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SkinMedica TNS® Advanced+ Serum - 3 Pack

 
| HSA/FSA Eligible LMN Required
$885.00

Special Offer: 20% off use code SMEDF2026

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Highlights
  • Fragrance-free
  • Boosts collagen and elastin production
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Product Overview

SkinMedica TNS Advanced+ Serum - 3 Pack offers the classic formula, now supercharged.

This SkinMedica serum builds upon the legendary results of its predecessor for powerful anti-aging. Every piece of the TNS Essential serum, from the peptides to the growth factors has been rethought and amplified. Because of this, it's even better at softening wrinkles, diminishing dark spots and addressing other signs of aging.

Formulated with TNS-MR, the next-generation growth factor blend, this serum acts on multiple levels of the skin to achieve the best results. Additionally, Renessensce (RSC) Advanced, a highly active blend of botanicals, peptides and marine extracts, supports skin renewal for plumper, more youthful skin, delivering results in as little as two weeks.

Set Includes:

  • SkinMedica TNS Advanced+ Serum (3 x 1.0 fl oz)

Key Features:

  • New Innovative 2 Tripeptide Complex visibly firms and smooths fine lines and wrinkles
  • Potent blend of Spanish Marine extract and Green Microalgae builds collagen and supports skin's repair process
  • Provides antioxidants for improved defense against environmental stress
  • Visibily lifts sagging skin while improving skin tone and texture
  • In studies, users felt they looked up to 6 years younger after 12 weeks
  • Fragrance-free and paraben-free

Experience a breakthrough in anti-aging science with SkinMedica TNS Advanced+ Serum.

Highlights

  • Fragrance-free
  • Boosts collagen and elastin production
  • Contains growth factors

Ingredients

Directions

Shipping & Returns

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ORM-D classified products such as aerosol sprays, nail polish, perfume and products with high alcohol content may only be shipped using a ground method within the Continental US.

Availability: In stock & ready to ship! .

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Product Specifications

About the Brand

Customer Reviews (2039)

Overall Rating

4.6
Based on 2039 reviews

Review Summary

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2039 Reviews

Profile picture of BTrapp.

BTrapp

from Louisiana

Age Group: 70-79

Mature Skin

Verified Purchase

September 18, 2026

Nothing better

I have been using this for years even before the package change. I tried cheaper products and some near the same cost but I keep coming back to this. It works for me. My lines are less noticeable and skin tone brighter when this is my product.

1 person found this helpful

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LovelySkin Customer

from Pennsylvania

Age Group: 50-59

Verified Purchase

September 18, 2026

Can’t Go Without-

I’ve been using this for decades and I swear by it. Excellent product extremely effective can’t live without. You will see results. xx

1 person found this helpful

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LovelySkin Customer

from California

Verified Purchase

September 18, 2026

Overpriced

The serums feel heavy and don't absorb well. Nearly no results. Overpriced. Worst of all, it is impossible to dispense both serums at a time! Totally defective design. May I have a refund, please?

1 person found this helpful

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LovelySkin Customer

from Minnesota

Age Group: 40-49

Verified Purchase

September 14, 2026

My skin has never looked better!

Within two weeks my skin has completely transformed.

1 person found this helpful

Profile picture of LesPie.

LesPie

from Tennessee

Age Group: 60-69

Curly, Dry Hair

Mature Skin

Verified Purchase

September 13, 2026

Nice product!

I have used TNS serum on and off over the years and in the recent months I have started using it again. I can really see a difference in my skins texture and firmness. It is pricy but it is truly a quality product, especially for my mature skin.

1 person found this helpful

Profile picture of ASK.

ASK

from Nebraska

Verified Purchase

September 11, 2026

AK

Loving it so far! Been using for almost 3 weeks and my skin already seems brighter!

1 person found this helpful

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LovelySkin Customer

from Washington

Verified Purchase

September 07, 2026

Great Transaction

Product sent/recieved in a timely manner, it was fresh and authentic.

1 person found this helpful

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LovelySkin Customer

from Pennsylvania

Verified Purchase

September 05, 2026

Top tier

So I’ve been using this product for about two months and I’ve seen a slight difference in my skin. Where I see a major difference is on the back of the hand that I use to mix together looks much more smooth and less creepy.

1 person found this helpful

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LovelySkin Customer

from New York

Age Group: 50-59

Wavy, Color treated hair

Normal Skin

Verified Purchase

September 03, 2026

Keeps its promise

I’m on my second bottle of SkinMedica TNS Advanced Serum and I’ve noticed a change in the firmness and elasticity of my skin, especially around the mouth, chin, and neck. It’s great for hydrating and plumping too, smoothing fine lines. Both times I’ve purchased this serum I’ve been able to catch it at a great price. I love that I can use my Alle rewards towards the purchase. I like pairing it with Skinmedica H5 Collagen. My skin feels so pampered!

1 person found this helpful

Profile picture of MartinLanzas.

MartinLanzas

from Texas

Age Group: 30-39

Straight hair, Dry/flaky scalp

Normal Skin

Verified Purchase

August 31, 2026

Love this serum!

I love this serum so much! and I love that lovelyskin has it on sale pretty often

1 person found this helpful

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LovelySkin Customer

from Florida

Age Group: 50-59

Mature Skin

Verified Purchase

August 29, 2026

Safe for sensitive skin

Finally an anti aging treatment that works for sensitive skin. I have been using for 6 weeks now and notice an improvement in fines lines and some improvement with firming. I will be purchasing again.

0 people found this helpful

Profile picture of Crystalm.

Crystalm

Age Group: 40-49

Mature Skin

Verified Purchase

August 29, 2026

Dried my skin out

Dried my skin barrier will discontinue use amd stick with recovery i perfer recovery over advance

0 people found this helpful

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LovelySkin Customer

from Massachusetts

Age Group: 50-59

Verified Purchase

August 24, 2026

TNS

I’ve been using SkinMedica TNS Advanced+ Serum as part of my daily skincare routine and really enjoy it. It absorbs quickly, layers well with my other products, and doesn’t feel heavy or sticky. My skin feels smoother and more hydrated, It’s definitely an investment, but so far I’m very happy with it.

5 people found this helpful

Profile picture of MariaGG.

MariaGG

from North Carolina

Age Group: 60-69

Mature Skin

Verified Purchase

August 22, 2026

Effective and easy to use

The cream is easy to apply and so far seems effective. When I apply it, I feel like the firmness of my skin is improved. I am very sensitive to smells. This cream doesn’t smell, which makes it even more valuable for me. I use it with a moisturizer. Use it twice a day every other day. On days off I use a different brand. And I will be definitely reordering.

4 people found this helpful

Profile picture of LovelyDove.

LovelyDove

from New York

Verified Purchase

August 07, 2026

Good stuff

‘Nuff said

7 people found this helpful

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LovelySkin Customer

Verified Purchase

August 04, 2026

SkinMedica TNS Advanced Serum

I have used SkinMedica products for many years. The SkinMedica TNS Advanced Serum is one of the best products I have incorporated into my skincare routine. This product brightens and plumps my skin and aids with fine lines. It also feels amazing on my face.

4 people found this helpful

Profile picture of KJTS.

KJTS

from Texas

Age Group: 50-59

Wavy, Color treated hair

Dry Skin

Verified Purchase

August 04, 2026

Amazing!

I have used this serum for years and it leaves my skin glowing! I love the new packaging!

2 people found this helpful

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LovelySkin Customer

from Ohio

Age Group: 50-59

Wavy Hair

Combination Skin

Verified Purchase

August 03, 2026

TNS Advance + Serum

I used TNS Advance + Serum for years & years directly through the Skinmedica site. I stopped because I couldn’t justify the extra $295.00 every 2 months any longer. I started noticing the difference in my skin within six months of discontinuing the product. I just looked much older and not as fresh. The product really works, thank God I found lovely skin. It’s more affordable and I’m getting my skin back to what I remember and also because it’s more affordable, I can try other skinmedica products.

5 people found this helpful

Profile picture of TaraIsGreat.

TaraIsGreat

from New Jersey

Age Group: 50-59

Straight Hair

Mature Skin

Verified Purchase

July 31, 2026

Excellent

An esthetician introduced this to me a few years ago and I had forgotten just how good it is. Almost immediately you will see an improvement in your skin's texture. I put it on immediately after cleansing and let it seep in for a few minutes before following with moisturizer. This is a superior serum. It is definitely worth the price. Put it on auto ship for the discount. Your skin will thank you.

2 people found this helpful

Profile picture of shebail.

shebail

from Virginia

Age Group: 60-69

Straight Hair

Combination Skin

Verified Purchase

July 31, 2026

TNS Advance Serum

I have used this product for a few years as part of my skin care routine and see visible results.

1 person found this helpful

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