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SkinMedica Retinol Complex 0.25

1.0 oz
| HSA|FSA Eligible LMN Required
$48.00
$64.00 25% Off
Highlights
  • Paraben-free
  • Encourages cell turnover
  • Fades signs of aging and damage
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Product Overview

Renew the complexion with SkinMedica Retinol Complex 0.25.

As skin begins to age, everyone should include a retinol product in their skin care routine to encourage cell turnover. SkinMedica Retinol Complex 0.25 contains a lower concentration of this anti-aging ingredient so it is ideal for anyone who has never used a retinol product. The formula encourages cell turnover which fades the look of fines lines, wrinkles and dark spots. Adding this anti-aging product to your routine will create a smoother texture and clearer skin tone. The formula contains soothing ingredients that help minimize irritation, flaking and redness that is caused by many retinol products. Antioxidants neutralize free radicals to help reduce the appearance of new signs of aging. 

Key Features: 

  • 0.25% retinol exfoliates and encourages cell renewal 
  • Bisabolol improves hydration and reduces inflammation 
  • Antioxidants defend against free radicals that cause signs of aging and damage 

Highlights

  • Paraben-free
  • Encourages cell turnover
  • Fades signs of aging and damage

Ingredients

Directions

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Product Specifications

About the Brand

Customer Reviews (208)

Overall Rating

4.7
Based on 208 reviews

Review Summary

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208 Reviews

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LovelySkin Customer

from Illinois

Verified Purchase

December 02, 2025

Effective Retinol for Sensitive Skin!

I love how gentle yet effective this retinol is. It helps with fine lines, uneven skin tone, and overall skin texture. I noticed improvements within a month and my skin feels soft, smooth, and radiant.

0 people found this helpful

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Grandmama

from Florida

Age Group: 70-79

Mature Skin

Verified Purchase

November 22, 2025

Just strong enough!

At my age (71) I know retinol should be a part of my skin care regimen. This product gives me a healthy dose of retinol without the side effects of a stronger formula with more retinol. Any product above 25% retinol turns my skin red and flaky. This does not. It goes on like a lotion and even feels moisturizing!

1 person found this helpful

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LovelySkin Customer

from California

Verified Purchase

November 15, 2025

Retinol

Great product!

0 people found this helpful

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KonaSunshine

from Hawaii

Age Group: 70-79

Curly Hair

Normal Skin

Verified Purchase

November 08, 2025

Lovely Skin

Literally. I have never used a retinol product before, so I wanted to start out with the lowest formula and work my way up. I have been using it every other night with SkinMedica’s TNS Advanced Serum. I think it is the perfect combination of products. I didn’t want to worry about redness and peeling which I have heard can occur whenever using a retinol product. I am on my second bottle of retinol now and I think I will be using this religiously forever. I have a friend who uses this product and has been for years and she suggested it to me. If her skin is any example, I will be using this forever.

0 people found this helpful

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LovelySkin Customer

from Iowa

Age Group: 50-59

Verified Purchase

October 22, 2025

Good option for starting on retinol

Starting on retinol can be very drying and this is a good starting point for your skin to gain tolerance.

0 people found this helpful

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LovelySkin Customer

from Oregon

Age Group: 60-69

Wavy Hair

Mature Skin

Verified Purchase

August 08, 2025

Good

So far so good. It will take time to see if there are results, but I like that it doesn’t have a strong fragrance and I have had no adverse skin reactions.

1 person found this helpful

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AustinT

from Texas

Age Group: 70-79

Wavy, Color treated hair

Combination Skin

Verified Purchase

July 16, 2025

Love this product!

I use this product nightly and it has made a real difference in my skin! Love it!

0 people found this helpful

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LovelySkin Customer

Verified Purchase

June 23, 2025

Love

This is my favorite retinol. Was recommended a few years ago and I have never looked back. As all retinols you need to build up slowly. I started with the every other night and sandwich method but now I can use it nightly without skin irritation.

0 people found this helpful

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LovelySkin Customer

Verified Purchase

June 07, 2025

SkinMedica Retinol Complex 0.25

SkinMedica products are awesome. This retinol is one of the best I've used. In the morning my face is super soft and supple; not too strong, yet effective.

0 people found this helpful

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LovelySkin Customer

Verified Purchase

March 24, 2025

Only retinol for me!

I have tried several retinols, many at far more expensive price points, with no success. My sensitive, combination, acne prone skin always reacted poorly. I thought that retinol just wasn’t in the cards for me. I am creeping closer to 40 and decided I needed to give retinol another try. I wish I would have tried this sooner! I have been using it for 6 weeks without issue. No skin irritation or burning whatsoever. I did start slowly with once per week usage, building up to now using every other night. I am using this more preventatively, so the .25 provides the results I am looking for. I follow it up with a hyaluronic serum and a medium-weight moisturizer.

2 people found this helpful

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LovelySkin Customer

Verified Purchase

December 24, 2024

Just the right amount of retinol

Love this retinol. Just the right amount so it’s not too strong but you can use it every other day! Love the difference I see in my skin. Skin tone and texture has improved. Lightened dark spots.

1 person found this helpful

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LovelySkin Customer

Verified Purchase

October 28, 2024

Very pleased so far

I’ve used many skinmedica products, though right now I happen to be using a different similar line other than this product. I purchased the Retinol Complex .25 specifically for its very low percentage retinol. My rosacea-prone, post-meno skin is easily irritated by strong actives, which has prevented retinol in the past. I use a good routine with Vit C, hyaluronic acid and sunscreen in the morning and glycolic acid at night a few times a week. At 54 my skin does look younger than my age. But I wanted to introduce retinol to treat sun damage and prevent deeper wrinkles. After several weeks use 2x/wk, this is the perfect starter retinol. Not a single day of irritation and noticeably brighter skin that can only be attributed to this one change. Worth the money.

1 person found this helpful

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LovelySkin Customer

Verified Purchase

October 27, 2024

Great for starting low

Wonderful product to start low with retinol

0 people found this helpful

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LovelySkin Customer

Verified Purchase

October 26, 2024

Very lightweight and non-drying

Very good for beginners. No strange smell and easily absorbs into skin. Loving this so far.

1 person found this helpful

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LovelySkin Customer

Verified Purchase

October 17, 2024

SkinMedica Retinol Complex 0.25

I’ve been using this product every night for a few years. My skin is smooth and people often tell me I look younger than I am. I will continue to use it.

0 people found this helpful

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LovelySkin Customer

Verified Purchase

October 11, 2024

perfect for dry, sensitive skin

I recently learned that gain more benefit from using a lower dose of retinol on a daily basis, than a large dose that could irritate your skin every once in a while. I have consistently been able to use this retinol three days a week without issue. I could probably up it to daily.

1 person found this helpful

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LovelySkin Customer

Verified Purchase

October 07, 2024

Gentle

No skin disturbance, absorbs quickly. No problems using this.

1 person found this helpful

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Skinlover

Verified Purchase

August 14, 2024

Retinol .25

I have been using this all summer. I use it every other night. My skin has been fairly clear and some congested pores have opened up and cleared up. I have not had any issues with irritation at all. I had previously been using a lot of products (quality but extra strong) and my skin, which is combination, reacted with red irritated patches. So I backed off and began using a much milder combination and all irritation subsided while still helping my skin to remain clear and smooth. For reference, I am 69 and have enjoyed my time in the sun throughout my youth. I am moving up to the next level, and hopefully my skin will continue to tolerate and I will see continued improvement.

0 people found this helpful

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LovelySkin Customer

Verified Purchase

August 12, 2024

great

This is a great starter retinol.

0 people found this helpful

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Noni

Verified Purchase

July 20, 2024

Nothing to report

I've been using this for a few weeks now, and I cannot say I have noticed any difference. In one way, that's good because my sensitive skin hasn't had a reaction to it. On the other hand, my skin looks dull and a little dryer. I definitely will not be repurchasing it.

0 people found this helpful

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