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SkinCeuticals Triple Lipid Restore 2:4:2 Anti-Aging Cream

1.6 fl oz
| HSA|FSA Eligible LMN Required
$155.00
Highlights
  • Smooths the appearance of fine lines
  • Replenishes nourishing lipids
  • Provides 24 hour hydration
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Product Overview

SkinCeuticals Triple Lipid Restore 2:4:2 refills cellular lipids and nourishes skin. 

SkinCeuticals Triple Lipid Restore 2:4:2 is an anti-aging corrective treatment formulated with essential lipids at a patented percentage of 2% pure ceramides, 4% natural cholesterol and 2% fatty acids. This unique ratio helps restore the skin's moisture barrier, support natural repair processes and correct signs of aging. The result is an improvement in elasticity, moisture levels and radiance, leaving your skin supple, healthy and radiant.

In an eight-week study,SkinCeuticals Triple Lipid Restore users experienced significant improvement in key visible signs of accelerated aging:

  • 66% improvement in smoothness
  • 35% improvement in laxity
  • 20% improvement in evenness
  • 26% improvement in radiance
  • 44% improvement in pore appearance

In a lipidomic study, use of SkinCeuticals Triple Lipid Restore cream resulted in a:

  • 57% increase in ceramides
  • 50% increase in cholesterol
  • 12% increase in fatty acids in the form of triglycerides

Key Ingredients:

  • Essential Lipids: Featuring natural cholesterol, pure ceramides and fatty acids, they restore skin's youthful elasticity and hydration cycles
  • Vitamin E: Supports natural cell repair and reproduction, helping defend against environmental damage
  • Essential Oils: Packed with antioxidants to fight free-radical damage that is responsible for signs of aging

Key Features:

  • Improves the look of texture, skin tone evenness, and overall radiance
  • Shortens the adjustment period to retinoids up to 1 week while reducing dryness
  • Ideal for aging, normal, and dry skin types

Address roughness, dullness and restore facial fullness with SkinCeuticals Triple Lipid Restore 2:4:2.

Highlights

  • Smooths the appearance of fine lines
  • Replenishes nourishing lipids
  • Provides 24 hour hydration

Ingredients

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ORM-D classified products such as aerosol sprays, nail polish, perfume and products with high alcohol content may only be shipped using a ground method within the Continental US.

Availability: In stock & ready to ship! . Ships within the U.S. only.

Questions & Answers (12)

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Product Specifications

About the Brand

Customer Reviews (2221)

Overall Rating

4.8
Based on 2221 reviews

Review Summary

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2221 Reviews

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LovelySkin Customer

from Ohio

Age Group: 50-59

Wavy Hair

Dry Skin

Verified Purchase

December 04, 2025

Great product!

My skin feels so soft! I work outside about 6 to 7 hours a day and the brutally cold temps wreak havoc on my skin. I tried this even tho it’s pricier than what I usually buy but it’s worth every penny. My skin looks better and yes it feels more full - like I’ve gone back 10 years.

0 people found this helpful

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LovelySkin Customer

from Texas

Age Group: 40-49

Verified Purchase

December 03, 2025

Favorite Moisturizer

Worth the price, great moisturizer.

0 people found this helpful

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LovelySkin Customer

from Virginia

Age Group: 60-69

Mature Skin

Verified Purchase

December 01, 2025

Love this stuff

I have sensitive skin prone to rosacea, and I have to be careful about the products I use. This is my go-to, year-round night-time moisturizer. I also sometimes use it for a daytime moisture boost during the dry winter months.

0 people found this helpful

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LovelySkin Customer

from Idaho

Age Group: 50-59

Dry Skin

Verified Purchase

November 28, 2025

Triple Lipid Restore

Like, don’t love. It is great for my sensitive skin in the cold weather, but still getting mild redness and irritation from time-to-time. Could be I’ve only been using it for about 2 weeks?

0 people found this helpful

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KellieSC

from South Carolina

Age Group: 40-49

Combination Skin

Verified Purchase

November 25, 2025

My go-to in the winter

I have mature skin (48yo) that's oily overall but dried out by Tret, and this is my saving grace. It's thick and luscious, and I can't live without it in the winter. I use it at night since it's a little heavy for daytime use. It's definitely worth the splurge!

2 people found this helpful

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LovelySkin Customer

from Tennessee

Age Group: 50-59

Curly, Dry Hair

Combination Skin

Verified Purchase

November 25, 2025

Best on the Market

My dermatologist introduced me to SkinCeuticals years ago. I have tried almost everything and at 57 skincare is work! I was starting to get crepey and itchy skin on my neck. I ran to my dermatologist who thought it was an allergic reaction. Nope, just really dry skin. I started using Tripe Lipid Restore and it disappeared. I have never had a product moisturize the way this does.

3 people found this helpful

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LovelySkin Customer

from California

Age Group: 50-59

Mature Skin

Verified Purchase

November 23, 2025

My Favorite Moisturizer!

Great moisturizer! I use it after hyaluronic and before bed so it has time to fully absorb. I tend to get oily during the day, so for me its a bit heavy for day use unless my skin is dryer than normal. Its a great nighttime moisturizer for me and makes my skin glow.

0 people found this helpful

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LovelySkin Customer

from Pennsylvania

Age Group: 60-69

Straight, Color treated hair

Combination Skin

Verified Purchase

November 21, 2025

Great cream

Love it, smells so good! Best cream I tried for a long time.

0 people found this helpful

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Tal

from California

Age Group: 50-59

Verified Purchase

November 20, 2025

Rachel W

I wanted to love this as I’ve only read wonderful reviews, but it made me break out and it was not moisturizing enough for my dry skin so I will not purchase it again..

2 people found this helpful

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LovelySkin Customer

from Nebraska

Age Group: 20-29

Combination Skin

Verified Purchase

November 20, 2025

Nice Product but Not Worth the Price

This was one of my first SkinCeuticals products I tried. As much as I love the calming scent of it and easy application, it does have a bit of a greasy feel on the skin that lasts longer than I like. I really only could use it at night because of it's heaviness and greasiness which is expected from an anti-aging lipid cream. I liked how it kept my skin moisturized. I just wish it wasn't so expensive. I've tried all sorts of products similar to this and one that it reminds me of is a certain luxury moisturizing cream. Comparing the two, I actually like this SkinCeuticals one better, but it's still too pricy for me to drop $160 on every 3 months.

3 people found this helpful

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MTR

from Massachusetts

Age Group: 80+

Wavy, Color treated hair

Mature Skin

Verified Purchase

November 16, 2025

Triple Lipid Restore 2:4:2 Cream

I have used it daily for years after Vit C

1 person found this helpful

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Grannie

from Tennessee

Age Group: 80+

Verified Purchase

November 16, 2025

great cream

I have used this for years. Love this product

0 people found this helpful

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LovelySkin Customer

from Texas

Age Group: 70-79

Straight Hair

Dry Skin

Verified Purchase

November 15, 2025

Triple Lipid

Wonderful moisturizer! It’s the right amount of consistency, takes only a smidge and I never feel the need to reapply. It’s smells very clean and fresh.

3 people found this helpful

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LovelySkin Customer

from Florida

Verified Purchase

November 14, 2025

My Favorite

This is my favorite anti-aging product. Love the way it feels on my skin and the fragrance is lovely.

0 people found this helpful

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LovelySkin Customer

Age Group: 30-39

Normal Skin

Verified Purchase

November 10, 2025

Great night cream!

Bought this as my new night cream and have been loving it! Great texture; not too rich and not too thin, and feels hydrating. Seems like my newly-formed fine lines have been softer when I wake up in the morning.

1 person found this helpful

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PalmettoGirl

from South Carolina

Age Group: 50-59

Wavy, Color treated hair

Combination Skin

Verified Purchase

November 08, 2025

Light and Airy

Light airy moisturizer. Doesn’t feel heavy during the day

0 people found this helpful

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Slossie1

from New Jersey

Age Group: 60-69

Straight Hair

Mature Skin

Verified Purchase

November 06, 2025

Lovely product!

I love this product as it makes my skin feel very soft n the smell is like i just left a spa!! Its a relaxing feel n a great treat for your face.. I do love it! I was hesitant to buy it due to the price n i usually use a bit more than i should, again love the scent n the way it feels on my face! Its such a treat i feel when i put this on n it takes me to a relaxing state n great for my well being without going for a facial n leaving my home! Sincerely, carol s.

1 person found this helpful

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LovelySkin Customer

from Arizona

Age Group: 60-69

Verified Purchase

November 05, 2025

The best product of SkinCeuticals

Every great company makes at least one great product. Porsche made 911. SkinCeuticals created Triple Lipid.

2 people found this helpful

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LovelySkin Customer

from Nebraska

Verified Purchase

November 05, 2025

Light and nice

Light but very powerful moisturizer

0 people found this helpful

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Essence

from California

Age Group: 60-69

Verified Purchase

November 05, 2025

Triple Lipid Restore

Excellent cream for my sensitive skin. I didn’t know how it was going to turn out but so far so good. No issues. Love the cream and how it goes in smoothly.

1 person found this helpful

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