View more from Osmosis

Osmosis Rescue Epidermal Repair Serum

(formerly known as Osmosis Skincare MD Rescue Epidermal Repair Serum)
 
| HSA|FSA Eligible LMN Required
$102.00
$136.00 25% Off
Highlights
  • Reduces the appearance of redness
  • Works on all skin types
  • Repairs damage from free radicals
Availability depends on selected option

Buy Now, Pay Later or
Free, fast shipping all U.S. orders, no minimums. 2-3 day delivery, most orders
Learn More
Authorized Retailer of Osmosis
Authorized Retailer
Never receive a fake product
Learn More

Product Overview

Osmosis Rescue Epidermal Repair Serum helps calm, refine and repair skin.

This serum calms and heals skin with a patented anti-inflammatory ingredient called Trioxolane. Also known as ozonized ethyl oleate, it's a specialized extract of sweet wormwood that has a remarkable ability to detoxify, calm inflammation, activate healing and dramatically improve skin texture. The powerful formula works for all skin types, and especially helps those with acne or rosacea. 

Key Features: 

  • Helps to clear blemishes
  • Enhances tone and radiance
  • Reduces skin irritation

Highlights

  • Reduces the appearance of redness
  • Works on all skin types
  • Repairs damage from free radicals

Ingredients

Directions

Shipping & Returns

Free U.S. Shipping. Period. View Our Shipping Policy

Return Policy: This product is non-returnable

Return Policy: View Our Return Policy

Special Shipping Requirements: ORM-D Class
ORM-D classified products such as aerosol sprays, nail polish, perfume and products with high alcohol content may only be shipped using a ground method within the Continental US.

Availability: Depends on selected option.

Questions & Answers

Submit your question about this product to our talented team of Customer Care Representatives, and we'll get back to you as soon as possible!


Product Specifications

About the Brand

Customer Reviews (117)

Overall Rating

4.6
Based on 117 reviews

Review Summary

Write a Review

You can receive 50 rewards points by sharing your honest opinion of Osmosis Rescue Epidermal Repair Serum.

Read all reviews

117 Reviews

Profile picture of Hn25.

Hn25

Verified Purchase

September 02, 2025

Effective and good for sensitive skin with acne

I did not have high hopes for this, considering the smell is not the best. But for my skin, which is dry, sensitive, and rosacea-type prone, it really is nice, calming, and very effective on acne! Definitely a helpful treatment!

0 people found this helpful

Profile picture of KellyPerk.

KellyPerk

Verified Purchase

July 29, 2025

Totally Amazing!

I tried this on a whim and boy am I glad I did. It’s like magic in a bottle. I’m 39 and still get breakouts frequently .. this stuff manages to calm them and add moisture enough to not feel ‘tacky’ and gross! Will buy again!

0 people found this helpful

Profile picture of Jog1.

Jog1

Verified Purchase

July 06, 2025

My skin is brighter

This serum cleared up my ugly rosacea and my skin lost all the redness. It looks so bright and makes me feel so much more confident. I’m 73 and looking pretty good without makeup now.

0 people found this helpful

Default profile picture.

LovelySkin Customer

Verified Purchase

March 09, 2025

It works!

My daughter uses this to keep her skin calm and when she stops using it her skin will flare up.

1 person found this helpful

Default profile picture.

LovelySkin Customer

Verified Purchase

November 17, 2024

Love it

The smell is something to get used to, but I love this stuff!

0 people found this helpful

Default profile picture.

LovelySkin Customer

Verified Purchase

September 28, 2024

Excellent serum

This serum is pure magic. I have struggled with acne, very dry skin and more recently rosacea. My skin barrier was a mess. Recommended this rescue serum by a skin specialist and after a short while my skin was immensely improved. I have now been using it for two years and my skin is the best it has ever been. Wouldn’t be without it.

1 person found this helpful

Default profile picture.

LovelySkin Customer

Verified Purchase

August 02, 2024

Great product but bad bottle

I love this product and have seen amazing results. However they changed the bottle of the product and it sucks. I wish they would go back to the old bottle type.

1 person found this helpful

Profile picture of Jaspie.

Jaspie

Verified Purchase

July 02, 2024

Calming

Always love this product helps to calm inflammation and speed healing in breakouts. Smells funny but worth it!

0 people found this helpful

Profile picture of Miller.

Miller

Verified Purchase

July 01, 2024

Highly recommend for sensitive skin

I absolutely love this serum. I have sensitive skin and so many products flare my rosacea and/or cause breakouts. This repair serum absorbs immediately. It helps calm my skin and I notice significantly less redness and irritation. It works well with other products and does not ball up under makeup.

0 people found this helpful

Profile picture of LSCustomer.

LSCustomer

Verified Purchase

June 28, 2024

Osmosis Rescue Epidermal Repair Serum

I like it.

0 people found this helpful

Profile picture of JackieSH.

JackieSH

Verified Purchase

June 03, 2024

Perfect Serum for Combination Skin with Rosacea

I am thrilled with this serum! It does a fantastic job of soothing my combination skin with rosacea. The product absorbs instantly, leaving no sticky or greasy residue. After application, my skin feels hydrated and matte, which is a significant plus for me. I highly recommend this serum to anyone with sensitive skin and redness issues!

0 people found this helpful

Default profile picture.

LovelySkin Customer

Verified Purchase

May 06, 2024

Helps control redness!

Great for controlling redness. Smooth overall serum.

0 people found this helpful

Profile picture of MarisaZ.

MarisaZ

Verified Purchase

April 22, 2024

Holy grail

I was introduced to Rescue by my esthetician 3 years ago and have not stopped using this since. I have dry skin and suffer from hormonal breakouts this keeps my skin in check. I notice less breakouts and redness. I wish they made a bigger bottle!

1 person found this helpful

Profile picture of Sam08.

Sam08

Verified Purchase

February 20, 2024

Amazingly soothing!

This serum is amazingly soothing. It reduces inflammation and heals like magic.

0 people found this helpful

Profile picture of brittanymackey.

brittanymackey

Verified Purchase

February 02, 2024

Rescue Serum

Worth the money - evens out skin tone and shrinks pores

1 person found this helpful

Default profile picture.

LovelySkin Customer

Verified Purchase

January 11, 2024

Lifesaver for Sensitive Acne-Prone Skin

I have tried proabably thousands of products, prescription and over the counter, in the past 15 years. Nothing has done a better job at managing my acne and calming my skin than the Osmosis Epidermal Repair serum. I was desperate after receiving an unhelpful laser treatment from a well-known dermatologist and various forms of prescription tretinoin. Nothing ever stopped my acne. I saw an esthetician, and she suggested this product because my skin was so irritated and sensitive and had developed signs of rosacea. My inflamed acne nearly disappeared. I still get small clogged pores every once in a while, but the deep, red acne that had caused me so much discomfort and embarassment is now an extremely rare occurrence. I know this isn't a cheap product - and I'm not rich - but I will always repurchase knowing what it does for my skin. It is 100% worth it and I would recommend to anyone dealing with the frustration of persisitent acne and sensitivity.

2 people found this helpful

Profile picture of kzmhealth.

kzmhealth

Verified Purchase

December 22, 2023

Gentle but effective

I’ve been using Rescue serum For two Years now every morning. It’s gentle on my skin and calms the redness and occasional breakout. Only reason it’s not getting 5 stars is the price!

0 people found this helpful

Profile picture of Jsfritz.

Jsfritz

Verified Purchase

December 01, 2023

Clear Skin

This product is fantastic! I have roseca and have tried a lot of products, prescription and non- prescription, and I highly recommend this product.. My face is finally clear.

0 people found this helpful

Profile picture of LPJ.

LPJ

Verified Purchase

November 28, 2023

Great Product!

Rescue is a wonderful product for blemishes. One or two applications and your blemishes are gone!

0 people found this helpful

Default profile picture.

LovelySkin Customer

Verified Purchase

July 05, 2023

No more blemishes!

I was skeptical that I would have to give up the other treatments I use to control my out of control hormonal acne. The week I started using this my skin became calm and clear. I have almost finished the first bottle and have not had a single serious acne outbreak since starting this amazing serum. I have stopped taking the daily antibiotics I was prescribed and all the other prescription creams and lotions. The only problem I have with this product is the price but it is worth every penny to not have to use all the prescriptions that don't even work. I use this serum twice a day after cleansing. It is amazing.

0 people found this helpful

Top Picks



Loading
Return to the top