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SkinCeuticals Triple Lipid Restore 2:4:2 Anti-Aging Cream

1.6 fl oz
| HSA/FSA Eligible LMN Required
$155.00
Highlights
  • Smooths the appearance of fine lines
  • Replenishes nourishing lipids
  • Provides 24 hour hydration

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Product Overview

SkinCeuticals Triple Lipid Restore 2:4:2 refills cellular lipids and nourishes skin. 

SkinCeuticals Triple Lipid Restore 2:4:2 is an anti-aging corrective treatment formulated with essential lipids at a patented percentage of 2% pure ceramides, 4% natural cholesterol and 2% fatty acids. This unique ratio helps restore the skin's moisture barrier, support natural repair processes and correct signs of aging. The result is an improvement in elasticity, moisture levels and radiance, leaving your skin supple, healthy and radiant.

In an eight-week study, SkinCeuticals Triple Lipid Restore users experienced significant improvement in key visible signs of accelerated aging:

  • 66% improvement in smoothness
  • 35% improvement in laxity
  • 20% improvement in evenness
  • 26% improvement in radiance
  • 44% improvement in pore appearance

In a lipidomic study, use of SkinCeuticals Triple Lipid Restore cream resulted in a:

  • 57% increase in ceramides
  • 50% increase in cholesterol
  • 12% increase in fatty acids in the form of triglycerides

Key Ingredients:

  • Essential Lipids: Featuring natural cholesterol, pure ceramides and fatty acids, they restore skin's youthful elasticity and hydration cycles
  • Vitamin E: Supports natural cell repair and reproduction, helping defend against environmental damage
  • Essential Oils: Packed with antioxidants to fight free-radical damage that is responsible for signs of aging

Key Features:

  • Improves the look of texture, skin tone evenness, and overall radiance
  • Shortens the adjustment period to retinoids up to 1 week while reducing dryness
  • Ideal for aging, normal, and dry skin types

Address roughness, dullness and restore facial fullness with SkinCeuticals Triple Lipid Restore 2:4:2.

Highlights

  • Smooths the appearance of fine lines
  • Replenishes nourishing lipids
  • Provides 24 hour hydration

Ingredients

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ORM-D classified products such as aerosol sprays, nail polish, perfume and products with high alcohol content may only be shipped using a ground method within the Continental US.

Availability: In stock & ready to ship! . Ships within the U.S. only.

Questions & Answers (12)

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Product Specifications

About the Brand

Customer Reviews (2305)

Overall Rating

4.8
Based on 2305 reviews

Review Summary

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2305 Reviews

Profile picture of Rainydayz.

Rainydayz

from Oregon

Age Group: 50-59

Verified Purchase

July 27, 2026

All time Fav!

This is my number one all time favorite moisturizer. It provides amazing hydration and is no doubt worth the cost for youthful skin. I use it at nighttime only now, because there are so many great moisturizers to alternate from Skin Ceuticals Brand purchased from Lovely Skin who carries the best selection!

0 people found this helpful

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LovelySkin Customer

from Massachusetts

Age Group: 60-69

Mature Skin

Verified Purchase

July 23, 2026

SkinCeuticals

I switched back and I’m glad I did. My skin feels so good.

2 people found this helpful

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LovelySkin Customer

from Maryland

Age Group: 70-79

Mature Skin

Verified Purchase

July 20, 2026

Best moisturizer

I love this product. It keeps my face moisturized all day long. Although it’s expensive, a little goes a long way.

2 people found this helpful

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LovelySkin Customer

from Florida

Age Group: 60-69

Verified Purchase

July 18, 2026

Expected more

From the reviews and the price, I expected more from this moisturizer. It’s fine and right after I put it on my face, my face feels softer, however, that “moisture” doesn’t seem much different other than right away. It’s only been a couple of weeks, but unless all of a sudden there’s a drastic change in my skin, I won’t be purchasing this again. Very disappointing.

2 people found this helpful

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Karen7

from California

Age Group: 80+

Straight, Color treated hair

Mature Skin

Verified Purchase

July 17, 2026

Very Best SkinCeutical Moisturizer

I love my SkinCeutical Triple Liquid Restore moisturizer so much that I buy ahead so I never run out. I am 86 years old and I have been using SkinCeutical products especially my Triple Liquid Restore for years. I always hear how great my skin looks. Whenever I decide to try something new, I always come right back to Triple Liquid Restore Moisturizer. I also purchase all my skin care from Lovely Skin. Thank You So Much

2 people found this helpful

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LovelySkin Customer

from New York

Age Group: 60-69

Wavy, Color treated hair

Normal Skin

Verified Purchase

July 16, 2026

Love it

I have been using Triple Lipid for many months now and I have seen great results I use it as my final product on my fave I highly recommend this I am 63 years old and my skin looks and feels great

2 people found this helpful

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Pinktiger

from Alabama

Age Group: 60-69

Verified Purchase

July 05, 2026

Wow!

This really does make my retinol using skin more supple and moisturized. Also improves my wrinkles and fine lines.

2 people found this helpful

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LovelySkin Customer

from Illinois

Verified Purchase

July 05, 2026

Love it

Works great!

2 people found this helpful

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MFender

from Georgia

Age Group: 40-49

Verified Purchase

July 02, 2026

Buy it!

This product has been so amazing for my skin. I could use just this product and feel complete (although I do use others). It has cleared my complexion and left my skin baby-soft and so hydrated! I love it so much and buy it again as soon as I can see the bottom. I cannot run out!!

2 people found this helpful

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LovelySkin Customer

from South Carolina

Verified Purchase

June 26, 2026

Silky moisturizer

This Triple Lipid Restore is my go-to moisturizer - never too heavy - leaves my skin feeling great! A little goes a long way

2 people found this helpful

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Kimber

from Texas

Verified Purchase

June 24, 2026

Triple lipid restore 2 4 2

I really like the way this cream makes my face feel. It’s light - yet makes your face feel nice.

1 person found this helpful

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Tilly

Age Group: 40-49

Verified Purchase

June 05, 2026

Healed

I ruined my skin barrier by over exfoliating and this healed my skin great! It is a heavier lotion but works great for healing and keeping moisture in skin

4 people found this helpful

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LovelySkin Customer

from California

Age Group: 40-49

Straight Hair

Oily Skin

Verified Purchase

June 04, 2026

Absolutely good product!!

It’s my first time using this moisturizer and I love it! It’s rich but not greasy at all! My skin feels softer and totally moist for the whole day! My fine lines and wrinkles look less visible too! Very happy with the results and will continue to buy this!

4 people found this helpful

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LovelySkin Customer

from Kentucky

Age Group: 70-79

Verified Purchase

June 01, 2026

Triple Lipid restore 2:4:2 anti-aging cream

Made my face break out like it did when I was a teenager.

7 people found this helpful

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LovelySkin Customer

from California

Age Group: 40-49

Normal Skin

Verified Purchase

May 24, 2026

A skincare staple

Love SkinCeuticals Triple Lipid Restore 2:4:2! It's part of my daily routine - morning and night. Goes on smoothly, feels refreshing and moisturizing; not greasy at all. I always pair it CE Ferulic and Photo Corrective Gel - also by SkinCeuticals. All the good reviews about this product are here for a reason. Solid daily moisturizer that keeps us youthful and moisturized!

6 people found this helpful

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LovelySkin Customer

Verified Purchase

May 22, 2026

Fantastic

Great moisturizer for very dry skin. My only bad thing to say is the bottle doesn’t last long for the price

8 people found this helpful

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KMill

from Illinois

Verified Purchase

May 21, 2026

Luxurious

This moisturizer feels amazing. It is so soft and the texture is like butter. So worth the cost!!

7 people found this helpful

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LovelySkin Customer

from Maryland

Age Group: 70-79

Straight Hair

Mature Skin

Verified Purchase

May 21, 2026

Triple Lipid Restore

This is my everyday treatment. I use after my Skin Ceuticals vitamin C. At 75 I continue to receive compliments on my young looking skin.

3 people found this helpful

Profile picture of Terl.

Terl

from Texas

Age Group: 60-69

Mature Skin

Verified Purchase

May 21, 2026

Effective anti-aging emollient

This is my first time using this cream and it does not disappoint. It’s rich but not greasy. My skin feels softer and has a glow. Very happy with the results!

3 people found this helpful

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LovelySkin Customer

from Minnesota

Age Group: 50-59

Mature Skin

Verified Purchase

May 13, 2026

My favorite product ever purchased

Wow…I wish I knew about this earlier. I have struggled to use tretinoin my entire adult life. This cream completely suppresses any irritation from tretinoin. This is a product that I will always repurchase and make sure that I am never without. I have been to so many dermatologists throughout my life and can’t believe they never shared information about this amazing product with me. Better late than never discovery

3 people found this helpful

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