As a dermatologist-owned retailer, we look for the same things our patients and customers do: science-backed formulas, clinical validation and results that hold up in real life. skinbetter science checks each of these boxes and has a rich history with Dr. Joel Schlessinger via its founder and the scientists who developed it.  We are very proud to now carry this brand.

The brand behind the science

skinbetter science was co-founded in 2016 by pharmaceutical industry professionals and has since become one of the fastest-growing medical-dispensed skin care brands in the United States. Before establishing the brand, its founders spent decades building Medicis Pharmaceutical Corporation into one of the leading specialty pharmaceutical companies in the world, bringing iconic treatments like Restylane, Juvéderm and numerous topical treatments to the dermatology and aesthetics markets. That same biotech-rooted philosophy informs every skinbetter science formula.

Even for all the science, the brand's approach to skin care is refreshingly straightforward: one product can deliver remarkable results, and two to three skinbetter products can change how you feel about your skin. This isn't a brand that demands a ten-step routine. It's one built on targeted, high-performance formulas designed to do more with less. All skinbetter science products are dermatologist tested, paraben free, fragrance free, dye free and cruelty free.

Six standout products, now available at LovelySkin

Skin quality serum: skinbetter science Mystro Active Balance Serum

If your skin looks dull or uneven, this is the serum that helps restore balance. Mystro Active Balance Serum is designed to address multiple skin quality concerns at once, including redness, rough texture, enlarged pores and uneven pigmentation, so your complexion looks clearer, calmer and more radiant over time. Its secret is proprietary P.A.T.H. Technology, a blend of plant-based adaptogens that helps skin cope with the daily stressors that cause these issues in the first place. Antioxidants, including alpha-lipoic acid, astaxanthin and ergothioneine, help defend against environmental aging, while niacinamide and hyaluronic acid support moisture and a stronger skin barrier. In a 12-week dermatologist-led clinical trial, users saw significant improvement across all these concerns after just 8 weeks of twice-daily use, with 98% reporting greater confidence in their skin's appearance.

Moisturizer: skinbetter science Trio Rebalancing Moisture Treatment

Trio Rebalancing Moisture Treatment is a high-performance, triple-action formula designed to bring moisture and hydration balance back to skin, supporting a healthier-looking complexion with improved radiance, suppleness and smoothness. Its patented approach targets three critical elements of natural skin moisturization: natural moisturizing factors, barrier function and hyaluronic acid. Key ingredients include a urea complex for intense moisturization, ceramides and cholesterol to reinforce the skin barrier, and squalane and sodium hyaluronate to support lasting hydration. Despite its deep moisturizing power, the gel-like formulation is surprisingly light and non-comedogenic, making it a fit for all skin types. This product has earned recognition from Allure, DERMASCOPE and beyond.

Retinoid: skinbetter science AlphaRet Overnight Cream

Retinoids are one of the most proven ingredients in skin care for reducing the appearance of fine lines, wrinkles and uneven texture. The problem is that most retinoids cause irritation, redness and peeling, especially for those with sensitive skin. AlphaRet Overnight Cream solves that problem. Its patented AlphaRet Technology bonds a retinoid and an alpha hydroxy acid together into a single molecule, delivering the skin-renewing benefits of a retinoid with dramatically less irritation than traditional formulas. Glycolic acid helps retexturize, a peptide blend supports firmness and elasticity, while ceramides, squalane and hyaluronic acid keep skin hydrated and comfortable throughout the night. It's the number one dermatologist-recommended non-prescription retinoid brand among medical aesthetic skin care brands, with more than 33 awards to its name.

Antioxidant: skinbetter science Alto Advanced Defense and Repair Serum

Every day, environmental stressors like UV exposure, pollution and blue light damage the skin at a cellular level, accelerating the appearance of aging. An antioxidant serum helps neutralize that damage before it shows up as dullness, redness or uneven tone. Alto Advanced Defense and Repair Serum goes further than most. While traditional antioxidant serums rely on vitamins C and E alone, Alto combines them with 17 additional antioxidants for a broader, more comprehensive defense. It also addresses aging that comes from within: its patented Allyl PQQ ingredient targets free radicals generated by the skin's own internal processes, something most serums don't address at all. Supporting ingredients like plankton extract, micrococcus lysate, and licorice extract help the skin recover from sun damage and brighten the complexion over time.

Sunscreen: skinbetter science sunbetter SHEER SPF 56 Mineral Sunscreen Stick

Sunscreen is the single most important step in any anti-aging skin care routine, but it only works if you'll actually use it. sunbetter SHEER SPF 56 Mineral Sunscreen Stick makes that easy. It goes on completely clear with no white cast, blends nicely into all skin tones and fits in your pocket for effortless on-the-go reapplication. Formulated with 100% mineral actives, zinc oxide and titanium dioxide, it provides broad-spectrum protection against UVA and UVB rays without chemical filters. Its patented formula also defends against blue light, pollution, and infrared heat, and is water-resistant for up to 80 minutes, making it just as at home at the gym or on the beach as it is in your morning routine.

Hyaluronic Acid Serum: skinbetter science Ampra Volumizing Macro HA Serum

As skin ages, it naturally loses volume, leading to a hollower, less lifted appearance that other serums and moisturizers simply can't address. Ampra Volumizing Macro HA Serum was specifically developed to tackle this. Most hyaluronic acid in skin care products sits on the surface of the skin, where it can't meaningfully plump from within. Ampra's proprietary "Hyasinc" molecule solves this by bonding alpha-lipoic acid to hyaluronic acid, helping it penetrate deeper into the skin where volume loss actually occurs. In a clinical study, twice-daily use over 12 weeks improved the appearance of skin sagging by 23% and fine lines by 20%, with 98% of participants reporting plumper-looking skin.

Why LovelySkin carries skinbetter science

As the only authorized online retailer of skinbetter science in the United States outside of the brand’s own website, LovelySkin is proud to bring this physician-dispensed brand directly to you. As a practice founded and led by trusted board-certified dermatologists Dr. Joel Schlessinger and Dr. Daniel Schlessinger, we hold every brand we carry to a high clinical standard. skinbetter science earns its place in our offering through rigorous formulation, dermatologist-led clinical trials and a track record of meaningful results. Whether you're beginning your professional skin care journey or looking to build on an existing routine, skinbetter science offers a smart, science-first path forward. For in-office treatments that complement your at-home routine, visit Schlessinger MD.

Shop skinbetter science at LovelySkin

Browse the full skinbetter science collection now available at LovelySkin and find the products that are right for your skin. Questions? Contact our customer care team for personalized recommendations.