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ISDIN ISDINCEUTICS Retinal Advanced Serum
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ISDIN Isdinceutics Retinal Advanced Dual-Phase Night Serum

1.7 fl oz
4.7 View 33 reviews
$185.00
Highlights
  • Suitable for all skin types
  • Brings back elasticity and firmness
  • Hydrates and calms skin with a soothing complex
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Product Overview

ISDIN Isdinceutics Retinal Advanced Dual-Phase Night Serum visibly smooths while you sleep.

This nighttime treatment features dual-phase technology. While in the bottle, the treatment exists as two different serums, a more emollient one with retinaldehyde and a lighter one with a soothing complex. They combine right when you use the treatment to keep the retinaldehyde potent and create a lovely texture.

Clinical Results (One Month):

  • 43% reduction in wrinkles

Consumer Results (Three Months):

  • 90% observed renewed skin
  • 97% observed firmer skin
  • 97% observed no discomfort
  • 97% observed a reduction of wrinkles and fine lines

Key Features:

  • Reduces visible wrinkles in just one month
  • Addresses discoloration and redness with niacinamide
  • Combines 0.1% retinaldehyde with bakuchiol, a natural retinol-like extract

Highlights

  • Suitable for all skin types
  • Brings back elasticity and firmness
  • Hydrates and calms skin with a soothing complex

Ingredients

Directions

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Product Specifications

Customer Reviews (33)

Overall Rating

4.7
Based on 33 reviews

Review Summary

5 Stars
28 reviews
4 Stars
4 reviews
3 Stars
0 review
2 Stars
0 review
1 Star
1 review

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33 Reviews

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LovelySkin Customer

Verified Purchase

May 18, 2025

My favorite night time routine

I absolutely love this product. I wake up with smooth and glowing skin. It isn't irritating as other retinols I have used in the past. I will keep using ISDIN Retinal Advanced!!

0 people found this helpful

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MariaCampos

Verified Purchase

May 12, 2025

favorite in my skincare routin

I’ve been using this retinol for a few weeks now and I’m seriously impressed. My skin feels smoother, looks more even. It’s gentle enough that I didn’t experience any major irritation, but still effective.

0 people found this helpful

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LovelySkin Customer

Verified Purchase

April 29, 2025

Love ISDIN

I love this retinal cream by ISDIN. It is not as harsh as the regular RetinA. It feels great on the skin. I like the dual chamber and it mixes well. Highly recommend especially if you cannot tolerate tretinoin/ RetinA.

1 person found this helpful

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dsnc109

Verified Purchase

February 27, 2025

Great serum

I have finally found a serum that I am in love with. This serum does what it says. I wake up with an even and smooth complexion every morning. Really has made a difference in wearing makeup too as the skin is smooth and even toned. I plan on getting some more of this even before I run out of the one I am currently using just so I won't run out.

2 people found this helpful

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ArtistAnn

Verified Purchase

February 02, 2025

Works for smoother, brighter skin

Love this product! I am in my 70s so, not a spring chick! If it works for me it will work for you!

2 people found this helpful

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LovelySkin Customer

Verified Purchase

January 11, 2025

amazing retinol

Feel like it is strong and working but does not burn like others have and can tell it is already working!

0 people found this helpful

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LovelySkin Customer

Verified Purchase

January 03, 2025

Great Retinal Serum

I had been purchasing this serum years before Lovely Skin sold the product on the advice of my dermatologist. It dispenses perfectly from the dual chambers and can then be blended on the back of my hand. One pump per night goes a long way! A great retinal option!

0 people found this helpful

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suzy

Verified Purchase

January 02, 2025

Great Serum

Helps my skin look fresher in the morning. Goes on very easily. Would prefer a single chamber dispenser, though. So far, it works fine.

0 people found this helpful

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CMC11

Verified Purchase

December 10, 2024

Great Product!

I have only been using this product for a few weeks so I haven't seen a noticeable difference yet. I have extremely sensitive skin and have a hard time with retinols. I use other ISDIN products and decided to try this one. Love the pump! I've had trouble with other brands and pumps. This one is perfect. Two pumps on my fingers, rub together and smooth over the face. I can almost feel the tingling from the start. Once it dries, I follow with moisturizer. Used every other night for a week until my skin was ready for every night. There is a little dryness/flaky skin the next day. The reason I gave it 4 stars is due to the fragrance. I don't care for it. It does dissipate within a reasonable amount of time. That won't keep me from purchasing again.

0 people found this helpful

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Spaskin

Verified Purchase

December 06, 2024

Age Reversal!

Received the Retinal Advanced as a sample, and it's made a big impact on my skin! You can feel it working the moment you apply it, and it's not drying which is a bonus! I've already noticed some dark spots lightening, and my skin is very smooth. I'm in my early 60s and this will become a forever product for me to use.

0 people found this helpful

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LovelySkin Customer

Verified Purchase

December 01, 2024

Holy Grail!

I’ve been using this product for about 3 months now. I can definitely see the difference in my skin. Very smooth textured skin now, and the wrinkle in my forehead is gone.

1 person found this helpful

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Cindyt

Verified Purchase

November 28, 2024

Advanced Dual Phase Night

This is just amazing. I use it every night before bed. It definitely helps even out your skin.

1 person found this helpful

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Kristine595

Verified Purchase

November 27, 2024

Potent yet gentle

I received a generous sized sample of this in one of my orders and absolutely LOVED it. I realize it takes time to see full results, but the aroma is so fresh, the product has two formulas, one a gentle moisturizing complex, the other retinaldehyde that disperse at one time, then you mix together (I use the palm of my hand), ensuring that the pump is pressed all the way down so they both come out in equal amounts. After application, my skin is left smooth and silky and after 6 nighttime applications, I noticed a lessening of lines and firmer, supple skin. There is no issues with burning or peeling, yet it seems very potent. I use every night before my other serums and moisturizer. I'm looking forward to continued results!

2 people found this helpful

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LovelySkin Customer

Verified Purchase

November 13, 2024

ABSOLUTELY LOVE!

This was the first ISDIN product that I tried. Received a sample from LovelySkin with a purchase. I noticed an immediate change in cell turn over and was encouraged with the was seeing with my skin, after using the product for a short time. Purchased the full size, and the rest, as they say, is history. Gentle and effective, a must have in my skin care routine! Looking forward to trying other ISDIN products

0 people found this helpful

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LovelySkin Customer

Verified Purchase

November 02, 2024

ISDIN Night Serum

I’ve just recently started using this product and so far I really like it. I love the fragrance and it makes my skin feel so smooth. I’m hoping to notice more noticeable improvement in my skin the longer I use this. I would recommend this.

0 people found this helpful

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LovelySkin Customer

Verified Purchase

October 18, 2024

Smells awful

I do not know if it rancid but I have to wash it off. I would love to return this but don’t have the box. DO NOT BUY…

1 person found this helpful

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PamelaJo

Verified Purchase

September 04, 2024

Great product

This product is really good. It never dries my skin out and it smells amazing! It truly is a luxury product!

0 people found this helpful

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Pamela

Verified Purchase

August 23, 2024

Awesome product

This product is amazing and is very easy to use. This soaks right in my skin and has helped my 66 year old ageing skin look and feel so much better. Thanks LovelySkin for carrying this product.

0 people found this helpful

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LovelySkin Customer

Verified Purchase

August 16, 2024

nice and gentle retinal product to use at night!

I am on my third bottle of this nighttime retinol--I love how gentle yet effective it is in promoting a bright, refreshed and tightened complexion in the morning. It doesn't happen overnight, give it at least a few weeks to notice a difference--but patience pays off with this product. It applies very nicely and is not sticky, absorbs quickly. When you push the bottle top it pumps out the right amount of 2 liquids that you combine on the back of your hand by mixing them together with your finger. It has definitely helped boost my collagen production, especially along my lower jaw line!

1 person found this helpful

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LovelySkin Customer

Verified Purchase

July 29, 2024

Works on sensitive skin

I have problems with tretinoin as it dries out my skin and leaves it flaky, so I tried this after a recommendation from my dermatologist and it seems to be working. I have no irritation or flaking and am hoping this will continue long term.

0 people found this helpful

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