Dermatologist owned & operated. Visit Schlessinger MD
Free 2-3 day delivery most orders, no minimums
LovelySkin
Today's Special Offer: 22% Off Friends & Family Sale + Free $28 SkinCeuticals Gift Shop Now
View more from Peter Thomas Roth

Peter Thomas Roth Peptide 21 Wrinkle Resist Serum

1.0 fl oz
This product is no longer available

We recommend the following product instead:

Highlights

  • Reduces the appearance of expression lines
  • Enhances the strength of your skin barrier
  • Free of fragrance, phthalates and parabens

You'll Love These Too!

Product Overview

Improve the appearance of fine lines and wrinkles with Peter Thomas Roth Peptide 21 Wrinkle Resist Serum.

Smooth fine lines and wrinkles with this potent anti-wrinkle serum that contains a 73% Peptide Complex, plus 2 Gamma Proteins and Asian Natto Gum to boost skin's elasticity, radiance and texture.

Formulated with:

  • Squalane: Lessens the look of fine lines and wrinkles.
  • Vitamins C, A and E: Power antioxidants that protect skin from free radical damage and encourage healthy cell turnover.
  • Hyaluronic Acid Complex: Binds moisture to the skin.

Highlights

  • Diminishes fine lines and wrinkles
  • Hydrates with hyaluronic acid
  • Antioxidants promote a more youthful appearance

Ingredients

Directions

Shipping & Returns

Free U.S. Shipping. Period. View Our Shipping Policy

Return Policy: This product is non-returnable

Return Policy: View Our Return Policy

Special Shipping Requirements: ORM-D Class
ORM-D classified products such as aerosol sprays, nail polish, perfume and products with high alcohol content may only be shipped using a ground method within the Continental US.

Availability: This product is no longer available.

Product Specifications

Customer Reviews (13)

Read all reviews
Profile picture of Janesq.

Janesq

Verified Purchase

September 12, 2023

Loved the cream, but this serum is great too

I begin my moisturizing routine with hydrating drops, follow it with Peter Thomas Roth Peptide 21 Wrinkle Resist Serum, and top it off with a triple lipid moisturizing cream. I am over 70 and find that this simple combination provides remarkable results for my face and throat (I use different creams for my eyes, of course). I had previously used the Peter Thomas Roth Peptide Lift and Firm Moisturizer and began using this serum when that product was discontinued. I highly recommend this peptide serum.

Profile picture of Pamela4.

Pamela4

December 03, 2022

Peptide Serum really plumps fine lines & wrinkles

I am so impressed with this serum. I use it after Vitamin C in the a.m. and because it is a heavy serum, I use it prior to moisturizing, in the p.m It is loaded with great ingredients like Squalane, hylauronic acid and plumping peptides like Acetyl Hexapeptide 2! I love this more than any other peptide serum. I use it on my face primarily. If I add it to my neck routine, I use a roller to help infuse the serum more deeply.

Profile picture of infomed2.

infomed2

Verified Purchase

November 26, 2022

Works as promised

I've been using this product a short while, and I can see some positive results. I use it daily, and I apply it to other areas of my face in addition to around my eyes. i.e., on my forehead and my upper lip. So far, so good! I want to note that I used Peter Thomas Roth "unwrinkle lip" cream for YEARS, and that product, sadly discontinued, was a ROCKSTAR. I wish they would bring it back!

Profile picture of LoneStarSteph.

LoneStarSteph

Verified Purchase

December 30, 2021

Just started using

So far, so good. Only been using for a few weeks but I'm hopeful to results soon.

Default profile picture.

LovelySkin Customer

Verified Purchase

December 24, 2021

A huge fan!

I love PTR products; and this is another good one. My only minor complaints are it leaves the skin a bit sticky and the bottle is so heavy, I feel it’s overkill for the less than 2 ounces of product lol. All in all, while this is a great peptide, I prefer the PCA Skin peptides. They really sink in the skin and do the job as well or better.

Profile picture of Pbspprinkle.

Pbspprinkle

Verified Purchase

September 14, 2021

Great product!

This is one of those products that you immediately feel the difference! I started using PTR products a few years ago, starting with the skin care sampler. Fell in love with those items and when I went to repurchase, saleswoman gave me a sample of the Peptide 21 line. Skin instantly feels smoother upon first application. I accompany with the Peptide 21 lotion and use at night. While I am aging, I feel like my skin is not! Add on the Peptode 21 scrub pads twice a week and alternate with the PTR PM retinol treatment for face and eyes - maybe my skin will look age 21!

Default profile picture.

LovelySkin Customer

Verified Purchase

August 01, 2021

Cause lines in my skin

Oh how I wished my skin would have loved this product. I had been wanting to try it but for some reason did not buy it until recently but it was terrible for my skin. I do not have any wrinkles or fine lines even at my age, thanks to my mother and father. (Amen to that). I always loved peptides. Makes my skin smooth but this serum made my skin oily and I got lines between my cheeks and nose which I did not have prior to using this product. Had to return it. Never again.

Profile picture of Saundra.

Saundra

Verified Purchase

June 25, 2021

In LOVE with this!

The best serum I've used! All the Peptides in one serum is worth the price. I started to receive compliments within days of use. My face looks smooth and feels soft, in LOVE with this product!

Profile picture of Cristhian.

Cristhian

Verified Purchase

May 29, 2020

In love with this product

In love with this product, have seen fewer wrinkles and expression lines!

Default profile picture.

LovelySkin Customer

Verified Purchase

April 24, 2020

Great Product

Hands down best serum I’ve used! Makes my face look so smooth and soft.

Default profile picture.

LovelySkin Customer

December 07, 2019

Amazing!

This is a wonderful serum and it shows immediate results!

Default profile picture.

LovelySkin Customer

September 04, 2019

fabulous ingredients

Wow, I have never seen so many different peptides in one serum! I guess that is why it is so expensive. Anyway, this serum is really more of a thin creamy gel. It feels moist and spreads well. it will leave your skin a tiny bit sticky, and with a very slight sheen. It has a vague soapy herbal type scent that quickly disappears.

Profile picture of Dogmom.

Dogmom

Verified Purchase

April 15, 2019

Love this!

I have great skin thanks to my parents and sunscreen. It's hard to find something that makes me noticeably look better. Within days of starting to use this I got three compliments before noon. Fantastic lotion for my skin!




Loading
Return to the top
877-754-6222
Need Help?
Email Us
Customer Care Hours
Mon - Fri 9 - 5 p.m. CT
Sat (chat only) 9 - 3 p.m. CT
Sun / Holidays Closed
Call or Text:402-697-1100