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SkinCeuticals A.G.E. Interrupter Advanced Corrective Cream

1.7 fl oz
| HSA|FSA Eligible LMN Required
$185.00
Highlights
  • Concentrated anti-aging treatment
  • Improves sallow tone and deep wrinkles
  • Ideal for accelerated skin aging
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Product Overview

SkinCeuticals A.G.E. Interrupter Advanced Corrective Cream helps reverse visible aging impacted by collagen decline and glycation.

Advanced glycation end products (A.G.E.s) are by-products of a natural, multi-phase biological process in which sugars bind to collagen, causing it to degrade in integrity and become brittle. Additionally, environmental and lifestyle factors like pollution, smoking and diet can cause even more oxidative stress and accelerate the formation of A.G.E.s, contributing to skin laxity, wrinkles and loss of firmness. This advanced, corrective treatment cream offers 24 hours of hydration in a rich, satin texture to help improve accelerated to advanced signs of aging by addressing multiple stages of the glycation process to improve visible wrinkles, restore firmness and enhance radiance.

Clinical results of a 12-week study of 77 females with Fitzpatrick types I-VI, ages 35-75 found the following improvements:

  • 14% global fine lines
  • 11.5% forehead wrinkles
  • 11.2% nasolabial folds
  • 7.9% marionette wrinkles
  • 7.3% glabellar wrinkles
  • 7% crow's feet

Key Features:

  • 18% concentrated proxylane at 12.5% activity optimizes collagen matrix integrity to repair existing damage like wrinkles and laxity
  • 4.25% wild fruit flavonoid blend of blueberry and pomegranate extracts reverses the early stages of glycation
  • 0.1% glycyrrhetinic acid defends against the reoccurrence of new A.G.Es
  • 3% HEPES activates natural enzymes in skin to promote cell turnover and support hydration
  • 1% niacinamide helps support the skin's moisture barrier
  • Supports hyaluronic acid synthesis in the skin and reduces the inflammatory response caused by A.G.E. formation
  • Visibly smooths fine lines and five wrinkle types, including forehead wrinkles, nasolabial folds, marionette wrinkles, glabellar wrinkles, and crow's feet

NOTE: Due to the high concentration of naturally derived flavonoids, this cream's color may vary but results will remain constant.

Highlights

  • Concentrated anti-aging treatment
  • Improves sallow tone and deep wrinkles
  • Ideal for accelerated skin aging

Ingredients

Directions

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ORM-D classified products such as aerosol sprays, nail polish, perfume and products with high alcohol content may only be shipped using a ground method within the Continental US.

Availability: In stock & ready to ship! . Ships within the U.S. only.

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Product Specifications

About the Brand

Customer Reviews (194)

Overall Rating

4.4
Based on 194 reviews

Review Summary

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194 Reviews

Profile picture of JaniceMary.

JaniceMary

from Colorado

Age Group: 70-79

Straight hair, Damage & split ends

Dry Skin

Verified Purchase

November 24, 2025

Best Moisturizer for Dry Older Skin

I love, love this moisturizer. I am 78 with dry skin and living in Colorado makes it even worse. Swear by this.

0 people found this helpful

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ALHB

from Minnesota

Age Group: 50-59

Combination Skin

Verified Purchase

November 12, 2025

Initial results are great

I've been using this for a couple of years. Initially I saw terrific results in the fine lines and elasticity of my skin. The results have leveled off though. It is moisturizing and has a lovely smooth texture. I do wonder if there is benefit to switching to Triple Lipid Restore for a few months and then coming back to AGE Interrupter?? Perhaps alternating the two would enhance the benefits of each?? Just a thought....

0 people found this helpful

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Rommie

from Pennsylvania

Age Group: 60-69

Curly, Dry Hair

Normal Skin

Verified Purchase

November 11, 2025

Skincueticals A.G.E. Interrupter

I love skincueticals but not this product. It doesn't absorb into my skin at all. It leaves a mess that I have to wipe off.

1 person found this helpful

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Maggie2

from North Carolina

Age Group: 70-79

Straight, Color treated hair

Mature Skin

Verified Purchase

November 09, 2025

Great cream.

I had been using and loved the triple lipid restore 2-4-2 cream but decided to give the age interrupter a try. I love it too!!! It feels so good on my skin and absorbs really well. I wish I could say it turned back the clock on my 74 year old skin, but years of no sunscreen have taken a toll. But I still think it helps smooth out the fine wrinkles and I am highly recommending it to my 41 year old daughter.

0 people found this helpful

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LovelySkin Customer

from South Carolina

Age Group: 70-79

Straight Hair

Normal Skin

Verified Purchase

November 04, 2025

Love this for my aging skin.

I have been looking for something to use at night with my moisturizer that did more than moisturize. Often I don't need a moisturizer, but want something to support my skin. Have been using Skinceuticals for over 20 years and this has become one of my favorite products.

0 people found this helpful

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BethD

from Nevada

Age Group: 70-79

Wavy, Color treated hair

Mature Skin

Verified Purchase

November 01, 2025

Rich and luxe

I use this as a night cream to help with dryness from upping my retinol dose. It's a very rich cream and a little goes a long way. I haven't been using it very long (2 weeks) but it feels nice on my skin and not greasy at all.

0 people found this helpful

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RandiR

from Pennsylvania

Age Group: 60-69

Normal Skin

Verified Purchase

October 26, 2025

My bed time favorite!

If you’re looking for a restful night sleep then look no further. My evening routine includes Skin Ceuticals A.G.E. Interrupter Advance Corrective Cream followed by my retinol every night and my skin feels so nourished. Been using this product for years and for years to come! Thank you Skin Ceuticals

0 people found this helpful

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LovelySkin Customer

Verified Purchase

October 24, 2025

Still my favorite

I've used this eye cream for almost 10 years, and it's still my favorite.

0 people found this helpful

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jtcalicoast

from California

Verified Purchase

October 04, 2025

Excellent....Just the Best!!

I use this as a night cream ... I don't think I've had a better product on my skin..... I noticed a difference in week 2.... I was surprised w/that.....I am an older woman so this is a huge endorsement .

2 people found this helpful

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LovelySkin Customer

from Minnesota

Age Group: 40-49

Curly Hair

Mature Skin

Verified Purchase

October 01, 2025

Silky smooth

I have used so many different creams over the years and this one is by far my favorite. There is intense hydration without feeling greasy. It leave my skin feeling silky smooth, protected, and moisturized. This is one of my favorite products and I will continue to purchase this.

1 person found this helpful

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LovelySkin Customer

from Georgia

Age Group: 60-69

Mature Skin

Verified Purchase

September 26, 2025

Not crazy about the scent

I like what the cream does to my skin, but after I use it, the scent seems to follow me around.

0 people found this helpful

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LovelySkin Customer

from Minnesota

Age Group: 70-79

, Dry Hair

Mature Skin

Verified Purchase

September 26, 2025

Skin Ceuticals A.G.E. Interrupter Treatment

This thick non greasy concentrated treatment is wonderful! The product does really repair my skin. My skin is much more soft, firmer, plumper, hydrated. The lines and wrinkles are much less noticeable. I have been using this professional quality product for many years and will continue to purchase this great healing treatment. I highly recommend this corrective treatment.

0 people found this helpful

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LovelySkin Customer

Verified Purchase

September 25, 2025

I love the A.G.E. Interrupter products

While I always use Skin Ceutical products, i decide every now and again to try others than A.G.E. Interrupter, for eyes and face. I do like Triple Lipids, but love the way A.G.E. sinks in to my skin.

0 people found this helpful

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LovelySkin Customer

Verified Purchase

September 21, 2025

Love it!

Creamy with a fresh scent.

0 people found this helpful

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LovelySkin Customer

from Vermont

Age Group: 50-59

Verified Purchase

September 19, 2025

Smooth and Tightening

Love how this glides on and has a matte finish.

1 person found this helpful

Profile picture of Chrissie25.

Chrissie25

Verified Purchase

September 17, 2025

AGE Advanced Cream

So happy with skinceuticals they work so well and make my skin feel and look great. Great products for mature skin.

0 people found this helpful

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LovelySkin Customer

from Florida

Verified Purchase

September 13, 2025

Go To Anti-aging moisturizer

This moisturizer is the real deal. I noticed improvement the morning after the first use. I like texture of the cream and a little goes a long way. I will purchase this product again…and again!

1 person found this helpful

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LovelySkin Customer

from Tennessee

Verified Purchase

September 08, 2025

Great Cream for aging skin

Bought this on the recommendation of my facialist. The product is nice and does not appear to cause "balling" with other products

0 people found this helpful

Profile picture of HomeGirlToo.

HomeGirlToo

Age Group: 70-79

Mature Skin

Verified Purchase

September 04, 2025

Not effective

Heavy, sticky, non-absorbing, scented and entirely ineffective. Seems to leave a 'coating' on the skin. It has turned into a spendy hand/foot cream. Do not recommend and will not repurchase.

1 person found this helpful

Profile picture of Kristine595.

Kristine595

from Texas

Age Group: 50-59

Wavy Hair

Mature Skin

Verified Purchase

August 29, 2025

Excellent for advanced aging concerns

This is my second jar of A.G.E. interrupter advanced treatment that I purchased, and I believe it lives up to most of its claims. I would classify this as a treatment rather than a moisturizer because, IMHO, its consistency is dryer than a cream, doesn't seem to absorb very well and isn't very moisturizing. It does, however, address the signs of aging (laxity, wrinkles, skin tone, etc.) that occur in advanced aging. I have incorporated this into my mainly Skinceuticals skincare regime and find it works well with other products as well. I was previously using the Triple Lipid moisturizer and find that this works better for firming, wrinkles and plumping to address sagging skin while the Triple Lipid moisturizer worked better at moisturizing and radiance/glow.

5 people found this helpful

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