The beloved SkinMedica TNS Advanced+ Serum is a gold standard in anti-aging skin care. This award-winning formula delivers smoother, firmer, more radiant-looking skin and remains a favorite among skin care enthusiasts. Now, prepare to fall in love again as SkinMedica has introduced updated, thoughtful packaging featuring an improved dual-pump system designed for consistent, reliable delivery with every use.

Whether you’re already devoted to this bestseller or interested in adding a high-performance treatment to your regimen, the newly refreshed SkinMedica TNS Advanced+ Serum blends the same clinically proven results with a more intuitive, elegant design. Below, we’re breaking down what’s new, what’s inside and why this formula continues to be one of the most trusted in advanced skin care.

Bestselling formula, new elevated design

For years, SkinMedica TNS Advanced+ Serum has been a go-to for those looking to dramatically diminish the appearance of fine lines, wrinkles, sagging skin and uneven skin tone. Its dual-chamber technology separates two advanced formulas until the moment of application, ensuring maximum potency.

The newly refreshed packaging keeps this same science-first approach while incorporating an improved delivery experience encased in an elegant, modern-looking bottle. The brand’s upgraded dual-pump system ensures both chambers dispense the right amount of product—no guesswork or uneven blending. Long-time fans will appreciate how much easier and more consistent this new design is to use.

It’s the same clinical power you rely on, now with packaging that works even harder.

What’s improved about the dual-pump system

The most notable update is the new dual-pump design. The redesigned actuator offers:

• More consistent dispensing for both chambers
• Even blending of the two formulas
• Improved reliability (especially for users who struggled with older packaging)
• A smoother, more intuitive application experience

For anyone who has ever had concerns with their skinmedica tns pump not working, this updated packaging is a welcome improvement.

The formulas inside each dual chamber

While the look has changed, what’s inside remains the same highly respected, science-backed formula that sets SkinMedica TNS Advanced+ Serum apart.

Chamber 1: TNS-MR

This chamber features TNS-MR, SkinMedica’s most advanced growth factor technology to date. This next-gen blend includes powerful peptides and growth factors that work together to support the skin’s natural rejuvenation processes. The result? Skin that looks smoother, firmer and more youthful over time.

Chamber 2: RENESSENSCE (RSC) Advanced

The second chamber contains RENESSENSCE (RSC) Advanced, a potent combination of botanicals, marine extracts and peptides. This formula supports skin renewal, defends against environmental stressors and helps improve skin tone and texture.

Together, the two chambers deliver comprehensive skin rejuvenation, lifting, smoothing and brightening with consistent, long-term results.

How to use SkinMedica TNS Advanced+ Serum

Not sure how to use this iconic formula? SkinMedica keeps it simple, and the new packaging helps ensure the very best results.

• Step 1: Dispense one pump from each chamber onto the palm of your hand.
• Step 2: Blend the two formulas together.
• Step 3: Apply to clean, dry skin in the morning and evening.
• Step 4: Follow with moisturizer and sunscreen during the day.

Because this is a highly active formula, consistency is key. Most users begin to see visible improvements in skin texture and firmness within just a few weeks, with more significant results over time.

Why we love it

While the packaging is new, the results that have made this skin care favorite a top choice remain unchanged. In addition to boosting overall radiance, this advanced formula helps to improve the appearance of fine lines and wrinkles, firm sagging skin and improve uneven skin texture.

The multi-action formula is trusted by dermatologists and patients alike, delivering clinically proven results without requiring a complicated routine. Now, the newly designed dual pump system ensures precise delivery for optimal results you can see.

The bottom line

The refreshed packaging and upgraded dual-pump system highlight SkinMedica’s commitment to innovation. The beloved formula beloved remains while the new design simply makes it easier, more intuitive and more enjoyable to use.

If you’ve been considering trying SkinMedica TNS Advanced+ Serum, or you’re revamping your skin care routine, it’s the perfect time to experience these transformative results for yourself.

Looking to update your skin care routine with more SkinMedica favorites? See SkinMedica’s top five firming products for GLP-1 users.