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SkinCeuticals A.G.E. Interrupter Advanced Corrective Cream

1.7 fl oz
| HSA/FSA Eligible LMN Required
$185.00

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Highlights
  • Concentrated anti-aging treatment
  • Improves sallow tone and deep wrinkles

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Product Overview

SkinCeuticals A.G.E. Interrupter Advanced Corrective Cream helps reverse visible aging impacted by collagen decline and glycation.

Advanced glycation end products (A.G.E.s) are by-products of a natural, multi-phase biological process in which sugars bind to collagen, causing it to degrade in integrity and become brittle. Additionally, environmental and lifestyle factors like pollution, smoking and diet can cause even more oxidative stress and accelerate the formation of A.G.E.s, contributing to skin laxity, wrinkles and loss of firmness. This advanced, corrective treatment cream offers 24 hours of hydration in a rich, satin texture to help improve accelerated to advanced signs of aging by addressing multiple stages of the glycation process to improve visible wrinkles, restore firmness and enhance radiance.

Clinical results of a 12-week study of 77 females with Fitzpatrick types I-VI, ages 35-75 found the following improvements:

  • 14% global fine lines
  • 11.5% forehead wrinkles
  • 11.2% nasolabial folds
  • 7.9% marionette wrinkles
  • 7.3% glabellar wrinkles
  • 7% crow's feet

Key Features:

  • 18% concentrated proxylane at 12.5% activity optimizes collagen matrix integrity to repair existing damage like wrinkles and laxity
  • 4.25% wild fruit flavonoid blend of blueberry and pomegranate extracts reverses the early stages of glycation
  • 0.1% glycyrrhetinic acid defends against the reoccurrence of new A.G.Es
  • 3% HEPES activates natural enzymes in skin to promote cell turnover and support hydration
  • 1% niacinamide helps support the skin's moisture barrier
  • Supports hyaluronic acid synthesis in the skin and reduces the inflammatory response caused by A.G.E. formation
  • Visibly smooths fine lines and five wrinkle types, including forehead wrinkles, nasolabial folds, marionette wrinkles, glabellar wrinkles, and crow's feet

NOTE: Due to the high concentration of naturally derived flavonoids, this cream's color may vary but results will remain constant.

Highlights

  • Concentrated anti-aging treatment
  • Improves sallow tone and deep wrinkles
  • Ideal for accelerated skin aging

Ingredients

Directions

Shipping & Returns

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Return Policy: This product is non-returnable

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Special Shipping Requirements: ORM-D Class
ORM-D classified products such as aerosol sprays, nail polish, perfume and products with high alcohol content may only be shipped using a ground method within the Continental US.

Availability: In stock & ready to ship! . Ships within the U.S. only.

Questions & Answers (2)

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Product Specifications

About the Brand

Customer Reviews (221)

Overall Rating

4.4
Based on 221 reviews

Review Summary

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221 Reviews

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LovelySkin Customer

from West Virginia

Age Group: 70-79

Straight Hair

Mature Skin

Verified Purchase

July 22, 2026

A.G.E. Interrupter

I have been using this product as a day time moisturizer for about 6 months. I like how it feels on the skin & it does not pill under makeup

0 people found this helpful

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LovelySkin Customer

from Illinois

Age Group: 50-59

Mature Skin

Verified Purchase

July 19, 2026

Nothing else like it

This is the best product I have found. Mature skin on the drier side (56 years old with melanoma). I keep trying to find a cheaper alternative and nothing else comes close to the hydration and plumpness this brings to my skin. Keep coming back to this.

0 people found this helpful

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Bano

from California

Verified Purchase

July 10, 2026

great quality

A little goes a long way, so the jar lasts longer than expected. While it's definitely an investment, the quality of the ingredients and the visible improvements make it worth the price. If you're looking for a premium corrective moisturizer that helps address multiple signs of aging while leaving your skin soft, hydrated, and refreshed, I highly recommend SkinCeuticals A.G.E. Interrupter Advanced Corrective Cream.

1 person found this helpful

Profile picture of AIP.

AIP

from Florida

Age Group: 60-69

Wavy hair, Damage & split ends

Combination Skin

Verified Purchase

June 24, 2026

SkinCeuticals A.G.E. Interrupter Advanced Corrective Cream

I have been using SkinCeuticals A.G.E. Interrupter Advanced Corrective Cream on and off, but since last year It has become my go to cream for night time moisturizer and also daytime routine for dry areas on my face. Age 66 years. Normal to dry skin.

1 person found this helpful

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LovelySkin Customer

Verified Purchase

June 19, 2026

Great Product!

The A.G.E Interrupter Advanced is amazing. I have been using it for several years. It does work on reducing fine line and softens deep wrinkles. My skin texture has improved. It contains antioxidant protection, which enhances my skin's appearance as well! I highly recommend it.

1 person found this helpful

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LovelySkin Customer

Verified Purchase

June 07, 2026

Didn't do much

I have sensitive, redness prone, normal-to-dry skin with acne rosacea. AGE Cream didn't work as well as the Triple Lipid Restore. It didn't seem to do much.

2 people found this helpful

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LovelySkin Customer

from Arizona

Age Group: 70-79

Verified Purchase

May 31, 2026

A.G.E interrupter

I just added this to my Skin Ceutical regime. I use it at night and am very happy with the results I’m seeing. It is not heavy or greasy but gives me plenty of moisture.

0 people found this helpful

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Lucy2

from California

Dry Skin

Verified Purchase

May 23, 2026

Great Moisturizer

I've just finished my 1st jar of this product and I love it! It's hydrating for my dry skin and keeps face moisturized all day. Am looking forward to continuing with my 2nd jar to see progress.

1 person found this helpful

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LovelySkin Customer

from Iowa

Age Group: 60-69

Curly Hair

Normal Skin

Verified Purchase

May 06, 2026

SkinCeuticals A.G.E. Advanced Corrective Cream

I used this cream for months on my face and neck and seen no results. So I thought to myself why not try it on my chest WOWZA! I SEEN RESULTS RIGHT AWAY!!!! IM 63 AND MY CHEST IS SMOOTH AND GLOWING WITH NO MORE CREAPY SKIN! I highly recommend to give this a try!!! Thank you, Lovely Skin

1 person found this helpful

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LovelySkin Customer

from Massachusetts

Age Group: 60-69

Wavy, Color treated hair

Mature Skin

Verified Purchase

April 09, 2026

Maybe good for you

I’d been anxious to try this, based on my brand love and great reviews. Ordered, but had to return due to the OVERWHELMING level of fragrance. I was shocked, actually, that the scent was so strong given many Skinceuticals products are not so scented. Couldn’t tolerate. LovelySkin has the best customer service. I only lost the cost of return shipping, but was spared skin outrage due to fragrance factor.

5 people found this helpful

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LovelySkin Customer

from Florida

Age Group: 50-59

Normal Skin

Verified Purchase

April 07, 2026

AGE interrupter advanced is amazing

AGE interrupter Advanced is one of my favorite products! I love the texture and I love the way it makes your skin feel. I wear it to go to sleep and in the morning, my face feels refreshed!

0 people found this helpful

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LovelySkin Customer

from Kentucky

Age Group: 70-79

Wavy Hair

Combination Skin

Verified Purchase

April 04, 2026

Love, love, love

This product does everything it is supposed to do. I use it after CE Ferulic nightly and my skin looks really healthy!!! I get compliments from everyone, especially from my dermatologist during my yearly visit!

3 people found this helpful

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Ar

from North Carolina

Verified Purchase

April 02, 2026

positivity

Always enjoy having this cream and using it daily. My skin is in good shape because of using it daily

3 people found this helpful

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Boca

Verified Purchase

March 30, 2026

This product works

I have used this product in the past and went back to it. I really notice the change in my skin and how firm it feels. You still feel the moisture in the morning. I mainly use at night. I will continue to use even though it is expensive, a little goes a long way.

4 people found this helpful

Profile picture of Desi.

Desi

Verified Purchase

March 11, 2026

It ok

I loved the old formula better. It’s not terrible, but takes quite a bit to rub into your skin. And forget about layering with a serum before applying this to my face it was super sticky. Wish they won’t change something that works.

2 people found this helpful

Profile picture of Flowers.

Flowers

from Florida

Verified Purchase

February 28, 2026

Works

My skin looks much better I will reorder

0 people found this helpful

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Edie

from Oklahoma

Age Group: 70-79

Mature Skin

Verified Purchase

February 21, 2026

Flakes and pills

I tried this for first time because I had used Skinceuticals products before. But this product does not absorb well and flakes on my skin. I should have bought Skinceuticals Triple Lipid cream as I have in the past.

2 people found this helpful

Profile picture of Hepa.

Hepa

from North Carolina

Age Group: 50-59

Straight Hair

Mature Skin

Verified Purchase

February 10, 2026

My Go to Face Moisturizer

I can't say enough about this moisturizer. I have given up using anything else on my mature skin. It changed the texture of my facial skin so it is much smoother. It is light and easy to wear, especially good in the summer months. The one downside is the price but I'm happy to pay it - I have dry mature skin, and I hate the thick feeling of a lot of the other facial moisturizers. So for me it is a combination of the light feel (you don't have to use much), and that I watched the texture of my face soften and become smoother.

4 people found this helpful

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LovelySkin Customer

from California

Age Group: 70-79

Straight, Color treated hair

Mature Skin

Verified Purchase

January 29, 2026

Very sticky even when using a very small amount

I tried all of the techniques for making this less sticky and still disliked the texture. I finally gave up and just used it on my chest. Doesn’t seem to be doing anything. My face actually stuck to my pillow a night, even when using a teeny amount and patting it in. I love other SkinCeuticals products but this was not one of them.

3 people found this helpful

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LovelySkin Customer

Verified Purchase

January 09, 2026

Love the cream

This is a wonderfully rich cream to use at night. I am a senior and the cream gives me the moisture that holds through out the night. SkinCeutical skin care products are my favorite although they are pricey. I usually wait for a discount before I replenish. If you can afford it, it is the best.

2 people found this helpful

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