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SkinCeuticals Triple Lipid Restore 2:4:2 Anti-Aging Cream

1.6 fl oz
| HSA|FSA Eligible LMN Required
$155.00

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Highlights
  • Smooths the appearance of fine lines
  • Replenishes nourishing lipids
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Product Overview

SkinCeuticals Triple Lipid Restore 2:4:2 refills cellular lipids and nourishes skin. 

SkinCeuticals Triple Lipid Restore 2:4:2 is an anti-aging corrective treatment formulated with essential lipids at a patented percentage of 2% pure ceramides, 4% natural cholesterol and 2% fatty acids. This unique ratio helps restore the skin's moisture barrier, support natural repair processes and correct signs of aging. The result is an improvement in elasticity, moisture levels and radiance, leaving your skin supple, healthy and radiant.

In an eight-week study,SkinCeuticals Triple Lipid Restore users experienced significant improvement in key visible signs of accelerated aging:

  • 66% improvement in smoothness
  • 35% improvement in laxity
  • 20% improvement in evenness
  • 26% improvement in radiance
  • 44% improvement in pore appearance

In a lipidomic study, use of SkinCeuticals Triple Lipid Restore cream resulted in a:

  • 57% increase in ceramides
  • 50% increase in cholesterol
  • 12% increase in fatty acids in the form of triglycerides

Key Ingredients:

  • Essential Lipids: Featuring natural cholesterol, pure ceramides and fatty acids, they restore skin's youthful elasticity and hydration cycles
  • Vitamin E: Supports natural cell repair and reproduction, helping defend against environmental damage
  • Essential Oils: Packed with antioxidants to fight free-radical damage that is responsible for signs of aging

Key Features:

  • Improves the look of texture, skin tone evenness, and overall radiance
  • Shortens the adjustment period to retinoids up to 1 week while reducing dryness
  • Ideal for aging, normal, and dry skin types

Address roughness, dullness and restore facial fullness with SkinCeuticals Triple Lipid Restore 2:4:2.

Highlights

  • Smooths the appearance of fine lines
  • Replenishes nourishing lipids
  • Provides 24 hour hydration

Ingredients

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Shipping & Returns

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Return Policy: This product is non-returnable

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Special Shipping Requirements: ORM-D Class
ORM-D classified products such as aerosol sprays, nail polish, perfume and products with high alcohol content may only be shipped using a ground method within the Continental US.

Availability: In stock & ready to ship! . Ships within the U.S. only.

Questions & Answers (12)

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Product Specifications

About the Brand

Customer Reviews (2261)

Overall Rating

4.8
Based on 2261 reviews

Review Summary

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2261 Reviews

Profile picture of Qualingredients.

Qualingredients

from North Carolina

Age Group: 70-79

Wavy, Dry Hair

Combination Skin

Verified Purchase

March 11, 2026

Only one I use

I use Triple Lipid Restore 2:4:2 for my day cream AND night cream. It is excellent. It soaks in beautifully. My skin looks smoother with softer lines.

0 people found this helpful

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PAO

from Washington

Age Group: 40-49

Wavy, Dry Hair

Combination Skin

Verified Purchase

March 10, 2026

Love it

I’ve been using Triple Lipid Restore 2:4:2 from SkinCeuticals for a while now, and it has truly transformed my skin. The texture is rich but absorbs beautifully without feeling greasy. Almost immediately, my skin felt more hydrated, smoother, and noticeably more resilient.

1 person found this helpful

Profile picture of Vena.

Vena

Age Group: 50-59

Dry Skin

Verified Purchase

March 08, 2026

Anti-aging moisturizer for sure

I’ve been using this product for I can’t remember how long. I just can’t find any replacement, it’s a little bit pricy but everytime I use something different, I always come back to this. It corrects the dryness of my face and makes my skin feels soft for a long time. I just wish it helps my bumpy, rough areas on my face.

2 people found this helpful

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Lucy2

from California

Mature Skin

Verified Purchase

March 06, 2026

Moisturizing

I started using this moisturizer about 2 weeks ago. I use SC A.G.E. (at night) so I'm familiar with their products. My face was feeling dry and dehydrated looking. I use SC vitamin c serum during the day for my face so I was looking for a good hydrating moisturizer. This works! Will keep trying it.

1 person found this helpful

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LovelySkin Customer

from California

Verified Purchase

March 03, 2026

Genuine products. Excellent support.

Fast shipping. Good product.

0 people found this helpful

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LovelySkin Customer

from California

Verified Purchase

March 03, 2026

This is a good product. It's well worth buying.

This is a good product. It's well worth buying.

0 people found this helpful

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Awilson4

from Oklahoma

Age Group: 40-49

Straight, Color treated hair

Combination Skin

Verified Purchase

February 24, 2026

Create moisturizer

A little goes a long way. Overall this is one of the best moisturizers I've ever used. Will buy again.

1 person found this helpful

Profile picture of Tt1771.

Tt1771

Age Group: 40-49

Verified Purchase

February 22, 2026

Wonderful product!

I am about to be repurchasing this product soon! It’s become a staple in my daily skincare routine. I love the richness and the difference it’s made in my skin.

0 people found this helpful

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4ever

from North Carolina

Age Group: 40-49

Curly, Dry Hair

Dry Skin

Verified Purchase

February 20, 2026

Great fo dry skin and wrinkles

I have tried many brands including estee lauder, sulwhasoo, and many other korean and luxury moisturizers. I always come back to this. This moisturizer helps with wrinkles and sagging skin. I have been using skin ceuticals for 8 years. I am a 43 yr old smoker and I am always told I look in my 20's. Invest in your skin with this brand. At least 3 products and you will see a difference. This works well with retinol and helps with the dry skin.

2 people found this helpful

Profile picture of Pefunk.

Pefunk

from Texas

Age Group: 60-69

Wavy, Color treated hair

Combination Skin

Verified Purchase

February 18, 2026

Best Anti-aging cream

This is my new night time cream and I am loving the results so far!

2 people found this helpful

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Obaggi

from Puerto Rico

Verified Purchase

February 14, 2026

Skin ceutical

My favorite cream !!!! Y skin feel Amazing !!!

2 people found this helpful

Profile picture of Ginger.

Ginger

from California

Age Group: 80+

Combination Skin

Verified Purchase

February 14, 2026

The Perfect Moisturizer

While my combination skin does not require a moisturizer year long, I do need something as the temperature starts to drop in Southern California during the winter months and can dry out my skin. When this happens, I immediately turn to this moisturizer by Skinceuticals which I have used for years. It continues to be the perfect supplement to my other GREAT products and the final step at night over my SkinMedica TNS Advanced Serum and Retinol and my Skinceuticals C products in the morning. The results are amazing and I love the consistency which is neither too heavy nor too light and the skin drinks it in beautifully leaving a lovely finish to your skin that does not pill after sunscreen or foundation has been applied. I cannot thank Lovelyskin enough for providing these incredible products with amazing discounts throughout the year and realize that part of the reason why I continue to receive compliments on my 80-year old skin is because of the results that these high-quality products deliver!

3 people found this helpful

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LovelySkin Customer

from Massachusetts

Age Group: 30-39

Dry Skin

Verified Purchase

February 10, 2026

Great for sensitive & dry skin

I've been using this moisturizer for years and love it. I have very dry and sensitive skin and this makes my skin so soft.

2 people found this helpful

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AndreaT2552

from Florida

Age Group: 40-49

Straight, Color treated hair

Combination Skin

Verified Purchase

February 01, 2026

In love

I’m 42, I have fine lines and wrinkles. I do get botox and my skin is normal/dry. This stuff is expensive but it’s legit my holy grail! I’m on my 3rd jar. It leaves my skin hydrated, plump, and so youthful looking. Absolutely worth the price.

3 people found this helpful

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LovelySkin Customer

from Missouri

Age Group: 60-69

Straight Hair

Mature Skin

Verified Purchase

January 30, 2026

Triple lipid restore 2:4:2

I absolutely love this!!! I admit I stop for a bit and tried a less expensive version.....never again! it is well worth the price. I would highly recommend this product.

3 people found this helpful

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LovelySkin Customer

from Florida

Verified Purchase

January 29, 2026

Amazing

Restored my dry skin when I returned from Colorado this winter. The best!

1 person found this helpful

Profile picture of Mersk60.

Mersk60

from Pennsylvania

Age Group: 60-69

Curly Hair

Mature Skin

Verified Purchase

January 27, 2026

Best Winter Moisterizer

I have been using Triple Lipid for several years. It is truly one of the best moisturizers to combat the harsh dry winter weather in the Northeast. It is not greasy, and it absorbs into your skin quickly, leaving a natural dewy glow. Works wonders as a base for concealer and foundation. I tend to not use it in the summer because it is on the heavier side of moisturizers and not necessary. A little goes a long way!

2 people found this helpful

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LovelySkin Customer

from Virginia

Age Group: 50-59

Mature Skin

Verified Purchase

January 12, 2026

Love This Moisturizer!

After using another brand for years, I tried a sample of Triple Lipid Restore and think I’ve finally found an all-season emollient cream that is surprisingly lightweight and non-greasy. It smells great too!

6 people found this helpful

Profile picture of Joybc.

Joybc

from Tennessee

Age Group: 60-69

Dry Skin

Verified Purchase

January 12, 2026

Triple lipid restore

This is an exceptional moisturizing treatment. I have only used it for a few weeks, but am very satisfied with Skin Ceuticals. It was recommended by my esthetician & I feel like it is beneficial to mature, dry skin.

4 people found this helpful

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LovelySkin Customer

from Massachusetts

Age Group: 60-69

Verified Purchase

January 10, 2026

Love this moisturizer

I have been using this moisturizer for years and love it. It is very thick and doesn’t absorb quickly into the skin but rather maintains a supple, moisturized feeling for at least 1/2 hour. My skin feels and looks smoother after applying. It is very rich!

2 people found this helpful

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