SkinCeuticals Anti-Wrinkle Serum Duo with C E Ferulic & P-TIOX

4.7 View 25 reviews

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$335.00

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Highlights

Strengthens the skin barrier
Suitable for all skin types and tones

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Product Overview

SkinCeuticals Anti-Wrinkle Serum Duo encourages a more youthful look.

This kit combines the clinically proven antioxidant support of C E Ferulic Antioxidant Serum with the line-smoothing power of P-TIOX. Featuring gentle chemical exfoliators, 15% pure vitamin C, 1% pure vitamin E and 0.5% ferulic acid, it provides visible anti-aging benefits while delivering your most radiant skin yet.

Set Includes:

C E Ferulic Antioxidant Serum (1.0 fl oz)
P-TIOX Wrinkle Modulating Peptide Serum (1.0 fl oz)

Clinical Results:

P-TIOX reveals glass skin radiance in as little as 1 week
-36% wrinkles and +37% firmness after four months of C E Ferulic

Key Features:

Reduces the appearance of nine types of expression lines
Hydrates, calms and strengthens the moisture barrier
Minimizes the look of discoloration

Highlights

Strengthens the skin barrier
Suitable for all skin types and tones
Provides anti-aging benefits

Ingredients

Directions

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Product Specifications

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About the Brand

Customer Reviews (25)

Overall Rating

4.7

Based on 25 reviews

Review Summary

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25 Reviews

Pony

Verified Purchase

March 18, 2026

I like it

I received a sample of the ptiox and had already been in using the vit c serum. Both work well for me.

0 people found this helpful

Eye

from Massachusetts

Age Group: 60-69

Wavy, Color treated hair

Combination Skin

Verified Purchase

March 08, 2026

Beautiful pairing !

I love the combination of the two in addition to a hydrating night cream and an SPF face cream in the morning. I sometimes layer the serums using HA in addition to the P-Tiox. The only negative for me is the cost ..I wish they could figure out a way to make this more affordable!

0 people found this helpful

LovelySkin Customer

from West Virginia

Age Group: 60-69

Straight, Color treated hair

Normal Skin

Verified Purchase

March 02, 2026

Great Products

I love this combo; I use twice daily. I am 67 ears old and receive compliments on my skin. I do not want to be without these products. I ensure when I am running low my order goes in for replenishment I do wish the price was a bit lower.

0 people found this helpful

Shg123

from Mississippi

Age Group: 50-59

Wavy Hair

Combination Skin

Verified Purchase

February 19, 2026

Dynamic duo

I love both of these products!!! My favorite of all time!!!!!

0 people found this helpful

4girlmom

from Colorado

Age Group: 50-59

Combination Skin

Verified Purchase

February 19, 2026

Great price!

I have loved the CE Ferulic for a while and never let this product run out. I use it everyday to protect my skin from the harsh Colorado climate. I recently tried the p-tiox and decided to buy the full size. I have been using it every night for about a week. I think it will become a staple in my daily routine, just like the vit. c.

1 person found this helpful

LovelySkin Customer

from North Carolina

Age Group: 70-79

Mature Skin

Verified Purchase

February 15, 2026

Serum Duo

Have used this duo for a few weeks and I’m very happy with the results. The fine lines are not gone but have softened tremendously. At 78 every little bit helps!

2 people found this helpful

LovelySkin Customer

from Wisconsin

Age Group: 50-59

Wavy Hair

Normal Skin

Verified Purchase

January 08, 2026

Works great!

Love these two products! Just started using them together a week ago and I've noticed a slight improvement in the depth and appearance of my wrinkles. Skin texture feels better along with the brightness of my skin. I think with consistent use, this will improve my skin appearance.

0 people found this helpful

Mof2

Age Group: 80+

Mature Skin

Verified Purchase

January 06, 2026

CE Ferulic and Ptiox

I enjoy using the CE Ferulic. It keeps my skin looking young and healthy. I am well into my second bottle of Ptiox and have not seen a big difference in the lines in my face. Hopefully, it will keep them from getting worse.

1 person found this helpful

Kayter

from Oklahoma

Age Group: 30-39

Straight Hair

Combination Skin

Verified Purchase

January 04, 2026

Mehh

I recently tried both of these skin care serums, and I must say, I was really disappointed with the P-Tiox. Despite the promising claims on the packaging, I didn’t see any noticeable difference in my skins appearance. The serum absorbed somewhat quick but left a sticky residue that made it uncomfortable to wear throughout the day. Additionally, I experienced some irritation after just a few uses, which was unexpected. Overall, I wouldn’t recommend the P-Tiox, as it didn't live up to its hype and ended up being a waste of money for me. As for the C E Ferulic I have no complaints and will keep it in my skincare routine

2 people found this helpful

LuLu12

from California

Age Group: 60-69

Straight Hair

Dry Skin

Verified Purchase

December 25, 2025

Love CE FERULIC - undecided on PTox serum

Love ce ferulic and decided to add ptox to my routine. Not sure how effective the ptox is but I will give it some time to see if it’s worth refilling.

2 people found this helpful

FancySusie

from Texas

Age Group: 70-79

Straight Hair

Mature Skin

Verified Purchase

December 22, 2025

My Go To

I have used CE Ferulic since it came out. We carried it and lots of other Skinceutical products in my husband’s plastic surgery practice. I added P-Tox when it was introduced and use them both every day. I am 73 years old and my skin looks soooo much better than others. Thank you Skinceuticals. You are the good standard.

1 person found this helpful

Flowers

from New York

Verified Purchase

December 13, 2025

Flawless

My skin looks smoother and healthier I have gotten many compliments

0 people found this helpful

Josephine

Verified Purchase

December 09, 2025

Serum duo -Ferulic and ptiox

Recently purchased this product. Use it daily - skin feels much softer and well hydrated. Wrinkle lines are less pronounced. Highly recommend products. Remember - use daily for best results

2 people found this helpful

mimi77

from Texas

Age Group: 70-79

Wavy Hair

Dry Skin

Verified Purchase

October 25, 2025

great combo for a product junkie

I find good result from pairing SkinCeuticals C E Ferulic with PTIOX every morning. I am 78, recently went to my 60th high school reunion, was informally voted "best skin". To be fair, I used Tazarac for 30 years until my very oily skin became drier and I live in a hot, humid climate. Of course, sunscreen always and retinol at night, too. I always wait for a sale but if I could purchase only 1 item I think the PTIOX would be my first choice for now.

6 people found this helpful

LovelySkin Customer

from Puerto Rico

Age Group: 50-59

Curly, Dry Hair

Mature Skin

Verified Purchase

October 13, 2025

Excellent !!

-excelente combination. I use it every day and have recommended it to several friends. They also bought it at LovelySkin

1 person found this helpful

LovelySkin Customer

from Louisiana

Age Group: 70-79

Normal Skin

Verified Purchase

August 12, 2025

Couldn't do without!

I am a loyal user of CE Ferulic - LOVE it and know my skin would not look the same without it. I am a new user of p-Tiox. I have not finished a bottle of it yet so I'm not certain of results - therefore 4 stars for the combo rather than 5 stars. I feel certain that the long-term results will not disappoint.

3 people found this helpful

GemLizzy

Verified Purchase

May 26, 2025

The BEST Duo

I wanted to wait a year before writing a review on Skinceutical products. I wanted to see if I would noticed any changes/improvements in my skin as some products may take a few months before you can see results. I actually began seeing results after a month! I LOVE Skinceuticals C E Ferulic. I use it in my morning routine before applying my sunscreen and P-TIOX AND Triple Lipid Restore for my nighttime routine. I have replaced ALL my skin care products with Skinceuticals and am NEVER going back. LOVE LOVE LOVE Skinceutical skincare products!

11 people found this helpful

Tary

Verified Purchase

May 23, 2025

O love this stuff

My Derm recommended, I’m 73plus and I think I’m seeing softer wrinkles and skin feels soft

5 people found this helpful

LovelySkin Customer

Verified Purchase

May 15, 2025

Best Duo

Love the results I am seeing from this duo! I feel glowy and plumped up every morning!

4 people found this helpful

LovelySkin Customer

Verified Purchase

April 26, 2025

Quality Serums for My Skin

I have been using CE Ferulic for years and my skin loves it; the P-Tiox is a fabulous addition. I noticed a remarkable difference in the radiance of my skin from the first time I started using it. Some products you have to use for awhile before they seem to work. In any case, I get compliments on my skin all the time, and I say, "Skinceuticals products!"

8 people found this helpful

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SkinCeuticals Anti-Wrinkle Serum Duo with C E Ferulic & P-TIOX

Product Overview

SkinCeuticals Anti-Wrinkle Serum Duo encourages a more youthful look.

Highlights

Ingredients

Directions

Shipping & Returns

Questions & Answers

Product Specifications

Special Offers

About the Brand

Customer Reviews (25)

Overall Rating

Review Summary

Write a Review

I like it

Beautiful pairing !

Great Products

Dynamic duo

Great price!

Serum Duo

Works great!

CE Ferulic and Ptiox

Mehh

Love CE FERULIC - undecided on PTox serum

My Go To

Flawless

Serum duo -Ferulic and ptiox

great combo for a product junkie

Excellent !!

Couldn't do without!

The BEST Duo

O love this stuff

Best Duo

Quality Serums for My Skin

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