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ISDIN Isdinceutics Melatonik Lightweight Night Serum with Bakuchiol

1.0 fl oz
| HSA|FSA Eligible LMN Required
$175.00

Special Offer: 30% off use code BFS25

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Highlights
  • Revitalizes skin's appearance with vitamin C
  • Bakuchiol addresses signs of aging
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Product Overview

ISDIN Melatonik Lightweight Night Serum with Bakuchiol stimulates skin's natural antioxidant defenses to counter dehydrated skin and sun damage.

This restorative overnight serum-in-oil redfines "beauty sleep" and helps skin recover from daily stresses that can lead to sun damage, fine lines and wrinkles and loss of firmness and elasticity. This vitamin C and melatonin serum also contains bakuchiol, stimulates natural antioxidant defenses and helps to restore vitality and elasticity for radiant, healthy skin.

Key Features:

  • Melatonin acts as an indirect antioxidant, stimulating skin's natural defenses
  • Bakuchiol, an all-natural alternative to retinol, restores elasticity and firmness
  • Vitamin C brightens skin and boosts collagen production

Highlights

  • Revitalizes skin's appearance with vitamin C
  • Bakuchiol addresses signs of aging
  • Melatonin protects skin from free radicals

Ingredients

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Availability: In stock & ready to ship! . Ships within the U.S. only.

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Product Specifications

Customer Reviews (38)

Overall Rating

4.6
Based on 38 reviews

Review Summary

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38 Reviews

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LovelySkin Customer

from California

Age Group: 40-49

Dry Skin

Verified Purchase

December 04, 2025

Wonderful retinol alternative

I have sensitive, rosacea prone skin and can’t tolerate retinol. This is a fantastic alternative to that. It has a lovely light fragrance and a little goes a long way. My skin drinks it in, and I get compliments on my skin regularly. I have used this as my night serum for over 1.5 years and will continue to purchase-worth the money.

0 people found this helpful

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Kellyhill

from Michigan

Age Group: 40-49

Wavy Hair

Combination Skin

Verified Purchase

September 26, 2025

Moisturizing glow!

I love this serum after I cleanse at night. A little goes a long way for sure. I am on my second bottle and think it’s the best night serum I’ve used. It’s lightweight enough where I even mix it with a little retinol-based cream. Ever since my medspa explained how good backuchiol is for my skin, I can’t imagine not using it!

0 people found this helpful

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Denverlady8

from Colorado

Age Group: 50-59

Verified Purchase

September 24, 2025

Love, love, love Isdin Melatonik

This serum is light and smells great. It absorbs quickly onto my face and instantly makes my face so soft and smooth. In the am, you feel and see the difference. It's pricey but well worth it. This product is a keeper and my favorite Isdin product!

0 people found this helpful

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Tekhouse

from Texas

Age Group: 60-69

Curly, Color treated hair

Mature Skin

Verified Purchase

August 18, 2025

Great serum for sensitive skin

I was very pleased with this product. The serum is lightweight as advertised. It helps diminish fine lines and even out skin tone. I have very sensitive skin and I am able to use this with no problem.

2 people found this helpful

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ninman

from Virginia

Age Group: 50-59

Straight, Color treated hair

Dry Skin

Verified Purchase

July 29, 2025

Great product - excellent results

Love this product. Not too heavy, and leaves my skin smooth and with minimized lines. Most noticeable on forehead.

0 people found this helpful

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LovelySkin Customer

Verified Purchase

July 05, 2025

iSIDN user!

This is an awesome addition to anyone’s nightly skin care routine I use it first no matter what ! Then I proceed with my SkinCeutical “ night-time” routine This works great for me…..77 We women must figure it out for our age and skin!!!

2 people found this helpful

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LovelySkin Customer

Verified Purchase

June 09, 2025

Skin is glowing and brighter

Skin is brighter and smoother when you apply it at night. Smell is so good and relaxing to me. Highly recommend! Must have skin care routine at night.

1 person found this helpful

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Marshie

Verified Purchase

June 09, 2025

Good Serum

Absorbs quickly. A little goes a long way. Makes your skin feel great. Haven’t been using it long enough to notice any reduction in fine lines and wrinkles but overall my skin looks and feels terrific.

0 people found this helpful

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LovelySkin Customer

Verified Purchase

June 04, 2025

So far, OK

Lovely texture and scent. I've been using this serum as directed for only a few weeks and so far I'm not seeing any skin improvements that merit its price. Perhaps those are still to come.

1 person found this helpful

Profile picture of HCM.

HCM

Verified Purchase

May 12, 2025

Good for Sensitive Skin

My Dermatologist recommended this line of products due to my older, sensitive skin. I have seen an excellent improvement in smoothness, texture and skin clarity. Highly Recommend this product.

1 person found this helpful

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MMMD

Verified Purchase

May 04, 2025

Great for dry skin

Been using for years. So happy to see this product now available at Lovely Skin. Hydrating and smoothing for dry skin. A little goes a long way.

0 people found this helpful

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LovelySkin Customer

Verified Purchase

May 03, 2025

Mild retinol

Love this mild retinol. I use different levels of retinol at various times but love to travel with this one because it’s easy to use and I love the glow I get from it. The fragrance is lovely too.

1 person found this helpful

Profile picture of Bell.

Bell

Verified Purchase

April 08, 2025

Amazing!

This is the night serum that I have been waiting for! I wake up and my skin is fully hydrated. Clear formula goes on easily. Gently locks in moisture all night.

0 people found this helpful

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LovelySkin Customer

Verified Purchase

February 11, 2025

Customer

Excellent night product, prepares skin for moisturizer.

0 people found this helpful

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FernNC

Verified Purchase

January 29, 2025

Dryed out my skin

I received this as a sample & absolutely loved using it in my nighttime routine so I ordered a full bottle. After about 2 weeks my face was dry and flaky. After process of elimination I determined it to be from this product. I stopped using it and my face got back to normal. I do not have sensitive skin nor have I reacted to any other products I've tried. Maybe this was a fluke but I wanted to provide my honest review.

5 people found this helpful

Profile picture of Lovelyskinat60.

Lovelyskinat60

Verified Purchase

January 28, 2025

Love this Serum!

After trying a free sample, I decided to purchase this serum. While I can't quite tell if it's made a definitive difference in my overall skin tone and/or quality, I can say that I love the experience right after applying this product with respect to the warmth and softness of my skin, which seems to last until morning. It may take a bit to determine the long term effectiveness, but for now, my review is very positive.

0 people found this helpful

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Tricia

Verified Purchase

January 10, 2025

Melatonin lightweight night serum

This is an excellent defense serum that protects the skin and renews the texture and elasticity

0 people found this helpful

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CherG

Verified Purchase

December 13, 2024

Excellent Serum

I love this serum. It soaks right into my skin. I have used this alone at night and my skin is so soft the next day.

0 people found this helpful

Profile picture of Spaskin.

Spaskin

Verified Purchase

December 06, 2024

Beautiful Serum!

What a powerful serum! Just a few drops each night, and your skin will thank you! Received as a sample, and I became hooked. Bought the full size as soon as I could! The scent is light and the serum soaks right in to make your face feel smooth and supple.

0 people found this helpful

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DJ522

Verified Purchase

November 28, 2024

Great Product

I rarely give 5 star reviews, but this serum definitely deserves it. It may not be for everyone, but I love the texture. It feels like it has just a touch of oil, which is absorbed quickly. I haven't been using it for very long, so I can't rate the long-term impact. But so far so good. I really look forward to using it each night.

0 people found this helpful

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