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SkinCeuticals Triple Lipid Restore 2:4:2 Anti-Aging Cream

1.6 fl oz
| HSA|FSA Eligible LMN Required
$155.00

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Highlights
  • Smooths the appearance of fine lines
  • Replenishes nourishing lipids
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Product Overview

SkinCeuticals Triple Lipid Restore 2:4:2 refills cellular lipids and nourishes skin. 

SkinCeuticals Triple Lipid Restore 2:4:2 is an anti-aging corrective treatment formulated with essential lipids at a patented percentage of 2% pure ceramides, 4% natural cholesterol and 2% fatty acids. This unique ratio helps restore the skin's moisture barrier, support natural repair processes and correct signs of aging. The result is an improvement in elasticity, moisture levels and radiance, leaving your skin supple, healthy and radiant.

In an eight-week study,SkinCeuticals Triple Lipid Restore users experienced significant improvement in key visible signs of accelerated aging:

  • 66% improvement in smoothness
  • 35% improvement in laxity
  • 20% improvement in evenness
  • 26% improvement in radiance
  • 44% improvement in pore appearance

In a lipidomic study, use of SkinCeuticals Triple Lipid Restore cream resulted in a:

  • 57% increase in ceramides
  • 50% increase in cholesterol
  • 12% increase in fatty acids in the form of triglycerides

Key Ingredients:

  • Essential Lipids: Featuring natural cholesterol, pure ceramides and fatty acids, they restore skin's youthful elasticity and hydration cycles
  • Vitamin E: Supports natural cell repair and reproduction, helping defend against environmental damage
  • Essential Oils: Packed with antioxidants to fight free-radical damage that is responsible for signs of aging

Key Features:

  • Improves the look of texture, skin tone evenness, and overall radiance
  • Shortens the adjustment period to retinoids up to 1 week while reducing dryness
  • Ideal for aging, normal, and dry skin types

Address roughness, dullness and restore facial fullness with SkinCeuticals Triple Lipid Restore 2:4:2.

Highlights

  • Smooths the appearance of fine lines
  • Replenishes nourishing lipids
  • Provides 24 hour hydration

Ingredients

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Return Policy: This product is non-returnable

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ORM-D classified products such as aerosol sprays, nail polish, perfume and products with high alcohol content may only be shipped using a ground method within the Continental US.

Availability: In stock & ready to ship! . Ships within the U.S. only.

Questions & Answers (12)

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Product Specifications

About the Brand

Customer Reviews (2244)

Overall Rating

4.8
Based on 2244 reviews

Review Summary

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2244 Reviews

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LovelySkin Customer

from Virginia

Age Group: 50-59

Mature Skin

Verified Purchase

January 12, 2026

Love This Moisturizer!

After using another brand for years, I tried a sample of Triple Lipid Restore and think I’ve finally found an all-season emollient cream that is surprisingly lightweight and non-greasy. It smells great too!

2 people found this helpful

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Joybc

from Tennessee

Age Group: 60-69

Dry Skin

Verified Purchase

January 12, 2026

Triple lipid restore

This is an exceptional moisturizing treatment. I have only used it for a few weeks, but am very satisfied with Skin Ceuticals. It was recommended by my esthetician & I feel like it is beneficial to mature, dry skin.

1 person found this helpful

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LovelySkin Customer

from Massachusetts

Age Group: 60-69

Verified Purchase

January 10, 2026

Love this moisturizer

I have been using this moisturizer for years and love it. It is very thick and doesn’t absorb quickly into the skin but rather maintains a supple, moisturized feeling for at least 1/2 hour. My skin feels and looks smoother after applying. It is very rich!

0 people found this helpful

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LovelySkin Customer

Age Group: 50-59

Mature Skin

Verified Purchase

January 09, 2026

Very moisturizing

Very moisturizing and foundation goes on smoothly over. Took one star off due to pricing. Way too much.

2 people found this helpful

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LovelySkin Customer

from Georgia

Age Group: 70-79

Wavy Hair

Normal Skin

Verified Purchase

January 06, 2026

SkinCeuticals Triple Lipid Restore

I absolutely am in love with this product! I have tried many other products on my face but nothing gives me the results this does!

1 person found this helpful

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JCRN

from Pennsylvania

Age Group: 50-59

Combination Skin

Verified Purchase

January 06, 2026

The absolute best!

This is the best face cream I have ever used. Rich and creamy but it sinks right in. My face just loves it and the next day my skin is glowing.

0 people found this helpful

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Tuck

from Minnesota

Age Group: 60-69

Straight Hair

Mature Skin

Verified Purchase

January 06, 2026

Excellent moisturizer

I initially received a small sample of this product and noticed when I began using the sample an improvement in the texture and plumpness of my skin. So after sampling I purchased this product. The product is like a thicker heavier moisturizer but absorbs easily and I don’t breakout from it like I usually do with these heavier products. It comes in a ‘tub’ so you need to be careful to not apply more than needed.

0 people found this helpful

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LouiseIP

Age Group: 70-79

Wavy, Color treated hair

Normal Skin

Verified Purchase

December 31, 2025

I love this cream!

I look at myself in a mirror and see a woman 15 years younger only a few days after I started to use this cream

0 people found this helpful

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PNWLady

from Oregon

Age Group: 50-59

Mature Skin

Verified Purchase

December 30, 2025

Very moisturizing

Love this cream. It keeps my skin soft, even with winter wind and overheated rooms.

0 people found this helpful

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ALHB

from Minnesota

Age Group: 50-59

Combination Skin

Verified Purchase

December 28, 2025

Really good moisturizer

I have been using this for about a month now. It definitely is a great moisturizer and makes my skin feel very soft. I haven't noticed any dramatic reduction in fine lines. Seems like there are plenty of options out there for less expensive moisturizers, and as expensive as this is, I likely will switch to something else once I've used up this jar.

0 people found this helpful

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Cinnamon

from California

Age Group: 70-79

Wavy, Dry Hair

Dry Skin

Verified Purchase

December 27, 2025

Classic for a Reason

I tried a jar of this decades ago but my face wasn't old and dry enough to appreciate the wonders of Triple Lipids Restore 2:4:2. I didn't thick my face could get any drier but it did at 70! Gave up using my go to moisturizer and welcomed Skin Ceuticals's classic cream. I use morning and night and my skin smoothly receives foundation and blush.

0 people found this helpful

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LovelySkin Customer

from Arizona

Age Group: 70-79

Straight Hair

Normal Skin

Verified Purchase

December 25, 2025

Amazing results

Started using SkinCeuticals Triple Lipid about a year ago. My skin is so soft now and it appears help with softening my fine facial lines. I apply it daily after vitamin C serum. Also apply it three times a week over Tretinoin. Highly recommend this product.

0 people found this helpful

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AlisonMc1986

from Texas

Age Group: 60-69

Verified Purchase

December 25, 2025

Best winter moisturizer!

This product feels buttery smooth and hydrating and is so worth the splurge especially in the winter months and especially for my mature skin. I’m so glad my aesthetician recommended it! I have sensitive skin and have had zero problems with it. The holiday promo made it easy to add to cart!

0 people found this helpful

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Matty617

Age Group: 60-69

Straight, Color treated hair

Mature Skin

Verified Purchase

December 24, 2025

Thick and feels like good coverage.

I just started using but i bought because i loved the sample. It is so thick and feels so good on the face.

0 people found this helpful

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LovelySkin Customer

from Arizona

Age Group: 70-79

Dry Skin

Verified Purchase

December 24, 2025

Triple lipid restore

I have used Skinceuticals AGE for a long while, recently tried Skinceuticals Triple Lipid Restore and feel this is much more moisturizing for me.

2 people found this helpful

Profile picture of Kperez.

Kperez

Age Group: 30-39

Combination Skin

Verified Purchase

December 24, 2025

El mejor humectante

Llevo alrededor de un mes usándola y me encanta. Es súper ligera, me humecta y el problema que tenía de cara grasosa se me a mejorado en su mayoría! (Tengo rosácea y acné)

0 people found this helpful

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TrishJR

from Wisconsin

Age Group: 70-79

Mature Skin

Verified Purchase

December 23, 2025

Moisturizes A.M. to PM.

Winter in Wisconsin makes my face feeling tight and dry. I chose Triple Lipid Restore 2:4:2 to cover all the bases that my face needs to stay moisturized, soft and supple. December has been very cold and dry and has tested this product’s capabilities. So far, I am pleased. I am not in love with the price point. Unfortunately, it will prevent me from becoming a future fan.

0 people found this helpful

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HomeGirlToo

from Pennsylvania

Age Group: 70-79

Mature Skin

Verified Purchase

December 23, 2025

Wanted to like. Rosacea irritation.

While I would rate this cream as 'ok', not superior (which is something I would expect from the price point), I found it basically inoffensive. Scent-light. Texture-light cream Overall effect-negligible. Irritated my rosacea. Will not repurchase.

0 people found this helpful

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KBCohen

from Florida

Age Group: 60-69

Combination Skin

Verified Purchase

December 18, 2025

Creamy

Love all SkinCeutical products I have tried. This cream is a fantastic addition for my aging skin. Not irritating and absorbs well.

0 people found this helpful

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LovelySkin Customer

Age Group: 70-79

Verified Purchase

December 16, 2025

One of my go-to products

Emollient moisturizers are a must for my aging, drier, sensitive skin, particularly in the winter months, but my skin often rebels by the occasional clogged pore. I have not experienced this with Triple Lipid Restore, which I’ve been using consistently for the last couple of years. I highly recommend it.

0 people found this helpful

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