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SkinMedica TNS® Advanced+ Serum - 3 Pack

 
| HSA/FSA Eligible LMN Required
$796.50
$885.00 10% Off

Special Offer: 20% off use code DYSG26

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Highlights
  • Fragrance-free
  • Boosts collagen and elastin production
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Product Overview

SkinMedica TNS Advanced+ Serum - 3 Pack offers the classic formula, now supercharged.

This SkinMedica serum builds upon the legendary results of its predecessor for powerful anti-aging. Every piece of the TNS Essential serum, from the peptides to the growth factors has been rethought and amplified. Because of this, it's even better at softening wrinkles, diminishing dark spots and addressing other signs of aging.

Formulated with TNS-MR, the next-generation growth factor blend, this serum acts on multiple levels of the skin to achieve the best results. Additionally, Renessensce (RSC) Advanced, a highly active blend of botanicals, peptides and marine extracts, supports skin renewal for plumper, more youthful skin, delivering results in as little as two weeks.

Set Includes:

  • SkinMedica TNS Advanced+ Serum (3 x 1.0 fl oz)

Key Features:

  • New Innovative 2 Tripeptide Complex visibly firms and smooths fine lines and wrinkles
  • Potent blend of Spanish Marine extract and Green Microalgae builds collagen and supports skin's repair process
  • Provides antioxidants for improved defense against environmental stress
  • Visibily lifts sagging skin while improving skin tone and texture
  • In studies, users felt they looked up to 6 years younger after 12 weeks
  • Fragrance-free and paraben-free

Experience a breakthrough in anti-aging science with SkinMedica TNS Advanced+ Serum.

Highlights

  • Fragrance-free
  • Boosts collagen and elastin production
  • Contains growth factors

Ingredients

Directions

Shipping & Returns

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ORM-D classified products such as aerosol sprays, nail polish, perfume and products with high alcohol content may only be shipped using a ground method within the Continental US.

Availability: In stock & ready to ship! .

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Product Specifications

About the Brand

Customer Reviews (2061)

Overall Rating

4.6
Based on 2061 reviews

Review Summary

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2061 Reviews

Profile picture of ChristineM.

ChristineM

from Pennsylvania

Age Group: 50-59

Wavy, Dry Hair

Mature Skin

Verified Purchase

October 31, 2026

Pricey but Worth Every Penny—A Staple for Years!

I have been using SkinMedica TNS Advanced+ Serum for years, and it is a permanent staple in my skincare routine. It does an incredible job of keeping my skin deeply hydrated and noticeably firm. While the high price tag definitely hurts my wallet, the visible results make it absolutely worth every penny.

0 people found this helpful

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LovelySkin Customer

Age Group: 60-69

Wavy, Dry Hair

Dry Skin

Verified Purchase

October 26, 2026

Too soon to tell

Although the consistency is nice, the packaging makes it impossible to know when the bottle will be empty. Unless I see amazing results, not sure I will repurchase

1 person found this helpful

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LovelySkin Customer

from Virginia

Age Group: 60-69

Normal Skin

Verified Purchase

October 24, 2026

The Holy Grail of Skin Care

I've been using this for years and It is my #1 anti aging skin care product. It keeps my skin glowing and looking firm, even in my 60's. Highly recommend for every skin care routine.

1 person found this helpful

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LovelySkin Customer

from North Carolina

Age Group: 60-69

Verified Purchase

October 24, 2026

New Pump Runs Out Quicker

I have been using TNS for atleast 10 years with great results. Only the last two with the older pump were faulty. What changed? Now that I have used two with the new pump, one side runs out much quicker and only lasts 1/2 as long as the original pump did. This product is already too expensive and reluctantly I have been researching alternative products. Please find a better pump so I don’t have to switch!

10 people found this helpful

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NobleRose

from New Hampshire

Age Group: 70-79

Mature Skin

Verified Purchase

October 24, 2026

Pricey but well worth it!

I’ve been using this for years & love the results. It glides over my face & instantly preps my face for moisturizer.

0 people found this helpful

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LovelySkin Customer

from Florida

Age Group: 60-69

Combination Skin

Verified Purchase

October 21, 2026

Skin Medica TNS Advanced + Serum

I have used TNS Advanced +Serum for five years. It has made a big difference in my facial routine each day. It has reduce wrinkles, sun spots and the texture of my face. It has also helped replenish cologen in my skin as well. This is a product that I will continue to use.

1 person found this helpful

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LovelySkin Customer

from California

Age Group: 80+

Mature Skin

Verified Purchase

October 20, 2026

Loving TNS Advanced for years

I am 83 years young and I have been told often that I look at least 10 to 15 years younger than my age. I attribute this to good genes and Skin Medica TNS advanced. I really and truly love the new packaging. Thank for listening to your customers.

1 person found this helpful

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LovelySkin Customer

from Missouri

Age Group: 40-49

Wavy Hair

Verified Purchase

October 15, 2026

Definitely smoother skin

I have only been using this for a little over two weeks and I can definitely tell a difference in the appearance of my skin. My skin looks and feels smoother and brighter. I can't wait to see the difference after using it long term.

2 people found this helpful

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LovelySkin Customer

from Tennessee

Age Group: 50-59

Wavy Hair

Normal Skin

Verified Purchase

October 14, 2026

A Skincare Staple Worth the Investment!

SkinMedica TNS Advanced+ Serum has become one of my favorite skincare products. I love how it makes my skin feel smoother, firmer, and more hydrated. It’s lightweight, absorbs beautifully, and layers well with my other skincare products. I appreciate a product that focuses on improving skin quality rather than just providing a temporary glow. Although it’s pricey, I feel it’s a worthwhile investment in maintaining healthy, youthful-looking skin. Definitely a staple in my skincare routine

3 people found this helpful

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LovelySkin Customer

from Minnesota

Age Group: 70-79

Verified Purchase

October 12, 2026

Luxury in feel and easy to use day and night

I just started using this and already feel like it is a winner!

1 person found this helpful

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Daphne1

from California

Age Group: 70-79

Dry Skin

Verified Purchase

October 09, 2026

5 stars in waiting?

I haven’t used this too long but am liking A LOT what I am seeing. It seems to have softened lines and skin clearer. It is frightfully expensive so it will need to definitely become 5 star worthy if I purchase again but so far so good!

3 people found this helpful

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LovelySkin Customer

from Tennessee

Age Group: 60-69

Verified Purchase

October 08, 2026

The Gold Standard in Skin Care

I never want to run out of this product!!!!

1 person found this helpful

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LovelySkin Customer

Verified Purchase

October 07, 2026

Good product

I like this product a lot, but I'm not sure how much difference it makes for the price. I only purchase it when it's on sale, and I want to try one more round, but the cost for the amount is a lot. It didn't seem to last very long, and I only used it once a day.

5 people found this helpful

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LovelySkin Customer

from Florida

Age Group: 30-39

Wavy Hair

Oily Skin

Verified Purchase

September 30, 2026

Amazing product!

I’ve been using for 2 years already & it’s one of my favorite products for anti-aging! Big fan of skin medica…highly recommended!

2 people found this helpful

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btdt2

from Missouri

Age Group: 60-69

Verified Purchase

September 26, 2026

A Fan For Life!

What I love most about SkinMedica’s TNS Advanced+ Serum on a daily basis is how immediately satisfying it is to use. The texture is lightweight, absorbs effortlessly, and layers beautifully under my other products. From the very first week, it has kept my skin feeling incredibly soft, touchably smooth, and deeply hydrated. It gives my complexion that coveted plump, healthy, dewy look that makes me feel like I just stepped out of a high-end medical spa. For anyone hesitant about the investment, take it from someone who uses it religiously: it works. It doesn't just rest on top of your skin; it completely transforms your texture from the inside out. If you want a product that backs up its claims with actual visible smoothness and firmness, this is it. SkinMedica has a fan for life!

4 people found this helpful

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LovelySkin Customer

from Illinois

Age Group: 50-59

Wavy, Dry Hair

Mature Skin

Verified Purchase

September 26, 2026

Soft, glowing skin

Love this serum! TNS Advanced+ has quickly become one of my favorite skincare products. My skin feels smoother, firmer, and more hydrated, and I’ve noticed an overall improvement in its texture and appearance. It’s definitely an investment, but a little goes a long way and I feel like I’m actually seeing results. Worth the splurge!

4 people found this helpful

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Megg

from Texas

Age Group: 50-59

Wavy, Dry Hair

Dry Skin

Verified Purchase

September 23, 2026

Seems to be working well

This seems to be helping the texture of my skin. I'm noticing less fine lines and crepiness. Only negative is that one side of the formula often seems to run out more quickly than the other even though I use equal amounts each time.

8 people found this helpful

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LovelySkin Customer

from Oregon

Age Group: 50-59

Wavy, Color treated hair

Mature Skin

Verified Purchase

September 23, 2026

The Best

I've been using TNS 2x daily, including on my neck, for about 8 weeks. The softening of fine lines (and even deeper ones) is noticeable. I also use Skinmedica's Instant Bright Eye Cream. I finally ordered the Neck Correct Cream and will start using that for more focused treatment there, but TNS is a permanent part of my skincare routine.

6 people found this helpful

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LovelySkin Customer

from Nebraska

Verified Purchase

September 22, 2026

Favorite skin care

Makes your skin feel great

4 people found this helpful

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LovelySkin Customer

from Illinois

Verified Purchase

September 22, 2026

Love!

I would bathe in this serum if I could. I have used it for over 12 years and love how my face feels and looks.

5 people found this helpful

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