SkinMedica TNS Advanced+ Serum - 3 Pack

Product Overview

SkinMedica TNS Advanced+ Serum - 3 Pack offers the classic formula, now supercharged.

This SkinMedica serum builds upon the legendary results of its predecessor for powerful anti-aging. Every piece of the TNS Essential serum, from the peptides to the growth factors has been rethought and amplified. Because of this, it's even better at softening wrinkles, diminishing dark spots and addressing other signs of aging.

Formulated with TNS-MR, the next-generation growth factor blend, this serum acts on multiple levels of the skin to achieve the best results. Additionally, Renessensce (RSC) Advanced, a highly active blend of botanicals, peptides and marine extracts, supports skin renewal for plumper, more youthful skin, delivering results in as little as two weeks.

Set Includes:

SkinMedica TNS Advanced+ Serum (3 x 1.0 fl oz)

Key Features:

New Innovative 2 Tripeptide Complex visibly firms and smooths fine lines and wrinkles
Potent blend of Spanish Marine extract and Green Microalgae builds collagen and supports skin's repair process
Provides antioxidants for improved defense against environmental stress
Visibily lifts sagging skin while improving skin tone and texture
In studies, users felt they looked up to 6 years younger after 12 weeks
Fragrance-free and paraben-free

Experience a breakthrough in anti-aging science with SkinMedica TNS Advanced+ Serum.

Highlights

Fragrance-free
Boosts collagen and elastin production
Contains growth factors

Ingredients

Directions

Shipping & Returns

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Return Policy: View Our Return Policy

Availability: In stock & ready to ship! .

Questions & Answers

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Product Specifications

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About the Brand

Customer Reviews (1925)

Overall Rating

4.6

Based on 1925 reviews

Review Summary

5 Stars

1536

4 Stars

234

3 Stars

2 Stars

1 Star

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1925 Reviews

from South Carolina

Age Group: 40-49

Wavy, Color treated hair

Mature Skin

Verified Purchase

February 04, 2026

Funky Smell & Bad Pump

I wanted to love this, but the funky smell & malfunctioning pump were enough to override the positives. You can take the top apart and get more even distribution, but you shouldn’t have to. It definitely wastes some product until you get the pump working right. The smell is just plain bad, like something may have gone wrong. I also found that a different product gives my skin a better texture & glow, as a 49 year old dealing with some aging issues to address. It has growth factors as well, without the pump & smell issues.

0 people found this helpful

LovelySkin Customer

from Virginia

Verified Purchase

January 30, 2026

Amazing

The product is amazing I seen results in just a few weeks!

0 people found this helpful

JenniferJW

from Louisiana

Age Group: 50-59

Straight Hair

Mature Skin

Verified Purchase

January 28, 2026

SkinMedica TNS Advanced Serum

I love this product! I use it day and night and take it with me on all of my travels. I use it on the back of my hands too. Truly changes the appearance of your skin. Smoother, visible signs in texture and firmness.

1 person found this helpful

MABE

Age Group: 60-69

Wavy, Dry Hair

Combination Skin

Verified Purchase

January 25, 2026

Great Product at a Great Price

The TNS serum makes fine lines look way less noticeable and has a tightening effect. I like the feel. I got 3 bottles for the price of 2, which was a great deal, since this product is somewhat pricey!

0 people found this helpful

Finn

from California

Verified Purchase

January 25, 2026

a must have serum

I highly recommend this product. my skin never have looked so gorgeous and plump. This is a product i can’t live without!

1 person found this helpful

Awilson4

from Oklahoma

Age Group: 40-49

Straight, Color treated hair

Normal Skin

Verified Purchase

January 24, 2026

Still unsure

I really wanted to add an EGF into my routine and gave this a try. I really like the consistency and the way it lays on my skin but I haven't really noticed any changes or positive improvements to my skin. I think you have to give it every 60 days but based off of the cost I don't think I'm going to purchase this again. I do use other skin medical products I just don't think this one's for me.

2 people found this helpful

LovelySkin Customer

from Massachusetts

Age Group: 40-49

Wavy Hair

Combination Skin

Verified Purchase

January 22, 2026

Dedicated TNS Advanced+ Serum user!

I've been using this serum every night for years and have really seen results. It's pricey so I always keep my eye out for any sales. This 3-pack was a good deal!

0 people found this helpful

LovelySkin Customer

from California

Verified Purchase

January 21, 2026

Great purchase!

I’m so happy knowing I have an extra bottle of TNS! Excellent, superb product!

0 people found this helpful

HeidiL

Age Group: 30-39

Wavy Hair

Dry Skin

Verified Purchase

January 21, 2026

One of My Favorites

I use this nightly as part of my routine to age gracefully, and it has become a must have for me. My skin feels smoother, firmer, and more refreshed, and I love knowing I am investing in long term skin health.

1 person found this helpful

ROMANHOLIDAY

Age Group: 70-79

Mature Skin

Verified Purchase

January 20, 2026

TNS Advanced Miracle Prodent

I haven't written a review about the new packaging of this supurb product. The new pump system is a vast imporvement over the old bottle. It is much easier to select each pump for distribution and they don't clog the way the old ones used to, The product is always spectacular - I have been using is for years. and although I recently turned 75, people always comment that I look in my 50s!! Try the new packaging and see for yourself!

5 people found this helpful

LovelySkin Customer

from Florida

Age Group: 70-79

Wavy hair, Dry/flaky scalp

Mature Skin

Verified Purchase

January 17, 2026

TNS Advanced Serum

The new packaging is fabulous!!!! It makes way more sense than the other packaging. It solves the problems that were present with the old packaging like uneven amounts being dispersed. the product is great and always has been. I'm 74 and it gives me the confidence that I am doing everything I can for the best-looking skin. I used to use .25 retinol every day. My skin since I've gotten older is so sensitive the retinol is a bit too strong for me. It used to itch on my neck area so bad I had to stop. It was a lot cheaper. I wish I could still do it. Niacidimide seems to also be a good new alternative in a not too strong version. Anyway, I adore my TNS Advanced Serum. I hope the price doesn't go up any time soon. I am stretching to afford it now. Love you guys!!!!!

3 people found this helpful

LovelySkin Customer

from Texas

Age Group: 70-79

Normal Skin

Verified Purchase

January 16, 2026

Skin Medica TNS

Great product. Visibly reduces sagging skin.

2 people found this helpful

Cindylee

from New York

Age Group: 60-69

Straight, Color treated hair

Normal Skin

Verified Purchase

January 14, 2026

Sensational

I’ve been using this for several years and people think I’m 20-15 years younger than I am .

2 people found this helpful

Matty617

from Massachusetts

Age Group: 60-69

Verified Purchase

January 13, 2026

Love

I don’t know is it makes a difference yet but i like using it. So far so good

0 people found this helpful

Bumperw

from Florida

Verified Purchase

January 06, 2026

Expectations not met

I read many reviews for this product, some by consumers and others by dermatologists, that were highly favorable. I expected this product to improve fine lines and firmness as well as to promote overall skin health. I just finished my third container and I see NO difference at all in my skin. I am canceling my autoship and will find a product that delivers. I mean really, a drug store product is probably as effective as this one. It was a dud for me.

3 people found this helpful

LovelySkin Customer

from Florida

Age Group: 50-59

Verified Purchase

January 06, 2026

Excellent

I have been using this off and on for several years and always go back. This gives my skin a softness and a radiance that no other product has provided. It has a very slight scent that I really like. I also think it has improved my under eye area. Overall, great results.

1 person found this helpful

Zydeco71

from Alabama

Age Group: 50-59

Straight, Dry Hair

Normal Skin

Verified Purchase

January 03, 2026

Holy grail… not sure

I have been using this for several years and like it because it has several products combined in one but I honestly do not think it is any better than drugstore products.

4 people found this helpful

LovelySkin Customer

from Nevada

Verified Purchase

January 02, 2026

What can I say

Did I want this to not work? Yes of course, for the price I was hoping it would be horrible and I could sigh in relief as I return it. However that was not the case, and I’m currently on my third restock. What can I say.. it’s worth it!

2 people found this helpful

LovelySkin Customer

from South Carolina

Verified Purchase

January 02, 2026

So far, so good

I’ve not used this long enough to see true benefit but I have used it long enough to see that it doesn’t clog my pores or irritate my combination, sensitive skin. Currently using on my face and neck.

1 person found this helpful

LouiseIP

Verified Purchase

December 31, 2025

Love it!

I look at myself in a mirror and see a woman 15 years younger only a few days after I started to use this cream

1 person found this helpful

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SkinMedica TNS® Advanced+ Serum - 3 Pack

Product Overview

SkinMedica TNS Advanced+ Serum - 3 Pack offers the classic formula, now supercharged.

Highlights

Ingredients

Directions

Shipping & Returns

Questions & Answers

Product Specifications

Special Offers

About the Brand

Customer Reviews (1925)

Overall Rating

Review Summary

Write a Review

Funky Smell & Bad Pump

Amazing

SkinMedica TNS Advanced Serum

Great Product at a Great Price

a must have serum

Still unsure

Dedicated TNS Advanced+ Serum user!

Great purchase!

One of My Favorites

TNS Advanced Miracle Prodent

TNS Advanced Serum

Skin Medica TNS

Sensational

Love

Expectations not met

Excellent

Holy grail… not sure

What can I say

So far, so good

Love it!

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