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SkinCeuticals Triple Lipid Restore 2:4:2 Anti-Aging Cream

1.6 fl oz
| HSA/FSA Eligible LMN Required
$155.00
Highlights
  • Smooths the appearance of fine lines
  • Replenishes nourishing lipids
  • Provides 24 hour hydration

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Product Overview

SkinCeuticals Triple Lipid Restore 2:4:2 refills cellular lipids and nourishes skin. 

SkinCeuticals Triple Lipid Restore 2:4:2 is an anti-aging corrective treatment formulated with essential lipids at a patented percentage of 2% pure ceramides, 4% natural cholesterol and 2% fatty acids. This unique ratio helps restore the skin's moisture barrier, support natural repair processes and correct signs of aging. The result is an improvement in elasticity, moisture levels and radiance, leaving your skin supple, healthy and radiant.

In an eight-week study, SkinCeuticals Triple Lipid Restore users experienced significant improvement in key visible signs of accelerated aging:

  • 66% improvement in smoothness
  • 35% improvement in laxity
  • 20% improvement in evenness
  • 26% improvement in radiance
  • 44% improvement in pore appearance

In a lipidomic study, use of SkinCeuticals Triple Lipid Restore cream resulted in a:

  • 57% increase in ceramides
  • 50% increase in cholesterol
  • 12% increase in fatty acids in the form of triglycerides

Key Ingredients:

  • Essential Lipids: Featuring natural cholesterol, pure ceramides and fatty acids, they restore skin's youthful elasticity and hydration cycles
  • Vitamin E: Supports natural cell repair and reproduction, helping defend against environmental damage
  • Essential Oils: Packed with antioxidants to fight free-radical damage that is responsible for signs of aging

Key Features:

  • Improves the look of texture, skin tone evenness, and overall radiance
  • Shortens the adjustment period to retinoids up to 1 week while reducing dryness
  • Ideal for aging, normal, and dry skin types

Address roughness, dullness and restore facial fullness with SkinCeuticals Triple Lipid Restore 2:4:2.

Highlights

  • Smooths the appearance of fine lines
  • Replenishes nourishing lipids
  • Provides 24 hour hydration

Ingredients

Directions

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Return Policy: This product is non-returnable

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Special Shipping Requirements: ORM-D Class
ORM-D classified products such as aerosol sprays, nail polish, perfume and products with high alcohol content may only be shipped using a ground method within the Continental US.

Availability: In stock & ready to ship! . Ships within the U.S. only.

Questions & Answers (12)

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Product Specifications

About the Brand

Customer Reviews (2312)

Overall Rating

4.8
Based on 2312 reviews

Review Summary

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2312 Reviews

Profile picture of 1381new.

1381new

from Alabama

Verified Purchase

September 02, 2026

My skin loves it

Very nice product. So moisturizing I have cut back on daytime use due to the heatwave in my state. Apply in the evening and skin feels great in the morning.

3 people found this helpful

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AndreaV

from New York

Verified Purchase

August 27, 2026

My go to

Wonderful moisturizer for my 60-something skin.

4 people found this helpful

Profile picture of Mimi29.

Mimi29

from Virginia

Age Group: 70-79

Straight, Color treated hair

Mature Skin

Verified Purchase

August 24, 2026

Hydrating

Great moisturizing for aging skin

4 people found this helpful

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LovelySkin Customer

from North Carolina

Age Group: 50-59

Mature Skin

Verified Purchase

August 19, 2026

Perfect

I am a new user of Treninoin cream and needed a super thick moisturizer that helped as my skin sheds. This is doing the trick. My peeling has calmed down, subtle scent and feels like a babies skin. Love this!

4 people found this helpful

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DCarter

from Alabama

Age Group: 80+

Wavy Hair

Verified Purchase

August 18, 2026

The best moisturizer

Amazing barrier support, especially at night after using retinol. Amazing barrier repair and soothing effect

4 people found this helpful

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LovelySkin Customer

from Colorado

Verified Purchase

August 13, 2026

Exceptional moisturizer

So many creams just coat the skin, but the triple lipid actually feels like it soaks in and makes my skin feel soft, plumped and hydrated.

5 people found this helpful

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LovelySkin Customer

from Georgia

Age Group: 60-69

Straight, Color treated hair

Mature Skin

Verified Purchase

August 01, 2026

Best moisturizer ever

I've tried everything and this is probably the best moisturizer I've ever found. I just wish it would come in a tube or pump. It feels so luxurious, absorbs beautifully and skin looks amazing the next morning. More importantly skin still feels moisturized when I wake up. It's a hard overnight miracle worker.

7 people found this helpful

Profile picture of Rainydayz.

Rainydayz

from Oregon

Age Group: 50-59

Verified Purchase

July 27, 2026

All time Fav!

This is my number one all time favorite moisturizer. It provides amazing hydration and is no doubt worth the cost for youthful skin. I use it at nighttime only now, because there are so many great moisturizers to alternate from Skin Ceuticals Brand purchased from Lovely Skin who carries the best selection!

6 people found this helpful

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LovelySkin Customer

from Massachusetts

Age Group: 60-69

Mature Skin

Verified Purchase

July 23, 2026

SkinCeuticals

I switched back and I’m glad I did. My skin feels so good.

8 people found this helpful

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LovelySkin Customer

from Maryland

Age Group: 70-79

Mature Skin

Verified Purchase

July 20, 2026

Best moisturizer

I love this product. It keeps my face moisturized all day long. Although it’s expensive, a little goes a long way.

5 people found this helpful

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LovelySkin Customer

from Florida

Age Group: 60-69

Verified Purchase

July 18, 2026

Expected more

From the reviews and the price, I expected more from this moisturizer. It’s fine and right after I put it on my face, my face feels softer, however, that “moisture” doesn’t seem much different other than right away. It’s only been a couple of weeks, but unless all of a sudden there’s a drastic change in my skin, I won’t be purchasing this again. Very disappointing.

4 people found this helpful

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Karen7

from California

Age Group: 80+

Straight, Color treated hair

Mature Skin

Verified Purchase

July 17, 2026

Very Best SkinCeutical Moisturizer

I love my SkinCeutical Triple Liquid Restore moisturizer so much that I buy ahead so I never run out. I am 86 years old and I have been using SkinCeutical products especially my Triple Liquid Restore for years. I always hear how great my skin looks. Whenever I decide to try something new, I always come right back to Triple Liquid Restore Moisturizer. I also purchase all my skin care from Lovely Skin. Thank You So Much

6 people found this helpful

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LovelySkin Customer

from New York

Age Group: 60-69

Wavy, Color treated hair

Normal Skin

Verified Purchase

July 16, 2026

Love it

I have been using Triple Lipid for many months now and I have seen great results I use it as my final product on my fave I highly recommend this I am 63 years old and my skin looks and feels great

4 people found this helpful

Profile picture of Pinktiger.

Pinktiger

from Alabama

Age Group: 60-69

Verified Purchase

July 05, 2026

Wow!

This really does make my retinol using skin more supple and moisturized. Also improves my wrinkles and fine lines.

3 people found this helpful

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LovelySkin Customer

from Illinois

Verified Purchase

July 05, 2026

Love it

Works great!

3 people found this helpful

Profile picture of MFender.

MFender

from Georgia

Age Group: 40-49

Verified Purchase

July 02, 2026

Buy it!

This product has been so amazing for my skin. I could use just this product and feel complete (although I do use others). It has cleared my complexion and left my skin baby-soft and so hydrated! I love it so much and buy it again as soon as I can see the bottom. I cannot run out!!

3 people found this helpful

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LovelySkin Customer

from South Carolina

Verified Purchase

June 26, 2026

Silky moisturizer

This Triple Lipid Restore is my go-to moisturizer - never too heavy - leaves my skin feeling great! A little goes a long way

3 people found this helpful

Profile picture of Kimber.

Kimber

from Texas

Verified Purchase

June 24, 2026

Triple lipid restore 2 4 2

I really like the way this cream makes my face feel. It’s light - yet makes your face feel nice.

2 people found this helpful

Profile picture of Tilly.

Tilly

Age Group: 40-49

Verified Purchase

June 05, 2026

Healed

I ruined my skin barrier by over exfoliating and this healed my skin great! It is a heavier lotion but works great for healing and keeping moisture in skin

5 people found this helpful

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LovelySkin Customer

from California

Age Group: 40-49

Straight Hair

Oily Skin

Verified Purchase

June 04, 2026

Absolutely good product!!

It’s my first time using this moisturizer and I love it! It’s rich but not greasy at all! My skin feels softer and totally moist for the whole day! My fine lines and wrinkles look less visible too! Very happy with the results and will continue to buy this!

4 people found this helpful

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