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skinbetter science AlphaRet Overnight Cream - 1.0 fl oz
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skinbetter science AlphaRet Overnight Cream

 
4.9 View 21 reviews
$145.00

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Highlights
  • Retinoid results without the irritation
  • Plumps and firms skin with peptides
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Product Overview

skinbetter science AlphaRet Overnight Cream uses a retinoid and AHA blend to visibly rejuvenate skin.

Powered by patented AlphaRet technology, this award-winning formula combines a retinoid with lactic acid to improve the look of lines, wrinkles, uneven tone and texture—with minimal irritation. A blend of peptides, ceramides and squalane helps support firmness while delivering lasting hydration for a smoother, more radiant complexion.

Key Features:

  • AlphaRet technology renews skin with less irritation than traditional retinoids
  • Ceramides, squalane and hydrating ingredients provide lasting moisture
  • Dermatologist tested and formulated without parabens, fragrances or dyes

Highlights

  • Retinoid results without the irritation
  • Plumps and firms skin with peptides
  • Promotes a healthy microbiome

Ingredients

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Product Specifications

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Customer Reviews (21)

Overall Rating

4.9
Based on 21 reviews

Review Summary

5 Stars
19 reviews
4 Stars
2 reviews
3 Stars
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21 Reviews

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LovelySkin Customer

from Florida

Age Group: 70-79

Wavy Hair

Mature Skin

Verified Purchase

November 13, 2026

Best in class

I have tried all the top retinol creams from medical based companies and this is by far my favorite. It doesn't dry out my skin and it feels silky smooth to apply.

0 people found this helpful

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LovelySkin Customer

from Minnesota

Verified Purchase

November 10, 2026

Best Retinol

This retinol is the best - does not dry out my face even when using every night. Two different estheticians recommended it to me. So glad Lovelyskin added this line!

0 people found this helpful

Profile picture of BookloverN.

BookloverN

from California

Age Group: 70-79

Wavy Hair

Mature Skin

Verified Purchase

November 07, 2026

Great product for sensitive skin

Using retinol has always been a problem for me with a lot of time taken to getting my fair, rose aprons and very sentitive skin hardened to it and having to skip days and closely monitor it and add extra layers of cream to protect it from all the retin A coming through. So retin A has just been a real headache for many years. This product is no fuss,. Goes on easily and consistency is great. I love it! I find that the dispenser cap can vary from bottle to bottle. This one Isn’t a solid at staying in place as my first one. There must just be some variation in the bottles themselves. Other than that small annoyance, I plan to be a customer of this product for life

0 people found this helpful

Profile picture of AllyOopUW.

AllyOopUW

from Washington

Age Group: 70-79

Mature Skin

Verified Purchase

November 02, 2026

Great product

I have only been using this product for about 3 weeks, but I can feel and see a slight improvement. Most importantly, I do not get any irritation from using it. I cannot wait to see more good results in the coming months!

1 person found this helpful

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LovelySkin Customer

Verified Purchase

October 21, 2026

Skinbetter AlphaRet

I love all skinbetter products and this one did not fail me. No problem with my sensitive skin!

1 person found this helpful

Profile picture of Dodi.

Dodi

from California

Age Group: 70-79

Verified Purchase

October 17, 2026

Outstanding product!

I have really sensitive skin, including periodic outbreaks of eczema and acne rosacea.i desperately need a retin- A but cannot tolerate it , even a low dose with an application every 3-4 days. So the reviews of AlphaRet included stories of users who had no outbreaks. I started with an every other night regime and am now using it every night with no bad effects. The improvement of the aging marks, etc. is not as noticeable as with the Retin-A but still noticeable. I am happy customer.

2 people found this helpful

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kpinsunnyaz

from Arizona

Age Group: 60-69

Curly, Dry Hair

Mature Skin

Verified Purchase

October 15, 2026

So far so good

I have only been using it at night for about 3 weeks but so far I like it. Doesn't irritate my skin the way prior retinol products did and it absorbs well. It does not seem moisturizing enough so I use a hydrating cream over this product. Will need more time to know if it actually does anything. I will review again once I can tell if it is worth the high price tag.

1 person found this helpful

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Reviewing

from California

Age Group: 60-69

Combination Skin

Verified Purchase

October 12, 2026

Fabulous product

Fabulous product. Works better for me than prescription retinol. Gentler, moisturizing and doesn’t clog or irritate my skin but delivers results in terms of moisture, exfoliating and smoothness. A miracle product for my sensitive easily clogged skin. Love it..

2 people found this helpful

Profile picture of MargaretMarie.

MargaretMarie

from Michigan

Age Group: 30-39

Combination Skin

Verified Purchase

September 16, 2026

Great on sensitive skin

Great if your skin is sensitive to standard retinols. I can use every night and I’m never irritated!

2 people found this helpful

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LovelySkin Customer

from California

Age Group: 30-39

Wavy Hair

Combination Skin

Verified Purchase

September 15, 2026

10/10 overnight cream

I love the Alpharet overnight cream. It gentle on my face yet works to reduce my fine lines and dark spots. Must wear sunscreen!

1 person found this helpful

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LovelySkin Customer

from Pennsylvania

Age Group: 50-59

Verified Purchase

September 01, 2026

Holy grail

Doesn't irritate or dry skin. Absorbs quickly and easily. A little goes a long way. Improves fine lines

4 people found this helpful

Profile picture of bwhitt.

bwhitt

from Alabama

Age Group: 70-79

Mature Skin

Verified Purchase

August 28, 2026

Gentle

I have seen much improvement in my skin without the drying and redness of other retinols. I will purchase again. I’m glad LovelySkin now carries skinbetter Science!

3 people found this helpful

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LovelySkin Customer

from Texas

Age Group: 70-79

Straight Hair

Mature Skin

Verified Purchase

August 18, 2026

Reduction of noticeable wrinkles

I started using this product about two months ago. I am 73 and for the first time noticed wrinkles is I've my upper lip. I started using this cream in conjunction with Replenix Anti-Aging Nightcream. I perceive a noticeable improvement in the softness, plumpness of my skin and reduced appearance of wrinkles. I use this product first then lightly pat on the replenix each night. Love it.

5 people found this helpful

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LovelySkin Customer

from Colorado

Age Group: 80+

Wavy Hair

Mature Skin

Verified Purchase

July 25, 2026

So far so good

I have 3 of the new skinbetter science products LovelySkin is now offering. This one having Rena A & so far no irritation to my mature, 81 year old skin..plus I am a redhead with very sensitive skin. Am happy to be addition these serums to my skin care.

4 people found this helpful

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BethD

from New Mexico

Age Group: 70-79

Straight, Color treated hair

Mature Skin

Verified Purchase

June 28, 2026

Nice product

I like the feel of this product: it absorbs quickly and doesn't burn or sting. I haven't tried it on my neck; all the other retinoids I've used make my neck very red and itchy so I'm a little reluctant to use this on more sensitive skin. I'll give it a try eventually.

4 people found this helpful

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LovelySkin Customer

from Florida

Age Group: 80+

Mature Skin

Verified Purchase

June 06, 2026

AlphaRet overnight cream

So far not seeing any fantastic results; although I'm not experiencing irritation as I have experienced with other retinoids. I also have the Ampra volumizing serum which I like very much as is not heavy o sticky. I've been using after the AlphaRet at night, which I'm hoping is the correct order in which to use.

5 people found this helpful

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LovelySkin Customer

Verified Purchase

June 03, 2026

Must have

I started with the Alpharet Clearing Serum, because I’m prone to milia. It did an excellent job keeping my skin clear, but I felt pushing 40 I needed to switch to this. I have a terrible allergy to retinol-this NEVER gave me any reaction. Skin is clear and beautiful. Price point is high but it lasts a long time.

4 people found this helpful

Profile picture of acharkins.

acharkins

Verified Purchase

June 01, 2026

Love this!

Have been using for a couple years, love how it makes my skin look! So glad it’s available to purchase here.

3 people found this helpful

Profile picture of Missy661.

Missy661

from California

Verified Purchase

May 17, 2026

AlphaRet Overnight Cream

I know it’s pricey but if you could get one product.. this is the one!!

4 people found this helpful

Profile picture of spope.

spope

from California

Age Group: 60-69

Mature Skin

Verified Purchase

May 03, 2026

I love this product!

I am switching to "cleaner" products and I find this product just as effective as the "industry standard". I am starting with this formula and will switch to their intensive strength when I have finished this bottle. Or.....I may titrate and purchase the stronger version sooner. I am looking forward to trying more SkinBetter Science products.

4 people found this helpful

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