2024

Pricey but wonderful

I've wanted to try it for years but have held off. Now that I'm using it I think it will be hard to switch to something else. It smells amazing and goes on like a cloud. Very high quality. Comes with a metal scoop to reduce finger contamination. You don't need a lot of product! One vial lasts me 3-4 months, but I do put it on my neck as well, so you may be able to get more months out of it.

0 people found this helpful

Profile picture of RoJo.

RoJo

Verified Purchase

December 28, 2023

It really works wonders!

Many face creams just don't moisturize enough in the harsh winter climate. iS Clinical Youth Intensive Creme really works wonders. I apply at night and wake up with plump and healthy looking skin. Apply sparingly as a little goes a long way. It's worth the price and will last.

2 people found this helpful

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LovelySkin Customer

Verified Purchase

December 18, 2023

Amazing for dry climate

This product has absolutely helped keep my skin hydrated in very dry climates. I feel that it also helps with fine lines and keeps my skin looking plump, even in the winter!

0 people found this helpful

Profile picture of COM.

COM

Verified Purchase

September 14, 2023

Love, love love it

This is my favorite night time moisturizer. My skin feels so dewy in the morning. I use it every time. It's expensive but it's best I e found.

1 person found this helpful

Profile picture of Jacqui.

Jacqui

Verified Purchase

August 25, 2023

Wonderful creme

I'm a big fan of IS CLINICAL and this creme is no exception. I've been using it for a couple of months and I can see a difference in the clarity and hydration of my skin. It's also helped refine the overall look of my skin. I would highly recommend.

1 person found this helpful

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LovelySkin Customer

Verified Purchase

June 27, 2023

Pricey creme

A dermatologist recommended this product. It is very pricey so I use is sparingly. It is just ok for the price.

0 people found this helpful

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LovelySkin Customer

Verified Purchase

June 24, 2023

I love it

Is Clinical YOUTH INTENSIVE CREME is working great on my skin. My skin looks gorgeous!! I highly recommend it.

1 person found this helpful

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LovelySkin Customer

Verified Purchase

April 16, 2023

Firmed, but dried my skin

Ii have been very pleased with IS Clinical products and was excited to try this one. My sensitive, age 74 skin has not responded well to this cream. It HAS had a firming effect, but unfortunately, it has also had a drying effect, leaving laugh lines, etc looking more pronounced.

0 people found this helpful

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LovelySkin Customer

Verified Purchase

April 11, 2023

The best cream

I’ve tried all the creams and this one is my favorite. The texture is like velvet and I’ve really noticed a difference in my skin. I originally sought it out because it contains superoxide dismutase which combats oxidative stress. My skin is brighter and more plump. I wish it were a little less pricey!

1 person found this helpful

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Honeyglow

Verified Purchase

March 21, 2023

Like A.G.E interrupted but better

I used to be a huge fan of A.G.E interrupter but I over did it ok harsh products and my skin got very angry. My normal moisturizer wasn’t cutting it at all. I already have dry skin but I thought i would sacrificed a bit of moisture for the long term benefit.. this cream in very near the same without the moisture sacrifice. It’s literally the best cream I’ve ever used. I’ve never met a moisturizer that I had to use such a small amount to achieve relief and any type of glow.. until this one. Worth the splurge 10000% - literally the moisturizer I hoped many other “expensive” brand would be.

2 people found this helpful

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LovelySkin Customer

Verified Purchase

March 13, 2023

looks posh

The package looks very posh with a little metal spoon inside, I like dense texture of the cream and the way it smells. I just started using it so can't say anything yet about long-term results, but it feels nice and smooth on the face.

0 people found this helpful

Profile picture of Churlgurl.

Churlgurl

Verified Purchase

February 19, 2023

Love it!

I bought the full size Youth Intensive Creme after receiving a sample with another purchase. Using the sample just once plumped by wrinkles and lines, and kept my face moisturized all day. This creme easily blends onto your skin using a small amount. Love it.

2 people found this helpful

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LovelySkin Customer

Verified Purchase

January 01, 2023

Very moisturizing

Great for dry cold winters! Used with the serum and is amazing!

1 person found this helpful

Profile picture of Ptsep.

Ptsep

Verified Purchase

November 08, 2022

My holy grail cream

This is a moisturizer that I always come back to. It has all the scientifically proven ingredients that I look for and often cannot find together in one product. The skin on my neck and face are softer and have less lines when I use this cream regularly. My skin's youthful look keeps me buying this cream. I use this last in my evening facial routine.

1 person found this helpful

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