skinbetter science AlphaRet Overnight Cream

4.8 View 13 reviews

$145.00

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Highlights

Retinoid results without the irritation
Plumps and firms skin with peptides

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$145.00

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Product Overview

skinbetter science AlphaRet Overnight Cream uses a retinoid and AHA blend to visibly rejuvenate skin.

Powered by patented AlphaRet technology, this award-winning formula combines a retinoid with lactic acid to improve the look of lines, wrinkles, uneven tone and texture—with minimal irritation. A blend of peptides, ceramides and squalane helps support firmness while delivering lasting hydration for a smoother, more radiant complexion.

Key Features:

AlphaRet technology renews skin with less irritation than traditional retinoids
Ceramides, squalane and hydrating ingredients provide lasting moisture
Dermatologist tested and formulated without parabens, fragrances or dyes

Highlights

Retinoid results without the irritation
Plumps and firms skin with peptides
Promotes a healthy microbiome

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Featured In

Customer Reviews (13)

Overall Rating

4.8

Based on 13 reviews

Review Summary

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13 Reviews

MargaretMarie

from Michigan

Age Group: 30-39

Combination Skin

Verified Purchase

September 16, 2026

Great on sensitive skin

Great if your skin is sensitive to standard retinols. I can use every night and I’m never irritated!

0 people found this helpful

LovelySkin Customer

from California

Age Group: 30-39

Wavy Hair

Combination Skin

Verified Purchase

September 15, 2026

10/10 overnight cream

I love the Alpharet overnight cream. It gentle on my face yet works to reduce my fine lines and dark spots. Must wear sunscreen!

0 people found this helpful

LovelySkin Customer

from Pennsylvania

Age Group: 50-59

Verified Purchase

September 01, 2026

Holy grail

Doesn't irritate or dry skin. Absorbs quickly and easily. A little goes a long way. Improves fine lines

3 people found this helpful

bwhitt

from Alabama

Age Group: 70-79

Mature Skin

Verified Purchase

August 28, 2026

Gentle

I have seen much improvement in my skin without the drying and redness of other retinols. I will purchase again. I’m glad LovelySkin now carries skinbetter Science!

2 people found this helpful

LovelySkin Customer

from Texas

Age Group: 70-79

Straight Hair

Mature Skin

Verified Purchase

August 18, 2026

Reduction of noticeable wrinkles

I started using this product about two months ago. I am 73 and for the first time noticed wrinkles is I've my upper lip. I started using this cream in conjunction with Replenix Anti-Aging Nightcream. I perceive a noticeable improvement in the softness, plumpness of my skin and reduced appearance of wrinkles. I use this product first then lightly pat on the replenix each night. Love it.

3 people found this helpful

LovelySkin Customer

from Colorado

Age Group: 80+

Wavy Hair

Mature Skin

Verified Purchase

July 25, 2026

So far so good

I have 3 of the new skinbetter science products LovelySkin is now offering. This one having Rena A & so far no irritation to my mature, 81 year old skin..plus I am a redhead with very sensitive skin. Am happy to be addition these serums to my skin care.

4 people found this helpful

BethD

from New Mexico

Age Group: 70-79

Straight, Color treated hair

Mature Skin

Verified Purchase

June 28, 2026

Nice product

I like the feel of this product: it absorbs quickly and doesn't burn or sting. I haven't tried it on my neck; all the other retinoids I've used make my neck very red and itchy so I'm a little reluctant to use this on more sensitive skin. I'll give it a try eventually.

4 people found this helpful

LovelySkin Customer

from Florida

Age Group: 80+

Mature Skin

Verified Purchase

June 06, 2026

AlphaRet overnight cream

So far not seeing any fantastic results; although I'm not experiencing irritation as I have experienced with other retinoids. I also have the Ampra volumizing serum which I like very much as is not heavy o sticky. I've been using after the AlphaRet at night, which I'm hoping is the correct order in which to use.

5 people found this helpful

LovelySkin Customer

Verified Purchase

June 03, 2026

Must have

I started with the Alpharet Clearing Serum, because I’m prone to milia. It did an excellent job keeping my skin clear, but I felt pushing 40 I needed to switch to this. I have a terrible allergy to retinol-this NEVER gave me any reaction. Skin is clear and beautiful. Price point is high but it lasts a long time.

4 people found this helpful

acharkins

Verified Purchase

June 01, 2026

Love this!

Have been using for a couple years, love how it makes my skin look! So glad it’s available to purchase here.

3 people found this helpful

Missy661

from California

Verified Purchase

May 17, 2026

AlphaRet Overnight Cream

I know it’s pricey but if you could get one product.. this is the one!!

4 people found this helpful

spope

from California

Age Group: 60-69

Mature Skin

Verified Purchase

May 03, 2026

I love this product!

I am switching to "cleaner" products and I find this product just as effective as the "industry standard". I am starting with this formula and will switch to their intensive strength when I have finished this bottle. Or.....I may titrate and purchase the stronger version sooner. I am looking forward to trying more SkinBetter Science products.

4 people found this helpful

Kendog

from Massachusetts

Verified Purchase

April 30, 2026

Clears my skin

I do like this retinol. My skin is sensitive but this never Burns or irritates my skin. The only thing I don’t like is that Skinbetter doesn’t reveal the strength of retinol in this product.

13 people found this helpful

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skinbetter science AlphaRet Overnight Cream

Product Overview

skinbetter science AlphaRet Overnight Cream uses a retinoid and AHA blend to visibly rejuvenate skin.

Highlights

Ingredients

Directions

Shipping & Returns

Questions & Answers

Product Specifications

Special Offers

Featured In

Customer Reviews (13)

Overall Rating

Review Summary

Write a Review

Great on sensitive skin

10/10 overnight cream

Holy grail

Gentle

Reduction of noticeable wrinkles

So far so good

Nice product

AlphaRet overnight cream

Must have

Love this!

AlphaRet Overnight Cream

I love this product!

Clears my skin

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